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    [{"orgOrder":0,"company":"Pierre Fabre","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"FRANCE","productType":"Other Small Molecule","year":"2023","type":"Inapplicable","leadProduct":"Encorafenib","moa":"||BRAF","graph1":"Oncology","graph2":"Approved FDF","graph3":"Pierre Fabre","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral Capsule","sponsorNew":"Pierre Fabre \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"Pierre Fabre \/ Inapplicable"},{"orgOrder":0,"company":"Pierre Fabre","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"FRANCE","productType":"Other Small Molecule","year":"2020","type":"Inapplicable","leadProduct":"Encorafenib","moa":"||BRAF","graph1":"Oncology","graph2":"Approved FDF","graph3":"Pierre Fabre","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral Capsule","sponsorNew":"Pierre Fabre \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"Pierre Fabre \/ Inapplicable"},{"orgOrder":0,"company":"Pierre Fabre","sponsor":"EORTC","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"FRANCE","productType":"Other Small Molecule","year":"2021","type":"Partnership","leadProduct":"Encorafenib","moa":"||BRAF","graph1":"Oncology","graph2":"Phase III","graph3":"Pierre Fabre","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral Capsule","sponsorNew":"Pierre Fabre \/ EORTC","highestDevelopmentStatusID":"10","companyTruncated":"Pierre Fabre \/ EORTC"},{"orgOrder":0,"company":"Pierre Fabre","sponsor":"European Organisation for Research and Treatment of Cancer","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"FRANCE","productType":"Other Small Molecule","year":"2022","type":"Inapplicable","leadProduct":"Encorafenib","moa":"||BRAF","graph1":"Oncology","graph2":"Phase III","graph3":"Pierre Fabre","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral Capsule","sponsorNew":"Pierre Fabre \/ European Organisation for Research and Treatment of Cancer","highestDevelopmentStatusID":"10","companyTruncated":"Pierre Fabre \/ European Organisation for Research and Treatment of Cancer"},{"orgOrder":0,"company":"Pierre Fabre","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"FRANCE","productType":"Other Large Molecule","year":"2024","type":"Inapplicable","leadProduct":"PFL-002","moa":"c-Met receptor","graph1":"Oncology","graph2":"IND Enabling","graph3":"Pierre Fabre","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Pierre Fabre \/ Inapplicable","highestDevelopmentStatusID":"5","companyTruncated":"Pierre Fabre \/ Inapplicable"},{"orgOrder":0,"company":"Pierre Fabre","sponsor":"Scorpion Therapeutics","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"FRANCE","productType":"Other Small Molecule","year":"2024","type":"Inapplicable","leadProduct":"STX-241","moa":"C797S","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Pierre Fabre","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Pierre Fabre \/ Scorpion Therapeutics","highestDevelopmentStatusID":"7","companyTruncated":"Pierre Fabre \/ Scorpion Therapeutics"},{"orgOrder":0,"company":"Pierre Fabre","sponsor":"Ribonexus","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"FRANCE","productType":"Antibody","year":"2021","type":"Licensing Agreement","leadProduct":"K01401","moa":"eIF4A","graph1":"Oncology","graph2":"Preclinical","graph3":"Pierre Fabre","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Pierre Fabre \/ Ribonexus","highestDevelopmentStatusID":"4","companyTruncated":"Pierre Fabre \/ Ribonexus"},{"orgOrder":0,"company":"Pierre Fabre","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"FRANCE","productType":"Other Large Molecule","year":"2024","type":"Inapplicable","leadProduct":"PFL-002","moa":"c-Met receptor","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Pierre Fabre","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Pierre Fabre \/ Inapplicable","highestDevelopmentStatusID":"7","companyTruncated":"Pierre Fabre \/ Inapplicable"},{"orgOrder":0,"company":"Pierre Fabre","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"FRANCE","productType":"Antibody","year":"2020","type":"Inapplicable","leadProduct":"Pembrolizumab","moa":"||VISTA","graph1":"Oncology","graph2":"Phase I","graph3":"Pierre Fabre","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Pierre Fabre \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"Pierre Fabre \/ Inapplicable"},{"orgOrder":0,"company":"Pierre Fabre","sponsor":"Talem Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"FRANCE","productType":"Antibody","year":"2021","type":"Collaboration","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Oncology","graph2":"Discovery","graph3":"Pierre Fabre","amount2":0,"highestDevelopmentShortName":"Discovery","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral","sponsorNew":"Pierre Fabre \/ Talem Therapeutics","highestDevelopmentStatusID":"2","companyTruncated":"Pierre Fabre \/ Talem Therapeutics"}]

    Find Oncology Clinical Drug Pipeline Developments & Deals by Pierre Fabre

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                            01

                            Pierre Fabre

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                            Pierre Fabre

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                            Lead Product(s) : PFL-002

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Pierre Fabre Doses First Patient in NSCLC Phase I/II for MET-Targeting Therapy

                            Details : PFL-002/VERT-002 is a mAb developed by Vertical Bio, acting as a degrader of c-MET, in patients with solid tumors, including non-small cell lung cancer with mutations or amplification of MET.

                            Product Name : VERT-002

                            Product Type : Other Large Molecule

                            Upfront Cash : Inapplicable

                            October 24, 2024

                            Lead Product(s) : PFL-002

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Pierre Fabre

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                            Pierre Fabre

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                            Lead Product(s) : STX-241

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Scorpion Therapeutics

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Pierre Fabre & Scorpion Dose First Patient in PFL-241/STX-241 Lung Cancer Trial

                            Details : PFL-241/STX-241 is an oral therapy designed to selectively inhibit the C797S resistance mutation. It is currently being investigated for the treatment of locally advanced or metastatic NSCLC.

                            Product Name : PFL-241

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            August 10, 2024

                            Lead Product(s) : STX-241

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Scorpion Therapeutics

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Pierre Fabre

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                            Lead Product(s) : PFL-002

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            Pierre Fabre: IND for PFL-002/VERT-002 in Solid Tumors with MET Mutations

                            Details : PFL-002/VERT-002 is a mAb developed by Vertical Bio, acting as a degrader of c-MET, in patients with solid tumors, including non-small cell lung cancer with mutations or amplification of MET.

                            Product Name : VERT-002

                            Product Type : Other Large Molecule

                            Upfront Cash : Inapplicable

                            May 06, 2024

                            Lead Product(s) : PFL-002

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Pierre Fabre

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                            Lead Product(s) : Encorafenib,Binimetinib

                            Therapeutic Area : Oncology

                            Study Phase : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            European Medicines Agency Validates Pierre Fabre Laboratories' Marketing Authorisation Application for Combina...

                            Details : Braftovi (encorafenib) + Mektovi (binimetinib) is approved for the treatment of adult patients with BRAFV600-mutant advanced non-small cell lung cancer (NSCLC), who are either treatment naïve or have received prior therapy.

                            Product Name : Braftovi

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            February 11, 2023

                            Lead Product(s) : Encorafenib,Binimetinib

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Pierre Fabre

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                            Lead Product(s) : Encorafenib,Binimetinib

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : European Organisation for Research and Treatment of Cancer

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Pierre Fabre and EORTC Open a Large Phase III Clinical Study in The Adjuvant Setting of Stage IIB-C Melanoma

                            Details : Braftovi (encorafenib) is an oral small-molecule BRAF kinase inhibitor and binimetinib is an oral small-molecule MEK inhibitor that targets key enzymes in the MAPK signalling pathway (RAS-RAF-MEK-ERK).

                            Product Name : Braftovi

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            May 24, 2022

                            Lead Product(s) : Encorafenib,Binimetinib

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : European Organisation for Research and Treatment of Cancer

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Pierre Fabre

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                            Lead Product(s) : K01401

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : Ribonexus

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Aglaia Therapeutics Becomes Ribonexus and Signs Exclusive License Agreement with Pierre Fabre on Small Molecul...

                            Details : The startup changed its name to Ribonexus, effective since November 2021, to reflect the central role of eIF4A in the translation of specific mRNAs (messenger ribonucleic acids), cancer development and resistance to targeted therapies.

                            Product Name : K01401

                            Product Type : Antibody

                            Upfront Cash : Undisclosed

                            November 18, 2021

                            Lead Product(s) : K01401

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : Ribonexus

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

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                            07

                            Pierre Fabre

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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Oncology

                            Study Phase : Discovery

                            Sponsor : Talem Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Talem Therapeutics Announces Multi-Target Antibody Discovery Research Collaboration with Pierre Fabre

                            Details : Multi-target research collaboration leverages ImmunoPrecise’s powerful antibody discovery technologies with the long-standing expertise of Pierre Fabre in immuno-oncology.

                            Product Name : Undisclosed

                            Product Type : Antibody

                            Upfront Cash : Undisclosed

                            July 10, 2021

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Oncology

                            Highest Development Status : Discovery

                            Sponsor : Talem Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            08

                            Pierre Fabre

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                            Lead Product(s) : Encorafenib,Binimetinib

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : EORTC

                            Deal Size : Undisclosed

                            Deal Type : Partnership

                            DEALS_DEV arrow-down

                            European Organisation for Research and Treatment of Cancer (EORTC) and Pierre Fabre Partner to Address Treatme...

                            Details : The partnership includes the planning, design and execution of a large Phase 3 study of Braftovi (encorafenib) investigating the use of BRAF and MEK targeted therapies to reduce the risk of relapse in this patient population, currently under approval wit...

                            Product Name : Braftovi

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            June 29, 2021

                            Lead Product(s) : Encorafenib,Binimetinib

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : EORTC

                            Deal Size : Undisclosed

                            Deal Type : Partnership

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                            09

                            Pierre Fabre

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                            Lead Product(s) : W0180,Pembrolizumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            Pierre Fabre Initiates a "First in Human" Clinical Trial for An Innovative Monoclonal Antibody (W0180)

                            Details : W0180 is a first-in-class antibody targeting VISTA (V-domain Ig suppressor of T cell Activation). VISTA is a negative checkpoint regulator of T cell response.

                            Product Name : W0180

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            September 11, 2020

                            Lead Product(s) : W0180,Pembrolizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Pierre Fabre

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                            Lead Product(s) : Encorafenib,Cetuximab

                            Therapeutic Area : Oncology

                            Study Phase : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            Pierre Fabre Receives Positive CHMP Opinion for BRAFTOVI® in Combination with Cetuximab for Treatment of BRAF...

                            Details : Phase 3 BEACON CRC trial data showed that BRAFTOVI in combination with cetuximab significantly improved overall survival in patients with BRAFV600E-mutant mCRC and reduced the risk of death by 40%.

                            Product Name : Braftovi

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            January 05, 2020

                            Lead Product(s) : Encorafenib,Cetuximab

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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