
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : Rilparencel
Therapeutic Area : Nephrology
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
ProKidney Halts One CKD Cell Therapy Phase 3 Trial Considered Surplus to FDA Approval
Details : REACT (rilparencel), an autologous cellular therapy being evaluated to potentially preserve kidney function in diabetic patients.
Product Name : ReACT
Product Type : Miscellaneous
Upfront Cash : Inapplicable
September 03, 2024
Lead Product(s) : Rilparencel
Therapeutic Area : Nephrology
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Rilparencel
Therapeutic Area : Nephrology
Study Phase : Phase III
Sponsor : Jefferies
Deal Size : $140.0 million
Deal Type : Public Offering
ProKidney Closes $140 Million Public Offering of Class A Shares with Underwriters’ Option
Details : REACT (rilparencel), a renal autologous homologous cell admixture, made from expanded autologous SRCs, is currently in a late-stage trial for Diabetic Kidney Disease.
Product Name : ReACT
Product Type : Miscellaneous
Upfront Cash : Undisclosed
June 17, 2024
Lead Product(s) : Rilparencel
Therapeutic Area : Nephrology
Highest Development Status : Phase III
Sponsor : Jefferies
Deal Size : $140.0 million
Deal Type : Public Offering

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Lead Product(s) : Rilparencel
Therapeutic Area : Nephrology
Study Phase : Phase III
Sponsor : Jefferies
Deal Size : Undisclosed
Deal Type : Public Offering
ProKidney Prices Upsized $130 Million Public Offering of Class A Shares
Details : ProKidney will use the proceeds for its drug development, rilparencel (also known as REACT), an autologous cellular therapy evaluated to potentially preserve kidney function in diabetic patients.
Product Name : ReACT
Product Type : Miscellaneous
Upfront Cash : Undisclosed
June 11, 2024
Lead Product(s) : Rilparencel
Therapeutic Area : Nephrology
Highest Development Status : Phase III
Sponsor : Jefferies
Deal Size : Undisclosed
Deal Type : Public Offering

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Lead Product(s) : Rilparencel
Therapeutic Area : Nephrology
Study Phase : Phase III
Sponsor : Jefferies
Deal Size : $125.0 million
Deal Type : Public Offering
ProKidney Proposes $125 Million Public Offering of Class A Ordinary Shares
Details : ProKidney will use the proceeds for its drug development, rilparencel (also known as REACT), an autologous cellular therapy evaluated to potentially preserve kidney function in diabetic patients.
Product Name : ReACT
Product Type : Miscellaneous
Upfront Cash : Undisclosed
June 10, 2024
Lead Product(s) : Rilparencel
Therapeutic Area : Nephrology
Highest Development Status : Phase III
Sponsor : Jefferies
Deal Size : $125.0 million
Deal Type : Public Offering

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Lead Product(s) : Rilparencel
Therapeutic Area : Nephrology
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : REACT, a renal autologous homologous cell admixture, is made from expanded autologous SRCs, obtained from each individual subject’s kidney biopsy. REACT is currently in a Phase 3 development program for Diabetic Kidney Disease.
Product Name : ReACT
Product Type : Miscellaneous
Upfront Cash : Inapplicable
November 13, 2023
Lead Product(s) : Rilparencel
Therapeutic Area : Nephrology
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Renal Autologous Cell Therapy
Therapeutic Area : Nephrology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
A Study of Participants With Chronic Kidney Disease Previously Treated With REACT
Details : Renal Autologous Cell Therapy is a Cell and Gene Therapy drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Diabetic Nephropathies.
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
January 23, 2023
Lead Product(s) : Renal Autologous Cell Therapy
Therapeutic Area : Nephrology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Rilparencel
Therapeutic Area : Nephrology
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : REACT, a renal autologous homologous cell admixture, is made from expanded autologous SRCs, obtained from each individual subject’s kidney biopsy. REACT is currently in a Phase 3 development program for Diabetic Kidney Disease.
Product Name : ReACT
Product Type : Miscellaneous
Upfront Cash : Inapplicable
January 10, 2023
Lead Product(s) : Rilparencel
Therapeutic Area : Nephrology
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Rilparencel
Therapeutic Area : Nephrology
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : REACT® (Renal Autologous Cell Therapy), is a first-of-its-kind, patented, autologous cellular therapy with the potential to not only slow and stabilize the progression of CKD, but in some cases possibly drive meaningful improvement in kidney function.
Product Name : ReACT
Product Type : Miscellaneous
Upfront Cash : Inapplicable
November 03, 2022
Lead Product(s) : Rilparencel
Therapeutic Area : Nephrology
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Rilparencel
Therapeutic Area : Nephrology
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : REACT™ (Renal Autologous Cell Therapy), is a first-of-its-kind, patented, autologous cellular therapy with the potential to not only slow and stabilize the progression of CKD, but in some cases potentially drive meaningful improvement in kidney functio...
Product Name : ReACT
Product Type : Miscellaneous
Upfront Cash : Inapplicable
October 14, 2022
Lead Product(s) : Rilparencel
Therapeutic Area : Nephrology
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Rilparencel
Therapeutic Area : Nephrology
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : REACT is an autologous cell therapy produced from a patient’s own kidney cells that is comprised of a proprietary mixture of progenitor cells that have been selected and cultured so they can be placed back into the patient’s kidney to restore the nat...
Product Name : ReACT
Product Type : Miscellaneous
Upfront Cash : Inapplicable
June 23, 2022
Lead Product(s) : Rilparencel
Therapeutic Area : Nephrology
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
