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Diseases","graph2":"Preclinical","graph3":"Themis Bioscience","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Themis Bioscience \/ Merck & Co","highestDevelopmentStatusID":"4","companyTruncated":"Themis Bioscience \/ Merck & Co"},{"orgOrder":0,"company":"Themis Bioscience","sponsor":"Merck & Co","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"AUSTRIA","productType":"Vaccine","year":"2020","type":"Acquisition","leadProduct":"SARS-CoV-2 Vaccine","moa":"SARS-CoV-2 S","graph1":"Infections and Infectious Diseases","graph2":"Preclinical","graph3":"Themis Bioscience","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Themis Bioscience \/ Merck & Co","highestDevelopmentStatusID":"4","companyTruncated":"Themis Bioscience \/ Merck & Co"},{"orgOrder":0,"company":"Themis Bioscience","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"AUSTRIA","productType":"Vaccine","year":"2018","type":"Inapplicable","leadProduct":"Measles Virus-Chikungunya Vaccine","moa":"Undisclosed","graph1":"Infections and Infectious Diseases","graph2":"Phase II","graph3":"Themis Bioscience","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Injection","sponsorNew":"Themis Bioscience \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"Themis Bioscience \/ Undisclosed"},{"orgOrder":0,"company":"Themis Bioscience","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"AUSTRIA","productType":"Virus-drug Conjugate","year":"2016","type":"Inapplicable","leadProduct":"MV-CHIK","moa":"Undisclosed","graph1":"Infections and Infectious Diseases","graph2":"Phase II","graph3":"Themis Bioscience","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Suspension","sponsorNew":"Themis Bioscience \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"Themis Bioscience \/ Undisclosed"},{"orgOrder":0,"company":"Themis Bioscience","sponsor":"Walter Reed Army Institute of Research","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"AUSTRIA","productType":"Virus-drug Conjugate","year":"2017","type":"Inapplicable","leadProduct":"MV-CHIK","moa":"Undisclosed","graph1":"Infections and Infectious Diseases","graph2":"Phase II","graph3":"Themis Bioscience","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Suspension","sponsorNew":"Themis Bioscience \/ Walter Reed Army Institute of 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Diseases","graph2":"Phase I","graph3":"Themis Bioscience","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Themis Bioscience \/ Undisclosed","highestDevelopmentStatusID":"6","companyTruncated":"Themis Bioscience \/ Undisclosed"},{"orgOrder":0,"company":"Themis Bioscience","sponsor":"Assign Data Management and Biostatistics | Optimapharm","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"AUSTRIA","productType":"Undisclosed","year":"2019","type":"Inapplicable","leadProduct":"TMV-018","moa":"Undisclosed","graph1":"Oncology","graph2":"Phase I","graph3":"Themis Bioscience","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Liquid","sponsorNew":"Themis Bioscience \/ Assign Data Management and Biostatistics | Optimapharm","highestDevelopmentStatusID":"6","companyTruncated":"Themis Bioscience \/ Assign Data Management and Biostatistics | Optimapharm"},{"orgOrder":0,"company":"Themis Bioscience","sponsor":"Walter Reed Army Institute of Research","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"AUSTRIA","productType":"Undisclosed","year":"2019","type":"Inapplicable","leadProduct":"V184","moa":"Undisclosed","graph1":"Infections and Infectious Diseases","graph2":"Phase II","graph3":"Themis Bioscience","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Injection","sponsorNew":"Themis Bioscience \/ Walter Reed Army Institute of Research","highestDevelopmentStatusID":"8","companyTruncated":"Themis Bioscience \/ Walter Reed Army Institute of Research"},{"orgOrder":0,"company":"Themis Bioscience","sponsor":"Themis Bioscience","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious 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Find Clinical Drug Pipeline Developments & Deals by Themis Bioscience

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                          Top Deals by Deal Size (USD bn)

                          01

                          AIChE Annual Meeting
                          Not Confirmed
                          AIChE Annual Meeting
                          Not Confirmed

                          Details : An initial focus of this agreement is acceleration of the development of a measles vector-based SARS-CoV-2 vaccine candidate. This candidate is currently in pre-clinical development, and clinical studies are planned to start later in 2020.

                          Product Name : Undisclosed

                          Product Type : Vaccine

                          Upfront Cash : Undisclosed

                          June 19, 2020

                          Lead Product(s) : SARS-CoV-2 Vaccine

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Preclinical

                          Sponsor : Merck & Co

                          Deal Size : Undisclosed

                          Deal Type : Acquisition

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                          02

                          AIChE Annual Meeting
                          Not Confirmed
                          AIChE Annual Meeting
                          Not Confirmed

                          Details : The planned acquisition builds upon an ongoing collaboration between the two companies to develop vaccine candidates using the measles virus vector platform, and is expected to accelerate the development of Themis’ COVID-19 vaccine candidate.

                          Product Name : Undisclosed

                          Product Type : Vaccine

                          Upfront Cash : Undisclosed

                          May 26, 2020

                          Lead Product(s) : SARS-CoV-2 Vaccine

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Undisclosed

                          Sponsor : Merck & Co

                          Deal Size : Undisclosed

                          Deal Type : Acquisition

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                          03

                          AIChE Annual Meeting
                          Not Confirmed
                          AIChE Annual Meeting
                          Not Confirmed

                          Details : The development of MV-SARS-CoV-2 is being conducted in partnership with the Austrian biotech company Thémis, which is responsible for the production of preclinical and, clinical batches.

                          Product Name : Undisclosed

                          Product Type : Vaccine

                          Upfront Cash : Inapplicable

                          May 26, 2020

                          Lead Product(s) : MV-SARS-CoV-2

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Preclinical

                          Recipient : Institut Pasteur

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          AIChE Annual Meeting
                          Not Confirmed
                          AIChE Annual Meeting
                          Not Confirmed

                          Details : Themis and ABL Europe have signed an agreement under which ABL will manufacture Themis' vaccine candidate in preparation for clinical trials.

                          Product Name : Undisclosed

                          Product Type : Vaccine

                          Upfront Cash : Undisclosed

                          May 11, 2020

                          Lead Product(s) : COVID-19 Vaccine

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Undisclosed

                          Recipient : ABL Bio

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          05

                          AIChE Annual Meeting
                          Not Confirmed
                          AIChE Annual Meeting
                          Not Confirmed

                          Lead Product(s) : TMV-018

                          Therapeutic Area : Oncology

                          Study Phase : Phase I

                          Sponsor : Assign Data Management and Biostatistics | Optimapharm

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : TMV-018 is a drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Gastrointestinal Neoplasms.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Inapplicable

                          December 11, 2019

                          Lead Product(s) : TMV-018

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Assign Data Management and Biostatistics | Optimapharm

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          AIChE Annual Meeting
                          Not Confirmed
                          AIChE Annual Meeting
                          Not Confirmed

                          Lead Product(s) : MV-LASV vaccine

                          Therapeutic Area : Infections and Infectious Diseases

                          Study Phase : Phase I

                          Sponsor : Coalition for Epidemic Preparedness Innovations | Harmony Clinical Research | Assign Data Management and Biostatistics

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : MV-LASV vaccine is a Vaccine drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Lassa Fever.

                          Product Name : Undisclosed

                          Product Type : Vaccine

                          Upfront Cash : Inapplicable

                          August 13, 2019

                          Lead Product(s) : MV-LASV vaccine

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase I

                          Sponsor : Coalition for Epidemic Preparedness Innovations | Harmony Clinical Research | Assign Data Management and Biostatistics

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          AIChE Annual Meeting
                          Not Confirmed
                          AIChE Annual Meeting
                          Not Confirmed

                          Details : MV-ZIKA-RSP Vaccine is a Vaccine drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Zika Virus Infection.

                          Product Name : Undisclosed

                          Product Type : Vaccine

                          Upfront Cash : Inapplicable

                          July 25, 2019

                          Lead Product(s) : MV-ZIKA-RSP Vaccine

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase I

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          AIChE Annual Meeting
                          Not Confirmed
                          AIChE Annual Meeting
                          Not Confirmed

                          Details : V184 is a drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Chikungunya Fever.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Inapplicable

                          January 17, 2019

                          Lead Product(s) : V184

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Sponsor : Walter Reed Army Institute of Research

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          AIChE Annual Meeting
                          Not Confirmed
                          AIChE Annual Meeting
                          Not Confirmed

                          Details : MV-CHIK Vaccine (Measles Virus-Chikungunya Vaccine) is a Vaccine drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Chikungunya Fever.

                          Product Name : MV-CHIK Vaccine

                          Product Type : Vaccine

                          Upfront Cash : Inapplicable

                          August 17, 2018

                          Lead Product(s) : Measles Virus-Chikungunya Vaccine

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          AIChE Annual Meeting
                          Not Confirmed
                          AIChE Annual Meeting
                          Not Confirmed

                          Details : MV-CHIK is a Virus-drug Conjugate drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Chikungunya Fever.

                          Product Name : Undisclosed

                          Product Type : Virus-drug Conjugate

                          Upfront Cash : Inapplicable

                          April 04, 2017

                          Lead Product(s) : MV-CHIK

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Sponsor : Walter Reed Army Institute of Research

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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