Lead Product(s) : Senaparib
Therapeutic Area : Oncology
Study Phase : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Senaparib Approved by NMPA for 1L Maintenance Therapy in Ovarian Cancer
Details : Paxonin (senaparib) is a PARP 1/2 inhibitor, received NMPA approval as monotherapy for adult patients with advanced epithelial (FIGO Stages III and IV) high-grade ovarian cancer.
Product Name : Paxonin
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
January 16, 2025
Lead Product(s) : Senaparib
Therapeutic Area : Oncology
Highest Development Status : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : IMP4927 (senaparib) is a PARP inhibitor, being investigated as monotherapy maintenance treatment following first-line platinum-based chemotherapy in patients with FIGO stage III/IV ovarian cancer who have achieved complete response or partial response.
Product Name : IMP4927
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
December 04, 2023
Lead Product(s) : Senaparib,Temozolomide
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
FDA Granted Orphan Drug Designation to IMP4297+TMZ for SCLC
Details : The preliminary clinical results for a phase I b/II study investigating the PARP inhibitor IMP4297 having Senaparib in combination with temozolomide (TMZ) for the treatment of advanced solid tumors.
Product Name : IMP4297
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
August 19, 2022
Lead Product(s) : Senaparib,Temozolomide
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Impact Therapeutics Announces Completion of Series D1 Financing
Details : Proceeds will be used to accelerate the development of its synthetic lethality programs, including IMP4297, which are showing best-in-class potential. The company already has three synthetic lethality compounds in the clinical stage.
Product Name : IMP4297
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
March 14, 2022
Lead Product(s) : IMP9064,Senaparib
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Burning Rock Dx
Deal Size : Undisclosed
Deal Type : Collaboration
Details : Under the collaboration, Burning Rock will provide the testing services in connection with IMPACT Therapeutics’ development of its ATR inhibitor IMP9064, with worldwide intellectual property rights.
Product Name : IMP9064
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
April 11, 2021
Lead Product(s) : IMP9064,Senaparib
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Burning Rock Dx
Deal Size : Undisclosed
Deal Type : Collaboration