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Find Clinical Drug Pipeline Developments & Deals by Vaxxinity
Details :
The collaboration aims to helps Vaxxinity to work on the development of UB-311, which targets toxic forms of aggregated Aβ in the brain to fight Alzheimer disaease.
Details :
The collaboration furthers Vaxxinity’s development of active immunotherapies for muscle and bone wasting, assessing effects on undisclosed proteins in vitro, in vivo, and animal models.
Details :
UB-312 is a vaccine candidate targeting pathological forms of alpha-synuclein (aSyn) for the disease-modifying treatment and prevention of Parkinson’s disease (PD) and other synucleinopathies.
Details :
VXX-401 is an investigational vaccine designed to lower low-density lipoprotein (LDL) cholesterol, a known factor contributing to heart disease, by targeting proprotein convertase subtilisin/kexin type 9 serine protease (PCSK9).
Details :
UB-612 is the first multitope subunit protein/peptide-based vaccine candidate for SARS-CoV-2, which is designed to activate both B- and T-cell arms of the immune system directed against multiple structural viral antigens.
Details :
The first patient has been dosed for UB-312 Part B of Phase 1 Clinical trial on the basis of results from Part A of Clinical trial which demonstrated that UB-312 was generally safe and well-tolerated at multiple dose levels.
Details :
The funds will be used to investigate whether Protein Misfolding Cyclic Amplification (PMCA) could be implemented as a robust method to assess target engagement in subjects immunized with UB-312.
Details :
Preclinically, UB-313 has shown strong immunogenicity across species, inducing anti-CGRP antibodies with similar properties as approved comparator monoclonal antibodies, as well as a favorable safety and tolerability profile.
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