[{"orgOrder":0,"company":"Frontage Laboratories, Inc","sponsor":"Silo Pharma","pharmaFlowCategory":"D","therapeuticArea":"Psychiatry\/Psychology","country":"U.S.A","productType":"Miscellaneous","year":"2025","type":"Agreement","leadProduct":"SPC-15","moa":"Undisclosed","graph1":"Psychiatry\/Psychology","graph2":"IND Enabling","graph3":"Frontage Laboratories, Inc","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Psychiatry","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Frontage Laboratories, Inc \/ Frontage Laboratories, Inc","highestDevelopmentStatusID":"5","companyTruncated":"Frontage Laboratories, Inc \/ Frontage Laboratories, Inc"},{"orgOrder":0,"company":"Frontage Laboratories, Inc","sponsor":"Eisai","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"U.S.A","productType":"Antibody, Unconjugated","year":"2022","type":"Partnership","leadProduct":"Lecanemab","moa":"Amyloid-beta A4 protein","graph1":"Neurology","graph2":"Phase III","graph3":"Frontage Laboratories, Inc","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Frontage Laboratories, Inc \/ Eisai","highestDevelopmentStatusID":"10","companyTruncated":"Frontage Laboratories, Inc \/ Eisai"},{"orgOrder":0,"company":"Tigermed","sponsor":"Tigermed","pharmaFlowCategory":"DU","therapeuticArea":"Gastroenterology","country":"ITALY","productType":"Miscellaneous","year":"2023","type":"Inapplicable","leadProduct":"Diosmin","moa":"Aryl hydrocarbon receptor","graph1":"Gastroenterology","graph2":"Undisclosed","graph3":"Tigermed","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Gastroenterology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Tigermed \/ Tigermed","highestDevelopmentStatusID":"1","companyTruncated":"Tigermed \/ Tigermed"},{"orgOrder":0,"company":"Frontage Laboratories, Inc","sponsor":"Mira Pharmaceuticals","pharmaFlowCategory":"DU","therapeuticArea":"Psychiatry\/Psychology","country":"U.S.A","productType":"Controlled Substance","year":"2024","type":"Inapplicable","leadProduct":"Ketamine Hydrochloride","moa":"Glutamate [NMDA] receptor","graph1":"Psychiatry\/Psychology","graph2":"Preclinical","graph3":"Frontage Laboratories, Inc","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Psychiatry","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Frontage Laboratories, Inc \/ Frontage Laboratories, Inc","highestDevelopmentStatusID":"4","companyTruncated":"Frontage Laboratories, Inc \/ Frontage Laboratories, Inc"},{"orgOrder":0,"company":"Tigermed","sponsor":"Shanghai Zhimeng Biopharma","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"CHINA","productType":"Miscellaneous","year":"2022","type":"Inapplicable","leadProduct":"ZM-H1505R","moa":"Hepatitis B virus Capsid protein (HBV C)","graph1":"Infections and Infectious Diseases","graph2":"Phase III","graph3":"Tigermed","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Tigermed \/ Tigermed","highestDevelopmentStatusID":"10","companyTruncated":"Tigermed \/ Tigermed"},{"orgOrder":0,"company":"Tigermed","sponsor":"Swedish Orphan Biovitrum AB","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"SWEDEN","productType":"Protein","year":"2024","type":"Inapplicable","leadProduct":"Anakinra","moa":"Interleukin-1 receptor","graph1":"Genetic Disease","graph2":"Phase IV","graph3":"Tigermed","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Injection","sponsorNew":"Tigermed \/ Tigermed","highestDevelopmentStatusID":"11","companyTruncated":"Tigermed \/ Tigermed"},{"orgOrder":0,"company":"Tigermed","sponsor":"CSL Vifor","pharmaFlowCategory":"DU","therapeuticArea":"Dermatology","country":"SWITZERLAND","productType":"Protein","year":"2023","type":"Inapplicable","leadProduct":"Difelikefalin Acetate","moa":"Kappa opioid receptor","graph1":"Dermatology","graph2":"Phase III","graph3":"Tigermed","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Dermatology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Tigermed \/ Tigermed","highestDevelopmentStatusID":"10","companyTruncated":"Tigermed \/ Tigermed"},{"orgOrder":0,"company":"Tigermed","sponsor":"CSL Vifor","pharmaFlowCategory":"DU","therapeuticArea":"Nephrology","country":"SWITZERLAND","productType":"Protein","year":"2023","type":"Inapplicable","leadProduct":"Difelikefalin Acetate","moa":"Kappa opioid receptor","graph1":"Nephrology","graph2":"Phase I","graph3":"Tigermed","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Nephrology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Tigermed \/ Tigermed","highestDevelopmentStatusID":"6","companyTruncated":"Tigermed \/ Tigermed"},{"orgOrder":0,"company":"Tigermed","sponsor":"CSL Vifor","pharmaFlowCategory":"DU","therapeuticArea":"Nephrology","country":"SWITZERLAND","productType":"Dietary Supplement","year":"2021","type":"Inapplicable","leadProduct":"Patiromer","moa":"Potassium","graph1":"Nephrology","graph2":"Phase III","graph3":"Tigermed","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Nephrology","amount2New":0,"dosageForm":"Suspension","sponsorNew":"Tigermed \/ Tigermed","highestDevelopmentStatusID":"10","companyTruncated":"Tigermed \/ Tigermed"},{"orgOrder":0,"company":"Tigermed","sponsor":"Zhejiang Hisun Pharmaceutical","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"CHINA","productType":"Miscellaneous","year":"2020","type":"Inapplicable","leadProduct":"Favipiravir","moa":"RNA-directed RNA polymerase","graph1":"Infections and Infectious Diseases","graph2":"Phase III","graph3":"Tigermed","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Tigermed \/ Tigermed","highestDevelopmentStatusID":"10","companyTruncated":"Tigermed \/ Tigermed"},{"orgOrder":0,"company":"Tigermed","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"CHINA","productType":"Vaccine","year":"2021","type":"Inapplicable","leadProduct":"Ad5-nCoV","moa":"SARS-CoV-2 S","graph1":"Infections and Infectious Diseases","graph2":"Phase III","graph3":"Tigermed","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Injection","sponsorNew":"Tigermed \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Tigermed \/ Undisclosed"},{"orgOrder":0,"company":"Tigermed","sponsor":"Zhuhai Trinomab Pharmaceutical","pharmaFlowCategory":"DU","therapeuticArea":"Undisclosed","country":"CHINA","productType":"Undisclosed","year":"2020","type":"Inapplicable","leadProduct":"TNM002","moa":"Undisclosed","graph1":"Undisclosed","graph2":"Phase I","graph3":"Tigermed","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"","amount2New":0,"dosageForm":"Injection","sponsorNew":"Tigermed \/ Tigermed","highestDevelopmentStatusID":"6","companyTruncated":"Tigermed \/ Tigermed"},{"orgOrder":0,"company":"Tigermed","sponsor":"Multitude Therapeutics","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Undisclosed","year":"2022","type":"Inapplicable","leadProduct":"AMT-151","moa":"Undisclosed","graph1":"Oncology","graph2":"Phase I","graph3":"Tigermed","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Tigermed \/ Tigermed","highestDevelopmentStatusID":"6","companyTruncated":"Tigermed \/ Tigermed"},{"orgOrder":0,"company":"Tigermed","sponsor":"HighField Biopharmaceuticals","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"CHINA","productType":"Miscellaneous","year":"2022","type":"Inapplicable","leadProduct":"HF1K16","moa":"Undisclosed","graph1":"Oncology","graph2":"Phase I","graph3":"Tigermed","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Suspension","sponsorNew":"Tigermed \/ Tigermed","highestDevelopmentStatusID":"6","companyTruncated":"Tigermed \/ Tigermed"},{"orgOrder":0,"company":"Tigermed","sponsor":"Immorna","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Vaccine","year":"2024","type":"Inapplicable","leadProduct":"JCXH-105","moa":"Undisclosed","graph1":"Infections and Infectious Diseases","graph2":"Phase II","graph3":"Tigermed","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Injection","sponsorNew":"Tigermed \/ Tigermed","highestDevelopmentStatusID":"8","companyTruncated":"Tigermed \/ Tigermed"},{"orgOrder":0,"company":"Tigermed","sponsor":"Immorna","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Vaccine","year":"2024","type":"Inapplicable","leadProduct":"JCXH-108","moa":"Undisclosed","graph1":"Infections and Infectious Diseases","graph2":"Phase I","graph3":"Tigermed","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Injection","sponsorNew":"Tigermed \/ Tigermed","highestDevelopmentStatusID":"6","companyTruncated":"Tigermed \/ Tigermed"},{"orgOrder":0,"company":"Tigermed","sponsor":"Tigermed","pharmaFlowCategory":"DU","therapeuticArea":"Otolaryngology (Ear, Nose, Throat)","country":"ITALY","productType":"Dietary Supplement","year":"2021","type":"Inapplicable","leadProduct":"Pediafl\u00f9","moa":"Undisclosed","graph1":"Otolaryngology (Ear, Nose, Throat)","graph2":"Undisclosed","graph3":"Tigermed","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Otolaryngology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Tigermed \/ Tigermed","highestDevelopmentStatusID":"1","companyTruncated":"Tigermed \/ Tigermed"},{"orgOrder":0,"company":"Tigermed","sponsor":"Tigermed","pharmaFlowCategory":"DU","therapeuticArea":"Sleep","country":"ITALY","productType":"Dietary Supplement","year":"2020","type":"Inapplicable","leadProduct":"Sonidor","moa":"Undisclosed","graph1":"Sleep","graph2":"Undisclosed","graph3":"Tigermed","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Sleep","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Tigermed \/ Tigermed","highestDevelopmentStatusID":"1","companyTruncated":"Tigermed \/ Tigermed"},{"orgOrder":0,"company":"Tigermed","sponsor":"Tigermed","pharmaFlowCategory":"DU","therapeuticArea":"Undisclosed","country":"CHINA","productType":"Undisclosed","year":"2025","type":"Inapplicable","leadProduct":"TL-001","moa":"Undisclosed","graph1":"Undisclosed","graph2":"Phase I","graph3":"Tigermed","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Tigermed \/ Tigermed","highestDevelopmentStatusID":"6","companyTruncated":"Tigermed \/ Tigermed"},{"orgOrder":0,"company":"Tigermed","sponsor":"Tigermed","pharmaFlowCategory":"DU","therapeuticArea":"Undisclosed","country":"CHINA","productType":"Undisclosed","year":"2023","type":"Inapplicable","leadProduct":"VG290131","moa":"Undisclosed","graph1":"Undisclosed","graph2":"Phase I","graph3":"Tigermed","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Tigermed \/ Tigermed","highestDevelopmentStatusID":"6","companyTruncated":"Tigermed \/ Tigermed"}]

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          Luxepack
                          Not Confirmed
                          Luxepack
                          Not Confirmed

                          Details : The agreement aims for a FDA requested 7-day safety and toxicology large animal study of its lead asset SPC-15, an intranasal prophylactic treatment for post-traumatic stress disorder (PTSD).

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Undisclosed

                          May 14, 2025

                          Lead Product(s) : SPC-15

                          Therapeutic Area : Psychiatry/Psychology

                          Highest Development Status : IND Enabling

                          Recipient : Silo Pharma

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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                          02

                          Luxepack
                          Not Confirmed
                          Luxepack
                          Not Confirmed

                          Details : TL-001 is a drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of undefined medical condition.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Inapplicable

                          March 10, 2025

                          Lead Product(s) : TL-001

                          Therapeutic Area : Undisclosed

                          Highest Development Status : Phase I

                          Recipient : TrueLab Biopharmaceutical Co., Ltd

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          Luxepack
                          Not Confirmed
                          Luxepack
                          Not Confirmed

                          Details : Anakinra is a Protein drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Familial Mediterranean Fever.

                          Product Name : Undisclosed

                          Product Type : Protein

                          Upfront Cash : Inapplicable

                          October 30, 2024

                          Lead Product(s) : Anakinra

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase IV

                          Recipient : Swedish Orphan Biovitrum AB

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          Luxepack
                          Not Confirmed
                          Luxepack
                          Not Confirmed

                          Details : JCXH-105 is a Vaccine drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Herpes Zoster.

                          Product Name : Undisclosed

                          Product Type : Vaccine

                          Upfront Cash : Inapplicable

                          September 03, 2024

                          Lead Product(s) : JCXH-105

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Recipient : Immorna

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          Luxepack
                          Not Confirmed
                          Luxepack
                          Not Confirmed

                          Details : JCXH-108 is a Vaccine drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Communicable Diseases.

                          Product Name : Undisclosed

                          Product Type : Vaccine

                          Upfront Cash : Inapplicable

                          August 21, 2024

                          Lead Product(s) : JCXH-108

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase I

                          Recipient : Immorna

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          Luxepack
                          Not Confirmed
                          Luxepack
                          Not Confirmed

                          Details : Ketamir-2, a novel oral ketamine analog, is being evaluated for its potential ultra-rapid antidepressant effects in major depressive disorder with suicidal ideation and treatment-resistant depression.

                          Product Name : Undisclosed

                          Product Type : Controlled Substance

                          Upfront Cash : Inapplicable

                          April 02, 2024

                          Lead Product(s) : Ketamine Hydrochloride

                          Therapeutic Area : Psychiatry/Psychology

                          Highest Development Status : Preclinical

                          Recipient : Mira Pharmaceuticals

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          Luxepack
                          Not Confirmed
                          Luxepack
                          Not Confirmed

                          Details : VG290131 is a drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of undefined medical condition.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Inapplicable

                          October 13, 2023

                          Lead Product(s) : VG290131

                          Therapeutic Area : Undisclosed

                          Highest Development Status : Phase I

                          Recipient : Zhejiang Vimgreen Pharmaceuticals, Ltd.

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          Luxepack
                          Not Confirmed
                          Luxepack
                          Not Confirmed

                          Details : Difelikefalin is a Protein drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Pruritus.

                          Product Name : Undisclosed

                          Product Type : Protein

                          Upfront Cash : Inapplicable

                          June 02, 2023

                          Lead Product(s) : Difelikefalin Acetate

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase III

                          Recipient : CSL Vifor

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          Luxepack
                          Not Confirmed
                          Luxepack
                          Not Confirmed

                          Details : Difelikefalin is a Protein drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Kidney Failure, Chronic.

                          Product Name : Undisclosed

                          Product Type : Protein

                          Upfront Cash : Inapplicable

                          June 02, 2023

                          Lead Product(s) : Difelikefalin Acetate

                          Therapeutic Area : Nephrology

                          Highest Development Status : Phase I

                          Recipient : CSL Vifor

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          Luxepack
                          Not Confirmed
                          Luxepack
                          Not Confirmed

                          Details : Diosmin is a Other Small Molecule drug candidate, which is currently being evaluated in clinical studies for the treatment of Haemorrhoids.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          March 01, 2023

                          Lead Product(s) : Diosmin

                          Therapeutic Area : Gastroenterology

                          Highest Development Status : Undisclosed

                          Recipient : Giellepi S.p.A

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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