[{"orgOrder":0,"company":"ZYMEDI","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Cardiology\/Vascular Diseases","country":"SOUTH KOREA","productType":"Other Large Molecule","year":"2024","type":"Inapplicable","leadProduct":"ZMA001","moa":"Undisclosed","graph1":"Cardiology\/Vascular Diseases","graph2":"Phase I","graph3":"ZYMEDI","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Cardiovascular Diseases","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"ZYMEDI \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"ZYMEDI \/ Inapplicable"},{"orgOrder":0,"company":"ZYMEDI","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Cardiology\/Vascular Diseases","country":"SOUTH KOREA","productType":"Other Large Molecule","year":"2024","type":"Inapplicable","leadProduct":"ZMA001","moa":"Undisclosed","graph1":"Cardiology\/Vascular Diseases","graph2":"Phase I","graph3":"ZYMEDI","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Cardiovascular Diseases","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"ZYMEDI \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"ZYMEDI \/ Inapplicable"},{"orgOrder":0,"company":"ZYMEDI","sponsor":"National Heart, Lung, And Blood Institute","pharmaFlowCategory":"D","therapeuticArea":"Cardiology\/Vascular Diseases","country":"SOUTH KOREA","productType":"Other Large Molecule","year":"2023","type":"Collaboration","leadProduct":"ZMA001","moa":"Undisclosed","graph1":"Cardiology\/Vascular Diseases","graph2":"Phase I","graph3":"ZYMEDI","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Cardiovascular Diseases","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"ZYMEDI \/ National Heart, Lung, And Blood Institute","highestDevelopmentStatusID":"6","companyTruncated":"ZYMEDI \/ National Heart, Lung, And Blood Institute"}]

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                          Top Deals by Deal Size (USD bn)

                          01

                          EASL Congress
                          Not Confirmed
                          EASL Congress
                          Not Confirmed

                          Details : ZMA001 (BC-NKA-20008) is a first-in-class therapeutic antibody targeting KARS1 that is specific to monocytes & macrophages. It is being evaluated for the treatment of pulmonary arterial hypertension.

                          Product Name : ZMA001

                          Product Type : Other Large Molecule

                          Upfront Cash : Inapplicable

                          July 30, 2024

                          Lead Product(s) : ZMA001

                          Therapeutic Area : Cardiology/Vascular Diseases

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          EASL Congress
                          Not Confirmed
                          EASL Congress
                          Not Confirmed

                          Details : ZMA001 is a first-in-class therapeutic antibody targeting KARS1, specific to monocytes and macrophages, under phase 1 trials for treating pulmonary arterial hypertension.

                          Product Name : ZMA001

                          Product Type : Other Large Molecule

                          Upfront Cash : Inapplicable

                          July 02, 2024

                          Lead Product(s) : ZMA001

                          Therapeutic Area : Cardiology/Vascular Diseases

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          EASL Congress
                          Not Confirmed
                          EASL Congress
                          Not Confirmed

                          Details : The agreement aims to develop ZMA001, a novel monoclonal antibody targeting pathways thought to play a key role in PAH pathogenesis, for the treatment of pulmonary arterial hypertension (PAH).

                          Product Name : ZMA001

                          Product Type : Other Large Molecule

                          Upfront Cash : Undisclosed

                          February 07, 2023

                          Lead Product(s) : ZMA001

                          Therapeutic Area : Cardiology/Vascular Diseases

                          Highest Development Status : Preclinical

                          Sponsor : National Heart, Lung, And Blood Institute

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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