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Find Clinical Drug Pipeline Developments & Deals by Third Harmonic Bio
The Company is initiating nonclinical studies to elucidate the mechanism for the observed transaminitis, which was not predicted by extensive GLP toxicology studies of THB001 nor observed in the Company’s Phase 1a study.
THB001, is a highly selective, oral small-molecule inhibitor of KIT, a cell surface receptor that serves as the master regulator of mast cell function and survival.
This financing will fund development of the company’s lead candidate, THB001, through the next phase of human studies for the initial indication of chronic urticaria.