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Find Clinical Drug Pipeline Developments & Deals by Volastra Therapeutics

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          PEGS Boston Summit
                          Not Confirmed
                          PEGS Boston Summit
                          Not Confirmed

                          Details : AMG-650 (sovilnesib) is a KIF18A inhibitor, small molecule drug, which is being evaluated for the treatment of patients with platinum-resistant or refractory high-grade serous ovarian cancer.

                          Product Name : AMG 650

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          April 16, 2024

                          Lead Product(s) : Sovilnesib

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          PEGS Boston Summit
                          Not Confirmed
                          PEGS Boston Summit
                          Not Confirmed

                          Details : VLS-1488 is a potent, oral and clinical-stage KIF18A inhibitor with the potential to be the first-ever chromosomal instability-targeted cancer therapy.

                          Product Name : VLS-1488

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          February 10, 2024

                          Lead Product(s) : VLS-1488

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          PEGS Boston Summit
                          Not Confirmed
                          PEGS Boston Summit
                          Not Confirmed

                          Details : VLS-1488 is a potent, oral and clinical-stage KIF18A inhibitor with the potential to be the first-ever chromosomal instability-targeted cancer therapy.

                          Product Name : VLS-1488

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          October 30, 2023

                          Lead Product(s) : VLS-1488

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          PEGS Boston Summit
                          Not Confirmed
                          PEGS Boston Summit
                          Not Confirmed

                          Details : The Funding will support clinical development of Volastra’s portfolio of KIF18A inhibitors including, AMG650 (sovilnesib), an oral, first-in-class small molecule, as well as advancement of a robust pipeline of research programs targeting chromosomally ...

                          Product Name : AMG 650

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          July 03, 2023

                          Lead Product(s) : Sovilnesib

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Polaris Partners

                          Deal Size : $60.0 million

                          Deal Type : Series A Financing

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                          05

                          PEGS Boston Summit
                          Not Confirmed
                          PEGS Boston Summit
                          Not Confirmed

                          Details : Treatment with KIF18A inhibitor led to substantial, dose-dependent inhibition of tumor growth in multiple tumor models, with no effect on normal cells.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Inapplicable

                          September 09, 2022

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          PEGS Boston Summit
                          Not Confirmed
                          PEGS Boston Summit
                          Not Confirmed

                          Details : Under the terms of agreement, Volastra will be responsible for conducting activities for undisclosed targets. For select targets, Volastra will conduct all research activities through development candidate and BMS may take the responsibilities for all su...

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : $30.0 million

                          March 21, 2022

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Oncology

                          Highest Development Status : Discovery

                          Sponsor : Bristol Myers Squibb

                          Deal Size : $1,130.0 million

                          Deal Type : Collaboration

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