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    [{"orgOrder":0,"company":"Eisai","sponsor":"Not Applicable","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not Applicable","newsHeadline":"Eisai Receives Positive Opinion from EMA\u2019S CHMP on Use of Antiepileptic Agent Fycompa\u00ae in Pediatric Patients","therapeuticArea":"Neurology","highestDevelopmentStatus":"Approved","country":"JAPAN","productType":"Small molecule","productStatus":"Approved","date":"September 2020","url1":"","url2":"","graph1":"Neurology","graph2":"Approved"},{"orgOrder":0,"company":"Eisai","sponsor":"Not Applicable","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not Applicable","newsHeadline":"China NMPA Accepts Eisai\u2019s sNDA for Anti-Epileptic Drug Fycompa as Monotherapy for Partial-Onset Seizures, Paediatric Indication for Partial Onset Seizures","therapeuticArea":"Neurology","highestDevelopmentStatus":"Approved","country":"JAPAN","productType":"Small molecule","productStatus":"Approved","date":"October 2020","url1":"","url2":"","graph1":"Neurology","graph2":"Approved"},{"orgOrder":0,"company":"Eisai","sponsor":"Not Applicable","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not Applicable","newsHeadline":"China NMPA Approves Eisai\u2019s Fycompa as Monotherapy for Partial-Onset Seizures in Patients with Epilepsy 4 Years of Age and Older","therapeuticArea":"Neurology","highestDevelopmentStatus":"Approved","country":"JAPAN","productType":"Small molecule","productStatus":"Approved","date":"August 2021","url1":"","url2":"","graph1":"Neurology","graph2":"Approved"},{"orgOrder":0,"company":"Eisai","sponsor":"Catalyst Pharmaceuticals","pharmaFlowCategory":"D","amount":"Undisclosed","upfrontCash":"$160.0 million","newsHeadline":"Catalyst Pharmaceuticals to Acquire U.S. Commercial Rights to FYCOMPA\u00c2\u00ae (Perampanel) CIII From Eisai Co., Ltd","therapeuticArea":"Neurology","highestDevelopmentStatus":"Approved","country":"JAPAN","productType":"Small molecule","productStatus":"Approved","date":"December 2022","url1":"","url2":"","graph1":"Neurology","graph2":"Approved"},{"orgOrder":0,"company":"Eisai","sponsor":"Catalyst Pharmaceuticals","pharmaFlowCategory":"D","amount":"Undisclosed","upfrontCash":"$160.0 million","newsHeadline":"Eisai to Divest Rights for Anti-Epileptic Drug Fycompa\u00ae (perampanel) CIII In United States to Catalyst Pharmaceuticals","therapeuticArea":"Neurology","highestDevelopmentStatus":"Approved","country":"JAPAN","productType":"Small molecule","productStatus":"Approved","date":"December 2022","url1":"","url2":"","graph1":"Neurology","graph2":"Approved"},{"orgOrder":0,"company":"Eisai","sponsor":"Catalyst Pharmaceuticals","pharmaFlowCategory":"D","amount":"Undisclosed","upfrontCash":"$160.0 million","newsHeadline":"Catalyst Pharmaceuticals Completes the Acquisition of U.S. Rights to FYCOMPA\u00ae (Perampanel) CIII","therapeuticArea":"Neurology","highestDevelopmentStatus":"Approved","country":"JAPAN","productType":"Small molecule","productStatus":"Approved","date":"January 2023","url1":"","url2":"","graph1":"Neurology","graph2":"Approved"},{"orgOrder":0,"company":"Eisai","sponsor":"Tsukuba Research Laboratories","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not Applicable","newsHeadline":"Supplementary New Drug Application Submitted in Japan for Antiepileptic Drug Fycompa\u00ae Injection Formulation as A New Route of Administration","therapeuticArea":"Neurology","highestDevelopmentStatus":"Approved","country":"JAPAN","productType":"Small molecule","productStatus":"Approved","date":"August 2022","url1":"","url2":"","graph1":"Neurology","graph2":"Approved"},{"orgOrder":0,"company":"Eisai","sponsor":"Not Applicable","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not Applicable","newsHeadline":"Eisai To Present Latest Data On Fycompa\u00ae (perampanel) Ciii At The 76Th American Epilepsy Society (Aes) Annual Meeting","therapeuticArea":"Neurology","highestDevelopmentStatus":"Approved","country":"JAPAN","productType":"Small molecule","productStatus":"Approved","date":"November 2022","url1":"","url2":"","graph1":"Neurology","graph2":"Approved"},{"orgOrder":0,"company":"Eisai","sponsor":"Not Applicable","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not Applicable","newsHeadline":"Eisai to Present Latest Data on Perampanel at The 76th American Epilepsy Society (AES) Annual Meeting","therapeuticArea":"Neurology","highestDevelopmentStatus":"Approved","country":"JAPAN","productType":"Small molecule","productStatus":"Approved","date":"November 2022","url1":"","url2":"","graph1":"Neurology","graph2":"Approved"},{"orgOrder":0,"company":"Akums Lifesciences","sponsor":"Not Applicable","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not Applicable","newsHeadline":"Akums gets DCGI Approval for Perampanel Oral Suspension","therapeuticArea":"Neurology","highestDevelopmentStatus":"Approved","country":"INDIA","productType":"Small molecule","productStatus":"Approved","date":"June 2023","url1":"","url2":"","graph1":"Neurology","graph2":"Approved"},{"orgOrder":0,"company":"Eisai","sponsor":"Not Applicable","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not Applicable","newsHeadline":"Antiepileptic Drug Fycompa\u00ae Injection Formulation Approved in Japan","therapeuticArea":"Neurology","highestDevelopmentStatus":"Approved","country":"JAPAN","productType":"Small molecule","productStatus":"Approved","date":"January 2024","url1":"","url2":"","graph1":"Neurology","graph2":"Approved"}]

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              Eisai

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              Antiepileptic Drug Fycompa® Injection Formulation Approved in Japan

              Details:

              Fycompa® (perampanel) is a highly selective, non-competitive AMPA glutamate receptor antagonist. It is indicated for the treatment of partial-onset seizures & primary generalized tonic-clonic seizures in patients with epilepsy 12 years of age and older.

              Lead Product(s): Perampanel

              Therapeutic Area: Neurology Product Name: Fycompa

              Highest Development Status: Approved Product Type: Small molecule

              Partner/Sponsor/Collaborator: Not Applicable

              Deal Size: Not Applicable Upfront Cash: Not Applicable

              Deal Type: Not Applicable January 18, 2024

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              Akums Lifesciences

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              Akums gets DCGI Approval for Perampanel Oral Suspension

              Details:

              Perampanel oral suspension is first-in-class anti-epileptic agent, With epileptic seizures being mediated by neurotransmitter glutamate, agent is highly selective, noncompetitive AMPA receptor antagonist that reduces neuronal hyperexcitation associated with seizures.

              Lead Product(s): Perampanel

              Therapeutic Area: Neurology Product Name: Fycompa-Generic

              Highest Development Status: Approved Product Type: Small molecule

              Partner/Sponsor/Collaborator: Not Applicable

              Deal Size: Not Applicable Upfront Cash: Not Applicable

              Deal Type: Not Applicable June 27, 2023

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              Eisai

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              Catalyst Pharmaceuticals Completes the Acquisition of U.S. Rights to FYCOMPA® (Perampanel) CIII

              Details:

              The completion of the acquisition, strengthens the company's Commercial Portfolio with the First and Only AMPA Receptor Antagonist Marketed Product for Epilepsy. Fycompa (perampanel), an oral medication, is a selective non-competitive AMPA receptor antagonist.

              Lead Product(s): Perampanel

              Therapeutic Area: Neurology Product Name: Fycompa

              Highest Development Status: Approved Product Type: Small molecule

              Partner/Sponsor/Collaborator: Catalyst Pharmaceuticals

              Deal Size: Undisclosed Upfront Cash: $160.0 million

              Deal Type: Acquisition January 25, 2023

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              Eisai

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              Eisai to Divest Rights for Anti-Epileptic Drug Fycompa® (perampanel) CIII In United States to Catalyst Pharmaceuticals

              Details:

              Fycompa (perampanel) is a non-competitive AMPA glutamate receptor antagonist used to treat partial-onset seizures with or without secondarily generalized seizures, and as adjunctive treatment of primary generalized tonic-clonic seizures in patients with epilepsy.

              Lead Product(s): Perampanel

              Therapeutic Area: Neurology Product Name: Fycompa

              Highest Development Status: Approved Product Type: Small molecule

              Partner/Sponsor/Collaborator: Catalyst Pharmaceuticals

              Deal Size: Undisclosed Upfront Cash: $160.0 million

              Deal Type: Divestment December 20, 2022

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              Eisai

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              Catalyst Pharmaceuticals to Acquire U.S. Commercial Rights to FYCOMPA® (Perampanel) CIII From Eisai Co., Ltd

              Details:

              Fycompa (perampanel), an oral medication, is a selective non-competitive AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) receptor antagonist.

              Lead Product(s): Perampanel

              Therapeutic Area: Neurology Product Name: Fycompa

              Highest Development Status: Approved Product Type: Small molecule

              Partner/Sponsor/Collaborator: Catalyst Pharmaceuticals

              Deal Size: Undisclosed Upfront Cash: $160.0 million

              Deal Type: Acquisition December 19, 2022

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              Eisai

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              Eisai To Present Latest Data On Fycompa® (perampanel) Ciii At The 76Th American Epilepsy Society (Aes) Annual Meeting

              Details:

              Perampanel (Fycompa) is first-in-class AED with epileptic seizures being mediated by neurotransmitter glutamate, agent is highly selective, noncompetitive AMPA receptor antagonist reduces neuronal hyperexcitation.

              Lead Product(s): Perampanel

              Therapeutic Area: Neurology Product Name: Fycompa

              Highest Development Status: Approved Product Type: Small molecule

              Partner/Sponsor/Collaborator: Not Applicable

              Deal Size: Not Applicable Upfront Cash: Not Applicable

              Deal Type: Not Applicable November 24, 2022

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              Eisai

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              Eisai to Present Latest Data on Perampanel at The 76th American Epilepsy Society (AES) Annual Meeting

              Details:

              Perampanel is first-in-class anti-epileptic agent, With epileptic seizures being mediated by neurotransmitter glutamate, agent is highly selective, noncompetitive AMPA receptor antagonist that reduces neuronal hyperexcitation associated with seizures.

              Lead Product(s): Perampanel

              Therapeutic Area: Neurology Product Name: Fycompa

              Highest Development Status: Approved Product Type: Small molecule

              Partner/Sponsor/Collaborator: Not Applicable

              Deal Size: Not Applicable Upfront Cash: Not Applicable

              Deal Type: Not Applicable November 24, 2022

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              Eisai

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              Supplementary New Drug Application Submitted in Japan for Antiepileptic Drug Fycompa® Injection Formulation as A New Route of Administration

              Details:

              Fycompa is a first-in-class AED discovered at Eisai’s Tsukuba Research Laboratories. The agent is a highly selective, noncompetitive AMPA receptor antagonist that is postulated to reduce neuronal hyper-excitation associated with seizures.

              Lead Product(s): Perampanel

              Therapeutic Area: Neurology Product Name: Fycompa

              Highest Development Status: Approved Product Type: Small molecule

              Partner/Sponsor/Collaborator: Tsukuba Research Laboratories

              Deal Size: Not Applicable Upfront Cash: Not Applicable

              Deal Type: Not Applicable August 31, 2022

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              Eisai

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              China NMPA Approves Eisai’s Fycompa as Monotherapy for Partial-Onset Seizures in Patients with Epilepsy 4 Years of Age and Older

              Details:

              Fycompa has already been approved in China as an adjunctive treatment for partial-onset seizures with or without secondarily generalized seizures in patients with epilepsy 12 years of age and older.

              Lead Product(s): Perampanel

              Therapeutic Area: Neurology Product Name: Fycompa

              Highest Development Status: Approved Product Type: Small molecule

              Partner/Sponsor/Collaborator: Not Applicable

              Deal Size: Not Applicable Upfront Cash: Not Applicable

              Deal Type: Not Applicable August 03, 2021

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              Eisai

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              China NMPA Accepts Eisai’s sNDA for Anti-Epileptic Drug Fycompa as Monotherapy for Partial-Onset Seizures, Paediatric Indication for Partial Onset Seizures

              Details:

              The submission covering partial-onset seizures in pediatric patients was based on the results of a Phase III study of Fycompa as an adjunctive therapy conducted globally on pediatric patients with uncontrolled partial onset seizures/primary generalized tonic-clonic seizures.

              Lead Product(s): Perampanel

              Therapeutic Area: Neurology Product Name: Fycompa

              Highest Development Status: Approved Product Type: Small molecule

              Partner/Sponsor/Collaborator: Not Applicable

              Deal Size: Not Applicable Upfront Cash: Not Applicable

              Deal Type: Not Applicable October 16, 2020

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