Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : PSIL-006
Therapeutic Area : Neurology
Study Phase : Preclinical
Recipient : Hesperos
Deal Size : Undisclosed
Deal Type : Collaboration
Psilera Collaborates with Drug Development Leader Hesperos to Advance PSIL-006
Details : The collaboration aims to accelerate the preclinical development of Psilera's lead compound, PSIL-006, targeting frontotemporal dementia (FTD).
Product Name : PSIL-006
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
June 09, 2025
Lead Product(s) : PSIL-006
Therapeutic Area : Neurology
Highest Development Status : Preclinical
Recipient : Hesperos
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : PSIL-006
Therapeutic Area : Psychiatry/Psychology
Study Phase : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Psilera Unveils Novel, Non-Hallucinogenic Psilocybin Derivative PSIL-006 As Lead Clinical Candidate
Details : PSIL-006 is a non-hallucinogenic serotonin receptor 6 (5-HT6) and 2A (5-HT2A) dual agonist that selectively reduces hallucinogenic effects while retaining rapid therapeutic benefits.
Product Name : PSIL-006
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
May 25, 2023
Lead Product(s) : PSIL-006
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Dimethyltryptamine
Therapeutic Area : Psychiatry/Psychology
Study Phase : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : PSIL-001 (N,N-Dimethyltryptamine) and PSIL-002 showed similar preclinical efficacy to psilacetin, a positive control, in the forced swim test depression model without hallucinations via the head twitch response.
Product Name : PSIL-001
Product Type : Controlled Substance
Upfront Cash : Inapplicable
October 08, 2022
Lead Product(s) : Dimethyltryptamine
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Dimethyltryptamine
Therapeutic Area : Neurology
Study Phase : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Psilera Receives First Patent Allowance for Transdermal Patch Formulations
Details : N,N-dimethyltryptamine and psilocybin-like prodrug, psilacetin, patch formulations are designed for patient comfort and useability. The patch design could provide a non-invasive and dose-controlled method of treatment for substance use disorders, PTSD an...
Product Name : PSIL-001
Product Type : Controlled Substance
Upfront Cash : Inapplicable
September 14, 2022
Lead Product(s) : Dimethyltryptamine
Therapeutic Area : Neurology
Highest Development Status : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable