Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : mRNA-4157,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Merck & Co
Deal Size : $50.0 million
Deal Type : Private Placement
Personalis Gains Merck Investment and Extends Moderna Collaboration
Details : Merck will leverage Personalis' advanced tumor profiling platform to support the clinical development of V940 (mRNA-4157), which is currently being evaluated for Stage II/IIIB NSCLC.
Product Name : V940
Product Type : Vaccine
Upfront Cash : Undisclosed
December 19, 2024
Lead Product(s) : mRNA-4157,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Merck & Co
Deal Size : $50.0 million
Deal Type : Private Placement
Details : The collaboration aims to examine the efficacy and safety of Opdivo, an immune checkpoint inhibitor, for resectable rectal cancer with dMMR. NCCHE will recruit patients and conduct the trial, Ono will provide nivolumab, and Personalis will perform MRD an...
Product Name : Opdivo
Product Type : Antibody
Upfront Cash : Undisclosed
May 16, 2023
Lead Product(s) : mRNA-4157,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Moderna Therapeutics
Deal Size : Undisclosed
Deal Type : Agreement
Details : Under the terms of the agreement, the companies will Leverage NeXT Platform™ in Personalized mRNA Cancer Vaccine Clinical Trials evaluating mRNA-4157/V940, an investigational personalized cancer vaccine.
Product Name : V940
Product Type : Vaccine
Upfront Cash : Undisclosed
March 02, 2023
Lead Product(s) : mRNA-4157,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Moderna Therapeutics
Deal Size : Undisclosed
Deal Type : Agreement
Lead Product(s) : Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Approved FDF
Sponsor : Olink Proteomics
Deal Size : Undisclosed
Deal Type : Collaboration
Details : The goal of the collaborative study is to characterize key tumor and immunological responses to pembrolizumab (Keytruda) and, in so doing, shine light on the potential mechanisms that lead to either sensitivity or resistance to immunotherapeutics in gast...
Product Name : Keytruda
Product Type : Antibody
Upfront Cash : Undisclosed
April 10, 2022
Lead Product(s) : Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Approved FDF
Sponsor : Olink Proteomics
Deal Size : Undisclosed
Deal Type : Collaboration