Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Sovilnesib
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Volastra Therapeutics Doses First Patient in Phase Ib Trial of Sovilnesib
Details : AMG-650 (sovilnesib) is a KIF18A inhibitor, small molecule drug, which is being evaluated for the treatment of patients with platinum-resistant or refractory high-grade serous ovarian cancer.
Product Name : AMG 650
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
April 16, 2024
Lead Product(s) : Sovilnesib
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : VLS-1488
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Volastra Receives FDA Fast Track Designation for KIF18A Inhibitor in Ovarian Cancer
Details : VLS-1488 is a potent, oral and clinical-stage KIF18A inhibitor with the potential to be the first-ever chromosomal instability-targeted cancer therapy.
Product Name : VLS-1488
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
February 10, 2024
Lead Product(s) : VLS-1488
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : VLS-1488
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : VLS-1488 is a potent, oral and clinical-stage KIF18A inhibitor with the potential to be the first-ever chromosomal instability-targeted cancer therapy.
Product Name : VLS-1488
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
October 30, 2023
Lead Product(s) : VLS-1488
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Sovilnesib
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Polaris Partners
Deal Size : $60.0 million
Deal Type : Series A Financing
Details : The Funding will support clinical development of Volastra’s portfolio of KIF18A inhibitors including, AMG650 (sovilnesib), an oral, first-in-class small molecule, as well as advancement of a robust pipeline of research programs targeting chromosomally ...
Product Name : AMG 650
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
July 03, 2023
Lead Product(s) : Sovilnesib
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Polaris Partners
Deal Size : $60.0 million
Deal Type : Series A Financing
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Treatment with KIF18A inhibitor led to substantial, dose-dependent inhibition of tumor growth in multiple tumor models, with no effect on normal cells.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Inapplicable
September 09, 2022
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Volastra Therapeutics Announces Drug Discovery Collaboration with Bristol Myers Squibb
Details : Under the terms of agreement, Volastra will be responsible for conducting activities for undisclosed targets. For select targets, Volastra will conduct all research activities through development candidate and BMS may take the responsibilities for all su...
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : $30.0 million
March 21, 2022