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    [{"orgOrder":0,"company":"SFJ Pharmaceuticals","sponsor":"Apellis Pharmaceuticals","pharmaFlowCategory":"DU","therapeuticArea":"Rare Diseases and Disorders","country":"U.S.A","productType":"Peptide, Unconjugated","year":"2021","type":"Inapplicable","leadProduct":"Pegcetacoplan","moa":"Complement C3","graph1":"Rare Diseases and Disorders","graph2":"Approved FDF","graph3":"SFJ Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Rare Diseases","amount2New":0,"dosageForm":"Injection","sponsorNew":"SFJ Pharmaceuticals \/ SFJ Pharmaceuticals","highestDevelopmentStatusID":"15","companyTruncated":"SFJ Pharmaceuticals \/ SFJ Pharmaceuticals"},{"orgOrder":0,"company":"SFJ Pharmaceuticals","sponsor":"SFJ Pharmaceuticals | Merck Group | AIO-Studien-gGmbH | Academic and Community Cancer Research United","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Antibody, 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    Find Clinical Drug Pipeline Developments & Deals by SFJ Pharmaceuticals

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                            01

                            SFJ Pharmaceuticals

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                            Lead Product(s) : Bentracimab

                            Therapeutic Area : Hematology

                            Study Phase : Phase III

                            Sponsor : Serb

                            Deal Size : Undisclosed

                            Deal Type : Partnership

                            DEALS_DEV arrow-down

                            SERB Pharmaceuticals and SFJ Pharmaceuticals Announce a U.S. Partnership for Bentracimab, a Ticagrelor

                            Details : Through the acquisition, SERB has acquired exclusive US rights to the ticagrelor reversal agent PB2452 (bentracimab), a novel, monoclonal antibody fragment, from SFJ. SFJ will remain responsible for the ongoing trials of bentracimab and will work with SE...

                            Product Name : Undisclosed

                            Product Type : Antibody, Unconjugated

                            Upfront Cash : Undisclosed

                            May 11, 2023

                            Lead Product(s) : Bentracimab

                            Therapeutic Area : Hematology

                            Highest Development Status : Phase III

                            Sponsor : Serb

                            Deal Size : Undisclosed

                            Deal Type : Partnership

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                            02

                            SFJ Pharmaceuticals

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                            AIChE Annual Meeting
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                            SFJ Pharmaceuticals

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                            AIChE Annual Meeting
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                            Lead Product(s) : Bentracimab

                            Therapeutic Area : Hematology

                            Study Phase : Phase III

                            Recipient : PhaseBio Pharmaceuticals

                            Deal Size : $120.0 million

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            SFJ Pharmaceuticals Announces Closing of Transfer of Bentracimab Assets from PhaseBio Pharmaceuticals

                            Details : PB2452 (bentracimab) is a novel, recombinant, human monoclonal antibody antigen-binding fragment designed to reverse the antiplatelet activity of ticagrelor in major bleeding and urgent surgery situations.

                            Product Name : Undisclosed

                            Product Type : Antibody, Unconjugated

                            Upfront Cash : Undisclosed

                            January 17, 2023

                            Lead Product(s) : Bentracimab

                            Therapeutic Area : Hematology

                            Highest Development Status : Phase III

                            Recipient : PhaseBio Pharmaceuticals

                            Deal Size : $120.0 million

                            Deal Type : Collaboration

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                            03

                            SFJ Pharmaceuticals

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                            AIChE Annual Meeting
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                            Lead Product(s) : Bentracimab

                            Therapeutic Area : Undisclosed

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Study to Evaluate the Safety, Tolerability, PK, and PD of PB2452 With and Without Ticagrelor Pretreatment in C...

                            Details : Bentracimab is a Antibody drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of undefined medical condition.

                            Product Name : Undisclosed

                            Product Type : Antibody, Unconjugated

                            Upfront Cash : Inapplicable

                            December 17, 2021

                            Lead Product(s) : Bentracimab

                            Therapeutic Area : Undisclosed

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            SFJ Pharmaceuticals

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                            AIChE Annual Meeting
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                            SFJ Pharmaceuticals

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                            AIChE Annual Meeting
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                            Lead Product(s) : Pegcetacoplan

                            Therapeutic Area : Rare Diseases and Disorders

                            Study Phase : Phase IV

                            Recipient : Apellis Pharmaceuticals

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Apellis to Present Long-Term Pegcetacoplan Data in PNH at the European Hematology Association Virtual Congress

                            Details : In the study, EMPAVELI met the primary endpoint, demonstrating superiority to Soliris for the change from baseline in hemoglobin level at Week 16 with an adjusted mean increase of 3.84 g/dL of hemoglobin.

                            Product Name : Empaveli

                            Product Type : Peptide, Unconjugated

                            Upfront Cash : Inapplicable

                            May 14, 2021

                            Lead Product(s) : Pegcetacoplan

                            Therapeutic Area : Rare Diseases and Disorders

                            Highest Development Status : Phase IV

                            Recipient : Apellis Pharmaceuticals

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            SFJ Pharmaceuticals

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                            AIChE Annual Meeting
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                            AIChE Annual Meeting
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                            Lead Product(s) : Bempegaldesleukin,Pembrolizumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Recipient : Nektar Therapeutics

                            Deal Size : $150.0 million

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Nektar Announces Collaboration with SFJ Pharmaceuticals® for Bempegaldesleukin in Head and Neck Cancer

                            Details : The collaboration between SFJ and Nektar will support a new Phase 2/3 registrational clinical study of BEMPEG plus pembrolizumab in patients with head and neck cancer whose tumors express PD-L1 (Combined Positive Score).

                            Product Name : Bempeg

                            Product Type : Protein

                            Upfront Cash : Undisclosed

                            February 17, 2021

                            Lead Product(s) : Bempegaldesleukin,Pembrolizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Recipient : Nektar Therapeutics

                            Deal Size : $150.0 million

                            Deal Type : Collaboration

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                            06

                            SFJ Pharmaceuticals

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                            AIChE Annual Meeting
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                            Lead Product(s) : Bentracimab

                            Therapeutic Area : Hematology

                            Study Phase : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Bentracimab in Ticagrelor-treated Patients With Uncontrolled Bleeding or Requiring Urgent Surgery or Invasive ...

                            Details : Bentracimab is a Antibody drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Hemorrhage.

                            Product Name : Undisclosed

                            Product Type : Antibody, Unconjugated

                            Upfront Cash : Inapplicable

                            February 27, 2020

                            Lead Product(s) : Bentracimab

                            Therapeutic Area : Hematology

                            Highest Development Status : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            SFJ Pharmaceuticals

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                            AIChE Annual Meeting
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                            SFJ Pharmaceuticals

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                            AIChE Annual Meeting
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                            Lead Product(s) : Bentracimab

                            Therapeutic Area : Hematology

                            Study Phase : Phase II

                            Recipient : PhaseBio Pharmaceuticals

                            Deal Size : $120.0 million

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            PhaseBio Announces Financing and Co-Development Collaboration with SFJ Pharmaceuticals® for PB2452

                            Details : The collaboration with SFJ provides PhaseBio with substantial funding to continue the rapid advancement of lead program, PB2452.

                            Product Name : Undisclosed

                            Product Type : Antibody, Unconjugated

                            Upfront Cash : Undisclosed

                            January 10, 2020

                            Lead Product(s) : Bentracimab

                            Therapeutic Area : Hematology

                            Highest Development Status : Phase II

                            Recipient : PhaseBio Pharmaceuticals

                            Deal Size : $120.0 million

                            Deal Type : Collaboration

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                            08

                            SFJ Pharmaceuticals

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                            AIChE Annual Meeting
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                            SFJ Pharmaceuticals

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                            Lead Product(s) : Ticagrelor

                            Therapeutic Area : Undisclosed

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Phase 2B Study to Evaluate the Efficacy of Bentracimab (PB2452) in Reversal of Ticagrelor in Subjects Aged 50-...

                            Details : Ticagrelor is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of undefined medical condition.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            October 10, 2019

                            Lead Product(s) : Ticagrelor

                            Therapeutic Area : Undisclosed

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            SFJ Pharmaceuticals

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                            AIChE Annual Meeting
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                            SFJ Pharmaceuticals

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                            Lead Product(s) : Ticagrelor

                            Therapeutic Area : Undisclosed

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Study to Evaluate the Safety, Tolerability, PK and PD of PB2452 in Healthy Younger, Older and Elderly Subjects

                            Details : Ticagrelor is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of undefined medical condition.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            April 26, 2019

                            Lead Product(s) : Ticagrelor

                            Therapeutic Area : Undisclosed

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            SFJ Pharmaceuticals

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                            AIChE Annual Meeting
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                            Lead Product(s) : Abituzumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : SFJ Pharmaceuticals | Merck Group | AIO-Studien-gGmbH | Academic and Community Cancer Research United

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Study of Abituzumab in Combination With Cetuximab and FOLFIRI in Patients With Metastatic Colorectal Cancer.

                            Details : Abituzumab is a Antibody drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Colorectal Neoplasms.

                            Product Name : Undisclosed

                            Product Type : Antibody, Unconjugated

                            Upfront Cash : Inapplicable

                            September 28, 2018

                            Lead Product(s) : Abituzumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : SFJ Pharmaceuticals | Merck Group | AIO-Studien-gGmbH | Academic and Community Cancer Research United

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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