Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : AU-007,Aldesleukin,Nivolumab
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Aulos Begins Phase 2 AU-007 Combo Trial for Melanoma
Details : AU-007 is a human IgG1 mAb designed to harness the power of interleukin-2 (IL-2) to eradicate solid tumors. It is being evaluated for the treatment of melonoma with nivolumab and aldesleukin.
Product Name : AU-007
Product Type : Antibody
Upfront Cash : Inapplicable
April 14, 2025
Lead Product(s) : AU-007,Aldesleukin,Nivolumab
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : AU-007,Aldesleukin,Avelumab
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Aulos Bio Doses First Patient in Phase 2 Trial of Avelumab and AU-007 in Lung Cancer
Details : AU-007 is a human IgG1 monoclonal antibody designed to harness the power of interleukin-2 (IL-2) to eradicate solid tumors. It is being evaluated for the treatment of non-small cell lung cancer.
Product Name : AU-007
Product Type : Antibody
Upfront Cash : Inapplicable
November 27, 2024
Lead Product(s) : AU-007,Aldesleukin,Avelumab
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : AU-007,Aldesleukin
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Merck Group
Deal Size : Undisclosed
Deal Type : Collaboration
Aulos Bioscience Partners with Merck KGaA to Study Bavencio® with AU-007
Details : Merck KGaA will provide Aulos a free supply of Bavencio to evaluate in combination with AU-007, which is being under clinical investigation for the treatment of solid tumor cancers.
Product Name : AU-007
Product Type : Antibody
Upfront Cash : Undisclosed
May 15, 2024
Lead Product(s) : AU-007,Aldesleukin
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Merck Group
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : AU-007,Aldesleukin
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Aulos Doses First Patient in Phase 2 Trial for IL-2 Antibody for Solid Tumors
Details : AU-007 is an IgG1 monoclonal antibody leveraging IL-2 to eradicate solid tumors, currently in phase 1/2 trials for advanced melanoma and renal cell carcinoma.
Product Name : AU-007
Product Type : Antibody
Upfront Cash : Inapplicable
January 25, 2024
Lead Product(s) : AU-007,Aldesleukin
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : AU-007,Aldesleukin
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : AU-007 is a computationally designed, human IgG1 monoclonal antibody that is highly selective to the CD25-binding portion of IL-2. It is under phase 1/2 clinical development for the treatment of solid tumors.
Product Name : AU-007
Product Type : Antibody
Upfront Cash : Inapplicable
December 18, 2023
Lead Product(s) : AU-007,Aldesleukin
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Aldesleukin
Therapeutic Area : Oncology
Study Phase : Approved FDF
Sponsor : Iovance Biotherapeutics
Deal Size : $206.3 million
Deal Type : Divestment
Clinigen Divests Proleukin® to Iovance Biotherapeutics for £166.7 million
Details : Proleukin® (aldesleukin), a form of interleukin-2, is indicated for the treatment of adults with metastatic melanoma (mM) and metastatic renal cell carcinoma (mRCC).
Product Name : Proleukin
Product Type : Protein
Upfront Cash : $206.3 million
January 23, 2023
Lead Product(s) : Aldesleukin
Therapeutic Area : Oncology
Highest Development Status : Approved FDF
Sponsor : Iovance Biotherapeutics
Deal Size : $206.3 million
Deal Type : Divestment
Lead Product(s) : AU-007,Aldesleukin
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Apple Tree Partners
Deal Size : $60.0 million
Deal Type : Series A Financing
Aulos Bioscience Raises $20 Million in Series A Extension Financing from Apple Tree Partners
Details : The funds will be used to advance Aulos’ lead human monoclonal antibody candidate, AU-007 that is highly selective to the CD25-binding portion of IL-2, through its initial Phase 2 clinical study in solid tumor cancers.
Product Name : AU-007
Product Type : Antibody
Upfront Cash : Undisclosed
January 08, 2023
Lead Product(s) : AU-007,Aldesleukin
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Apple Tree Partners
Deal Size : $60.0 million
Deal Type : Series A Financing
Lead Product(s) : AU-007,Aldesleukin
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : AU-007 is a computationally designed, human IgG1 monoclonal antibody that is highly selective to the CD25-binding portion of IL-2. With a mechanism of action unlike any other IL-2 therapeutic in development, AU-007 leverages IL-2 to reinforce anti-tumor ...
Product Name : AU-007
Product Type : Antibody
Upfront Cash : Inapplicable
January 02, 2023
Lead Product(s) : AU-007,Aldesleukin
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : AU-007,Aldesleukin
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : AU-007 is a computationally designed, human IgG1 monoclonal antibody that is highly selective to the CD25-binding portion of IL-2.AU-007 leverages IL-2 to reinforce anti-tumor immune effects.
Product Name : AU-007
Product Type : Antibody
Upfront Cash : Inapplicable
November 10, 2022
Lead Product(s) : AU-007,Aldesleukin
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Aldesleukin,Riluzole
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Clinigen confirms that Proleukin, interleukin-2 (aldesleukin), supplied for the MIROCALS trial, is currently licensed for metastatic renal cell carcinoma and melanoma in the US and metastatic renal cell carcinoma in certain other countries.
Product Name : Proleukin
Product Type : Protein
Upfront Cash : Inapplicable
August 12, 2022
Lead Product(s) : Aldesleukin,Riluzole
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable