[{"orgOrder":0,"company":"Personalis","sponsor":"Ono Pharmaceutical","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Antibody","year":"2023","type":"Collaboration","leadProduct":"Nivolumab","moa":"PD-L1","graph1":"Oncology","graph2":"Phase II","graph3":"Personalis","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Injection","sponsorNew":"Personalis \/ Ono Pharmaceutical","highestDevelopmentStatusID":"8","companyTruncated":"Personalis \/ Ono Pharmaceutical"},{"orgOrder":0,"company":"Personalis","sponsor":"Olink Proteomics","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Antibody","year":"2022","type":"Collaboration","leadProduct":"Pembrolizumab","moa":"PD-1","graph1":"Oncology","graph2":"Approved FDF","graph3":"Personalis","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Personalis \/ Olink Proteomics","highestDevelopmentStatusID":"15","companyTruncated":"Personalis \/ Olink Proteomics"},{"orgOrder":0,"company":"Personalis","sponsor":"Moderna Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Vaccine","year":"2023","type":"Agreement","leadProduct":"mRNA-4157","moa":"||Immunostimulant","graph1":"Oncology","graph2":"Phase II","graph3":"Personalis","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intramuscular Injection","sponsorNew":"Personalis \/ Moderna Therapeutics","highestDevelopmentStatusID":"8","companyTruncated":"Personalis \/ Moderna Therapeutics"},{"orgOrder":0,"company":"Personalis","sponsor":"Merck & Co","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Vaccine","year":"2024","type":"Private Placement","leadProduct":"mRNA-4157","moa":"||Immunostimulant","graph1":"Oncology","graph2":"Phase III","graph3":"Personalis","amount2":0.050000000000000003,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0.050000000000000003,"dosageForm":"Intramuscular Injection","sponsorNew":"Personalis \/ Merck & Co","highestDevelopmentStatusID":"10","companyTruncated":"Personalis \/ Merck & Co"}]

Find Clinical Drug Pipeline Developments & Deals by Personalis

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          AACR Annual meeting
                          Not Confirmed
                          AACR Annual meeting
                          Not Confirmed

                          Details : Merck will leverage Personalis' advanced tumor profiling platform to support the clinical development of V940 (mRNA-4157), which is currently being evaluated for Stage II/IIIB NSCLC.

                          Product Name : V940

                          Product Type : Vaccine

                          Upfront Cash : Undisclosed

                          December 19, 2024

                          Lead Product(s) : mRNA-4157,Pembrolizumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Merck & Co

                          Deal Size : $50.0 million

                          Deal Type : Private Placement

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                          02

                          AACR Annual meeting
                          Not Confirmed
                          AACR Annual meeting
                          Not Confirmed

                          Details : The collaboration aims to examine the efficacy and safety of Opdivo, an immune checkpoint inhibitor, for resectable rectal cancer with dMMR. NCCHE will recruit patients and conduct the trial, Ono will provide nivolumab, and Personalis will perform MRD an...

                          Product Name : Opdivo

                          Product Type : Antibody

                          Upfront Cash : Undisclosed

                          May 16, 2023

                          Lead Product(s) : Nivolumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Ono Pharmaceutical

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          03

                          AACR Annual meeting
                          Not Confirmed
                          AACR Annual meeting
                          Not Confirmed

                          Details : Under the terms of the agreement, the companies will Leverage NeXT Platform™ in Personalized mRNA Cancer Vaccine Clinical Trials evaluating mRNA-4157/V940, an investigational personalized cancer vaccine.

                          Product Name : V940

                          Product Type : Vaccine

                          Upfront Cash : Undisclosed

                          March 02, 2023

                          Lead Product(s) : mRNA-4157,Pembrolizumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Moderna Therapeutics

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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                          04

                          AACR Annual meeting
                          Not Confirmed
                          AACR Annual meeting
                          Not Confirmed

                          Details : The goal of the collaborative study is to characterize key tumor and immunological responses to pembrolizumab (Keytruda) and, in so doing, shine light on the potential mechanisms that lead to either sensitivity or resistance to immunotherapeutics in gast...

                          Product Name : Keytruda

                          Product Type : Antibody

                          Upfront Cash : Undisclosed

                          April 10, 2022

                          Lead Product(s) : Pembrolizumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved FDF

                          Sponsor : Olink Proteomics

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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