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    [{"orgOrder":0,"company":"Secura Bio","sponsor":"Moffitt Cancer Center","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cytotoxic Drug","year":"2021","type":"Inapplicable","leadProduct":"BMS-986345","moa":"DNMT1","graph1":"Oncology","graph2":"Phase I","graph3":"Secura Bio","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Secura Bio \/ Secura Bio","highestDevelopmentStatusID":"6","companyTruncated":"Secura Bio \/ Secura Bio"},{"orgOrder":0,"company":"Secura Bio","sponsor":"Dana-Farber Cancer Institute","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Miscellaneous","year":"2014","type":"Inapplicable","leadProduct":"Duvelisib","moa":"PI3-kinase p110-gamma subunit | PI3-kinase p110-delta subunit","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Secura Bio","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Secura Bio \/ Secura Bio","highestDevelopmentStatusID":"7","companyTruncated":"Secura Bio \/ Secura Bio"},{"orgOrder":0,"company":"Secura Bio","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Miscellaneous","year":"2021","type":"Inapplicable","leadProduct":"Duvelisib","moa":"PI3-kinase p110-gamma subunit | PI3-kinase p110-delta subunit","graph1":"Oncology","graph2":"Approved FDF","graph3":"Secura Bio","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Capsule","sponsorNew":"Secura Bio \/ Undisclosed","highestDevelopmentStatusID":"15","companyTruncated":"Secura Bio \/ Undisclosed"},{"orgOrder":0,"company":"Secura Bio","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Miscellaneous","year":"2023","type":"Inapplicable","leadProduct":"Duvelisib","moa":"PI3-kinase p110-gamma subunit | PI3-kinase p110-delta subunit","graph1":"Oncology","graph2":"Phase II","graph3":"Secura Bio","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Capsule","sponsorNew":"Secura Bio \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"Secura Bio \/ Undisclosed"},{"orgOrder":0,"company":"Secura Bio","sponsor":"Dana-Farber Cancer Institute","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Miscellaneous","year":"2018","type":"Inapplicable","leadProduct":"Duvelisib","moa":"PI3-kinase p110-gamma subunit | PI3-kinase p110-delta subunit","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Secura Bio","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Secura Bio \/ Secura Bio","highestDevelopmentStatusID":"7","companyTruncated":"Secura Bio \/ Secura Bio"},{"orgOrder":0,"company":"Secura Bio","sponsor":"Verastem Oncology","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Miscellaneous","year":"2020","type":"Divestment","leadProduct":"Duvelisib","moa":"PI3-kinase p110-gamma subunit | PI3-kinase p110-delta subunit","graph1":"Oncology","graph2":"Approved FDF","graph3":"Secura Bio","amount2":0.31,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Oncology","amount2New":0.47999999999999998,"dosageForm":"Undisclosed","sponsorNew":"Secura Bio \/ Secura Bio","highestDevelopmentStatusID":"15","companyTruncated":"Secura Bio \/ Secura Bio"},{"orgOrder":0,"company":"Secura Bio","sponsor":"Verastem Oncology","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Miscellaneous","year":"2020","type":"Divestment","leadProduct":"Duvelisib","moa":"PI3-kinase p110-gamma subunit | PI3-kinase p110-delta subunit","graph1":"Oncology","graph2":"Approved FDF","graph3":"Secura Bio","amount2":0.47999999999999998,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Oncology","amount2New":0.47999999999999998,"dosageForm":"Undisclosed","sponsorNew":"Secura Bio \/ Secura Bio","highestDevelopmentStatusID":"15","companyTruncated":"Secura Bio \/ Secura Bio"},{"orgOrder":0,"company":"Secura Bio","sponsor":"Abdullah Kutlar","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Miscellaneous","year":"2010","type":"Inapplicable","leadProduct":"Panobinostat lactate","moa":"Histone deacetylase","graph1":"Genetic Disease","graph2":"Phase I","graph3":"Secura Bio","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Capsule","sponsorNew":"Secura Bio \/ Abdullah Kutlar","highestDevelopmentStatusID":"6","companyTruncated":"Secura Bio \/ Abdullah Kutlar"},{"orgOrder":0,"company":"Secura Bio","sponsor":"Glenn J. Hanna","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Miscellaneous","year":"2021","type":"Inapplicable","leadProduct":"Duvelisib","moa":"PI3-kinase p110-gamma subunit | PI3-kinase p110-delta subunit","graph1":"Oncology","graph2":"Phase II","graph3":"Secura Bio","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Capsule","sponsorNew":"Secura Bio \/ Glenn J. Hanna","highestDevelopmentStatusID":"8","companyTruncated":"Secura Bio \/ Glenn J. Hanna"},{"orgOrder":0,"company":"Secura Bio","sponsor":"John Kirkwood","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Antibody, Unconjugated","year":"2020","type":"Inapplicable","leadProduct":"Nivolumab","moa":"Programmed cell death protein 1","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Secura Bio","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Secura Bio \/ John Kirkwood","highestDevelopmentStatusID":"7","companyTruncated":"Secura Bio \/ John Kirkwood"}]

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                            01

                            Secura Bio

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                            AIChE Annual Meeting
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                            Lead Product(s) : Duvelisib

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Secura Bio, Inc. Receives Orphan Drug Designation in Europe for Duvelisib for the Treatment of Patients with P...

                            Details : COPIKTRA (duvelisib) is an oral inhibitor of phosphoinositide 3-kinase (PI3K), and the first US approved dual inhibitor of PI3K-delta and PI3K-gamma, two enzymes known to help support the growth and survival of malignant cells.

                            Product Name : Copiktra

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            January 09, 2023

                            Lead Product(s) : Duvelisib

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Secura Bio

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                            AIChE Annual Meeting
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                            AIChE Annual Meeting
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                            Lead Product(s) : BMS-986345

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Recipient : Moffitt Cancer Center

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Duvelisib in Combination With BMS-986345 in Lymphoid Malignancy

                            Details : BMS-986345 is a Cytotoxic Drug drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Lymphoma, Non-Hodgkin.

                            Product Name : Undisclosed

                            Product Type : Cytotoxic Drug

                            Upfront Cash : Inapplicable

                            October 04, 2021

                            Lead Product(s) : BMS-986345

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Recipient : Moffitt Cancer Center

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Secura Bio

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                            AIChE Annual Meeting
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                            AIChE Annual Meeting
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                            Lead Product(s) : Duvelisib

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Glenn J. Hanna

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Duvelisib Plus Docetaxel In Recurrent/Metastatic HNSCC

                            Details : Duvelisib is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Squamous Cell Carcinoma of Head and Neck.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            September 27, 2021

                            Lead Product(s) : Duvelisib

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Glenn J. Hanna

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Secura Bio

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                            AIChE Annual Meeting
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                            AIChE Annual Meeting
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                            Lead Product(s) : Duvelisib

                            Therapeutic Area : Oncology

                            Study Phase : Approved FDF

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Secura Bio's COPIKTRA® Receives Positive CHMP Opinion for the Treatment of Relapsed and Refractory CLL and Re...

                            Details : COPIKTRA is an oral dual inhibitor of the PI3K-delta and gamma pathways, which are involved in the proliferation, growth, and migration of malignant cells and are thought to play a role in the formation and maintenance of a supportive tumor microenvironm...

                            Product Name : Copiktra

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            April 01, 2021

                            Lead Product(s) : Duvelisib

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved FDF

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Secura Bio

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                            AIChE Annual Meeting
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                            AIChE Annual Meeting
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                            Lead Product(s) : Nivolumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : John Kirkwood

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Duvelisib in Combination With Nivolumab in Patients With Advanced Unresectable Melanoma

                            Details : Nivolumab is a Antibody drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of Melanoma.

                            Product Name : Undisclosed

                            Product Type : Antibody, Unconjugated

                            Upfront Cash : Inapplicable

                            December 30, 2020

                            Lead Product(s) : Nivolumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : John Kirkwood

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Secura Bio

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                            AIChE Annual Meeting
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                            Lead Product(s) : Duvelisib

                            Therapeutic Area : Oncology

                            Study Phase : Approved FDF

                            Recipient : Verastem Oncology

                            Deal Size : $481.0 million

                            Deal Type : Divestment

                            DEALS_DEV arrow-down

                            Verastem Oncology Announces Closing of COPIKTRA® (duvelisib) Sale to Secura Bio

                            Details : Verastem’s sale of COPIKTRA to Secura Bio follows Verastem’s previously announced new strategic direction focused on development of its RAF/MEK inhibitor (VS-6766) and FAK inhibitor (defactinib) program in KRAS mutant (KRASmt) solid tumors.

                            Product Name : Copiktra

                            Product Type : Miscellaneous

                            Upfront Cash : $70.0 million

                            September 30, 2020

                            Lead Product(s) : Duvelisib

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved FDF

                            Recipient : Verastem Oncology

                            Deal Size : $481.0 million

                            Deal Type : Divestment

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                            07

                            Secura Bio

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                            AIChE Annual Meeting
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                            AIChE Annual Meeting
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                            Lead Product(s) : Duvelisib

                            Therapeutic Area : Oncology

                            Study Phase : Approved FDF

                            Recipient : Verastem Oncology

                            Deal Size : $311.0 million

                            Deal Type : Divestment

                            DEALS_DEV arrow-down

                            Verastem Oncology Signs Definitive Agreement to Sell COPIKTRA® (duvelisib) Rights to Secura Bio

                            Details : Verastem’s sale of COPIKTRA follows the Company’s previously announced strategic direction to focus on maximizing the broad potential of its RAF/MEK inhibitor (VS-6766) and FAK inhibitor (defactinib) program in KRAS mutant (KRASmt) solid tumors.

                            Product Name : Copiktra

                            Product Type : Miscellaneous

                            Upfront Cash : $70.0 million

                            August 10, 2020

                            Lead Product(s) : Duvelisib

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved FDF

                            Recipient : Verastem Oncology

                            Deal Size : $311.0 million

                            Deal Type : Divestment

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                            08

                            Secura Bio

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                            AIChE Annual Meeting
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                            Secura Bio

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                            Lead Product(s) : Duvelisib

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Recipient : Dana-Farber Cancer Institute

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Duvelisib and Venetoclax in Relapsed or Refractory CLL or SLL or RS

                            Details : Duvelisib is a Other Small Molecule drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of Leukemia, Lymphocytic, Chronic, B-Cell.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            May 23, 2018

                            Lead Product(s) : Duvelisib

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Recipient : Dana-Farber Cancer Institute

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Secura Bio

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                            AIChE Annual Meeting
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                            Secura Bio

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                            AIChE Annual Meeting
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                            Lead Product(s) : Duvelisib

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Recipient : Dana-Farber Cancer Institute

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Phase 1b/2 Study of IPI-145 Plus FCR in Previously Untreated, Younger Patients With CLL

                            Details : IPI-145 is a Other Small Molecule drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of Leukemia, Lymphocytic, Chronic, B-Cell.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            June 06, 2014

                            Lead Product(s) : Duvelisib

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Recipient : Dana-Farber Cancer Institute

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Secura Bio

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                            AIChE Annual Meeting
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                            AIChE Annual Meeting
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                            Lead Product(s) : Panobinostat lactate

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase I

                            Sponsor : Abdullah Kutlar

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Study of Panobinostat (LBH589) in Patients With Sickle Cell Disease

                            Details : Panobinostat is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Anemia, Sickle Cell.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            November 22, 2010

                            Lead Product(s) : Panobinostat lactate

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase I

                            Sponsor : Abdullah Kutlar

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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