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Find Clinical Drug Pipeline Developments & Deals by Plus Therapeutics

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                          Top Deals by Deal Size (USD bn)

                          01

                          Peptide Process CMC
                          Not Confirmed
                          Peptide Process CMC
                          Not Confirmed

                          Details : Reyobiq (186-Re Obisbemeda). It is being evaluated for the treatment of leptomeningeal metastases (LM) in patients with lung cancer.

                          Product Name : Reyobiq

                          Product Type : Radiolabeled Compounds

                          Upfront Cash : Inapplicable

                          March 20, 2025

                          Lead Product(s) : 186-Re Obisbemeda

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          Peptide Process CMC
                          Not Confirmed
                          Peptide Process CMC
                          Not Confirmed

                          Details : 186RNL (186-Re Obisbemeda). It is being evaluated for the treatment of leptomeningeal metastases (LM) in patients with lung cancer.

                          Product Name : Undisclosed

                          Product Type : Radiolabeled Compounds

                          Upfront Cash : Inapplicable

                          March 06, 2025

                          Lead Product(s) : 186-Re Obisbemeda

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          Peptide Process CMC
                          Not Confirmed
                          Peptide Process CMC
                          Not Confirmed

                          Details : The net proceeds from the placement will used to advance the clinical development of 186RNL (186-Re Obisbemeda). It is being evaluated for the treatment of Recurrent Glioma.

                          Product Name : Undisclosed

                          Product Type : Radiolabeled Compounds

                          Upfront Cash : Undisclosed

                          March 04, 2025

                          Lead Product(s) : 186-Re Obisbemeda

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : D. Boral Capital

                          Deal Size : $15.0 million

                          Deal Type : Private Placement

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                          04

                          Peptide Process CMC
                          Not Confirmed
                          Peptide Process CMC
                          Not Confirmed

                          Details : The net proceeds from the offering primarily to fund clinical development of its pipeline candidates, including 186RNL (186-Re Obisbemeda) , which is being evaluated for Leptomeningeal Metastases.

                          Product Name : Undisclosed

                          Product Type : Radiolabeled Compounds

                          Upfront Cash : Undisclosed

                          February 18, 2025

                          Lead Product(s) : 186-Re Obisbemeda

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : AIGH Capital Management

                          Deal Size : $3.7 million

                          Deal Type : Private Placement

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                          05

                          Peptide Process CMC
                          Not Confirmed
                          Peptide Process CMC
                          Not Confirmed

                          Details : 186RNL (Rhenium (186Re) obisbemeda) is a novel injectable radiotherapy formulated for direct high-dose radiation delivery in CNS tumors, currently evaluated for leptomeningeal metastases.

                          Product Name : Undisclosed

                          Product Type : Radiolabeled Compounds

                          Upfront Cash : Inapplicable

                          November 03, 2024

                          Lead Product(s) : 186-Re Obisbemeda

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          Peptide Process CMC
                          Not Confirmed
                          Peptide Process CMC
                          Not Confirmed

                          Details : The net proceeds will be used to supports the clinical development of 186RNL (rhenium-186 obisbemeda), a novel injectable radiotherapy, for leptomeningeal metastases.

                          Product Name : Undisclosed

                          Product Type : Radiolabeled Compounds

                          Upfront Cash : Undisclosed

                          July 06, 2024

                          Lead Product(s) : 186-Re Obisbemeda

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : CPRIT

                          Deal Size : $17.6 million

                          Deal Type : Funding

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                          07

                          Peptide Process CMC
                          Not Confirmed
                          Peptide Process CMC
                          Not Confirmed

                          Details : Proceeds will advance the Re-SPECT LM program evaluating 186RNL (rhenium-186 obisbemeda), designed to emit beta energy for tumor destruction.

                          Product Name : Undisclosed

                          Product Type : Radiolabeled Compounds

                          Upfront Cash : $6.5 million

                          June 05, 2024

                          Lead Product(s) : 186-Re Obisbemeda

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : AIGH Capital Management

                          Deal Size : $18.0 million

                          Deal Type : Financing

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                          08

                          Peptide Process CMC
                          Not Confirmed
                          Peptide Process CMC
                          Not Confirmed

                          Details : Proceeds will advance clinical trials for pediatric brain cancer, evaluating 186RNL (rhenium-186 obisbemeda) for tumor tissue destruction.

                          Product Name : Undisclosed

                          Product Type : Radiolabeled Compounds

                          Upfront Cash : Undisclosed

                          April 22, 2024

                          Lead Product(s) : 186-Re Obisbemeda

                          Therapeutic Area : Oncology

                          Highest Development Status : IND Enabling

                          Sponsor : United States Department of Defense

                          Deal Size : $3.0 million

                          Deal Type : Funding

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                          09

                          Peptide Process CMC
                          Not Confirmed
                          Peptide Process CMC
                          Not Confirmed

                          Details : The agreement secures a reliable supply of cGMP Re-186, the radioisotope used in Plus Therapeutics’ lead radiotherapeutic candidate Rhenium (186Re) Obisbemeda, a novel injectable radiotherapy.

                          Product Name : Undisclosed

                          Product Type : Radiolabeled Compounds

                          Upfront Cash : Undisclosed

                          March 12, 2024

                          Lead Product(s) : 186-Re Obisbemeda

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Recipient : IsoTherapeutics Group

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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                          10

                          Peptide Process CMC
                          Not Confirmed
                          Peptide Process CMC
                          Not Confirmed

                          Details : The funding will cover the majority of the development costs of the Company’s lead investigational targeted radiotherapeutic, 186RNL (rhenium-186 obisbemeda), for the treatment of patients with leptomeningeal metastases (LM).

                          Product Name : Undisclosed

                          Product Type : Radiolabeled Compounds

                          Upfront Cash : Undisclosed

                          November 09, 2023

                          Lead Product(s) : 186-Re Obisbemeda

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : CPRIT

                          Deal Size : $17.6 million

                          Deal Type : Funding

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