[{"orgOrder":0,"company":"Lexicon pharmaceuticals","sponsor":"Not Applicable","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not Applicable","newsHeadline":"Lexicon Pharmaceuticals Announces Topline Phase 3 Data From Four Phase 3 Sotagliflozin Studies In Type 2 Diabetes","therapeuticArea":"Endocrinology","highestDevelopmentStatus":"Phase III","country":"U.S.A","productType":"Small molecule","productStatus":"Approved","date":"July 2020","url1":"","url2":"","graph1":"Endocrinology","graph2":"Phase III"},{"orgOrder":0,"company":"Lexicon pharmaceuticals","sponsor":"Not Applicable","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not Applicable","newsHeadline":"Results From SOLOIST and SCORED Outcomes Studies Presented at the AHA Scientific Sessions and Published in the NEJM","therapeuticArea":"Endocrinology","highestDevelopmentStatus":"Phase III","country":"U.S.A","productType":"Small molecule","productStatus":"Approved","date":"November 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III"},{"orgOrder":0,"company":"Lexicon pharmaceuticals","sponsor":"Not Applicable","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not Applicable","newsHeadline":"New Analysis of SOLOIST-WHF Results Demonstrates Sotagliflozin\u2019s Significant Effect in Reducing the Risk of Hospital Readmissions for Heart Failure","therapeuticArea":"Cardiology\/Vascular Diseases","highestDevelopmentStatus":"Phase III","country":"U.S.A","productType":"Small molecule","productStatus":"Approved","date":"November 2022","url1":"","url2":"","graph1":"Cardiology\/Vascular Diseases","graph2":"Phase III"},{"orgOrder":0,"company":"Lexicon pharmaceuticals","sponsor":"Not Applicable","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not Applicable","newsHeadline":"New Analyses of Sotagliflozin Showing Time to Clinical Benefit Presented at The American College of Cardiology\u2019s 72nd Annual Scientific Session Together With World Heart Federation\u2019s World Congress of Cardiology","therapeuticArea":"Cardiology\/Vascular Diseases","highestDevelopmentStatus":"Phase III","country":"U.S.A","productType":"Small molecule","productStatus":"Approved","date":"March 2023","url1":"","url2":"","graph1":"Cardiology\/Vascular Diseases","graph2":"Phase III"},{"orgOrder":0,"company":"Lexicon pharmaceuticals","sponsor":"Not Applicable","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not Applicable","newsHeadline":"Lexicon Announces FDA Approval of INPEFA\u2122 (sotagliflozin) for Treatment of Heart Failure","therapeuticArea":"Cardiology\/Vascular Diseases","highestDevelopmentStatus":"Approved","country":"U.S.A","productType":"Small molecule","productStatus":"Approved","date":"May 2023","url1":"","url2":"","graph1":"Cardiology\/Vascular Diseases","graph2":"Approved"},{"orgOrder":0,"company":"Lexicon pharmaceuticals","sponsor":"Not Applicable","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not Applicable","newsHeadline":"Lexicon Announces FDA Approval of INPEFA (sotagliflozin) for Treatment of Heart Failure","therapeuticArea":"Cardiology\/Vascular Diseases","highestDevelopmentStatus":"Approved","country":"U.S.A","productType":"Small molecule","productStatus":"Approved","date":"June 2023","url1":"","url2":"","graph1":"Cardiology\/Vascular Diseases","graph2":"Approved"},{"orgOrder":0,"company":"Lexicon pharmaceuticals","sponsor":"Sanofi","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not Applicable","newsHeadline":"Lexicon Preparing to Resubmit Sotagliflozin NDA for Type 1 Diabetes Following Feedback From FDA","therapeuticArea":"Endocrinology","highestDevelopmentStatus":"Phase III","country":"U.S.A","productType":"Small molecule","productStatus":"Approved","date":"March 2024","url1":"","url2":"","graph1":"Endocrinology","graph2":"Phase III"},{"orgOrder":0,"company":"Lexicon pharmaceuticals","sponsor":"Not Applicable","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not 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Find Clinical Drug Pipeline Developments & Deals for Sotagliflozin
Lexicon lead product Inpefa (sotagliflozin), SGLT2/SGLT1 inhibitor. Currently, it is being evaluated in the Phase III clinical trial studies with patients for the treatment of Diabetes Mellitus Type 1 and chronic kidney failure.
Inpefa (sotagliflozin) is a small molecule dual inhibitor of SGLT1 and SGLT2, which is being evaluated for the treatment of type 1 diabetes and chronic kidney disease.
INPEFA (sotagliflozin) is an oral Tablet inhibitor of two proteins responsible for glucose regulation known as SGLT2 and SGLT1 and reduce the risk of cardiovascular death, hospitalization for heart failure.
Lexicon intends to use the proceeds from the public offering to fund the commercial launch of FDA approved, Inpefa (sotagliflozin), an orally-delivered small molecule, a sodium-glucose cotransporter type 2 inhibitor that also inhibits SGLT1, for the treatment of heart failure.
Lexicon intends to use the proceeds to fund the commercial launch of Inpefa (sotagliflozin), an inhibitor of SGLT2 and SGLT1 approved for the treatment of heart failure, and to fund the continued research and development of its drug candidates.
Lexicon currently intends to use the net proceeds to fund the commercial launch of Inpefa (sotagliflozin), an inhibitor of SGLT2 and SGLT1, recently approved by FDA for the treatment of heart failure.
INPEFA™ (sotagliflozin) is an oral Tablet inhibitor of two proteins responsible for glucose regulation known as SGLT2 and SGLT1 and reduce the risk of cardiovascular death, hospitalization for heart failure.
SAR439954 (sotagliflozin) is an oral dual inhibitor of two proteins responsible for glucose regulation known as SGLT1 and SGLT2. SGLT1 is responsible for glucose absorption in the gastrointestinal tract, and SGLT2 is responsible for glucose reabsorption by the kidney.
Treatment with sotagliflozin (SAR439954) demonstrated significant relative risk reductions for non-fatal heart failure events and for the composite of cardiovascular death and readmission for heart failure at 30 or 90 days following hospital discharge versus placebo.
SAR439954 (sotagliflozin) is an investigational oral dual inhibitor of two proteins responsible for glucose regulation known as SGLT1 and SGLT2. SGLT1 is responsible for glucose absorption in the GI tract, and SGLT2 is responsible for glucose reabsorption by the kidney.
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