Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : FXR314
Therapeutic Area : Gastroenterology
Study Phase : Phase I
Sponsor : Eli Lilly
Deal Size : $60.0 million
Deal Type : Acquisition
Lilly Pays $10M Upfront for Organovo’s FXR Agonist Program
Details : Through the acquisition, Lilly will leverage FXR program of Organovo, which includes FXR314, it is being evaluated for the treatment of Inflammatory Bowel Disease.
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : $10.0 million
February 25, 2025
Lead Product(s) : FXR314
Therapeutic Area : Gastroenterology
Highest Development Status : Phase I
Sponsor : Eli Lilly
Deal Size : $60.0 million
Deal Type : Acquisition
Lead Product(s) : KIVU-107
Therapeutic Area : Oncology
Study Phase : IND Enabling
Recipient : Kivu Bioscience
Deal Size : $92.0 million
Deal Type : Series A Financing
Kivu Bioscience Raises $92M to Advance Antibody-Drug Conjugates
Details : The financing will aims to support the clinical development of multiple antibody-drug conjugate (ADC) programs, which include KIVU-107. It is being evaluated for the treatment of neoplasms.
Product Name : Undisclosed
Product Type : Other Large Molecule
Upfront Cash : Undisclosed
October 28, 2024
Lead Product(s) : KIVU-107
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Recipient : Kivu Bioscience
Deal Size : $92.0 million
Deal Type : Series A Financing
Lead Product(s) : AVC-101,Cyclophosphamide,Fludarabine Phosphate
Therapeutic Area : Oncology
Study Phase : Phase I
Recipient : AvenCell Therapeutics
Deal Size : $112.0 million
Deal Type : Series B Financing
AvenCell Raises $112 Million in Series B; Funding Led by Novo Holdings
Details : The proceeds will accelerate AvenCell's proprietary Universal Switchable CAR-T cell therapy platform, including AVC-101, for a wide range of hematologic malignancies and auto-immune diseases.
Product Name : Undisclosed
Product Type : Cell and Gene therapy
Upfront Cash : Undisclosed
October 22, 2024
Lead Product(s) : AVC-101,Cyclophosphamide,Fludarabine Phosphate
Therapeutic Area : Oncology
Highest Development Status : Phase I
Recipient : AvenCell Therapeutics
Deal Size : $112.0 million
Deal Type : Series B Financing
Lead Product(s) : FXR314
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Jonestrading Institutional Services
Deal Size : $5.2 million
Deal Type : Public Offering
Organovo Holdings, Inc. Announces Pricing of $5.25 Million Public Offering
Details : Proceeds will advance the company's pipeline, including lead molecule FXR314, targeting inflammatory bowel disease and applications in metabolic liver disease.
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
August 05, 2024
Lead Product(s) : FXR314
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Jonestrading Institutional Services
Deal Size : $5.2 million
Deal Type : Public Offering
Lead Product(s) : MYX2468
Therapeutic Area : Oncology
Study Phase : Preclinical
Recipient : Myricx Bio
Deal Size : $114.0 million
Deal Type : Series A Financing
Novo Holdings Leads £90M Financing for Myricx Bio ADC Payload Class
Details : The financing aims to fund the advancement of Myricx's proprietary pipeline of N-Myristoyltransferase inhibitor MYX2468 for the treatment of neoplasms.
Product Name : Undisclosed
Product Type : Other Large Molecule
Upfront Cash : Undisclosed
July 07, 2024
Lead Product(s) : MYX2468
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Recipient : Myricx Bio
Deal Size : $114.0 million
Deal Type : Series A Financing
Lead Product(s) : FXR314
Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Organovo Reveals Positive Phase 2 Results for FXR314 in MASH
Details : The company’s lead molecule, FXR314, the non-steroidal, non-bile acid FXR agonist, is being developed for the treatment of metabolic function-associated steatohepatitis (MASH).
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
April 15, 2024
Lead Product(s) : FXR314
Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : CUSP06
Therapeutic Area : Oncology
Study Phase : IND Enabling
Recipient : OnCusp Therapeutics
Deal Size : $100.0 million
Deal Type : Series A Financing
OnCusp Raises $100 Million in Oversubscribed Series A Financing for Cancer Assets
Details : The proceeds will be used to advance CUSP06, the company's antibody drug conjugate (ADC) targeting CDH6 against cancer, toward clinical proof-of-concept.
Product Name : Undisclosed
Product Type : Antibody-drug Conjugate
Upfront Cash : Undisclosed
April 01, 2024
Lead Product(s) : CUSP06
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Recipient : OnCusp Therapeutics
Deal Size : $100.0 million
Deal Type : Series A Financing
Lead Product(s) : Oremepermin Alpha
Therapeutic Area : Ophthalmology
Study Phase : Phase I/ Phase II
Recipient : Claris Bio
Deal Size : $57.0 million
Deal Type : Series A Financing
Claris Bio Prepares for Next Stage with New Investor and Late-Stage Data in 2024
Details : The net proceeds will be used to advance CSB-001 (oremepermin alfa), a topical ocular biologic solution of dHGF, targets complete healing of the cornea surface in eyes with Neurotrophic Keratopathy.
Product Name : Undisclosed
Product Type : Other Large Molecule
Upfront Cash : Undisclosed
April 01, 2024
Lead Product(s) : Oremepermin Alpha
Therapeutic Area : Ophthalmology
Highest Development Status : Phase I/ Phase II
Recipient : Claris Bio
Deal Size : $57.0 million
Deal Type : Series A Financing
Lead Product(s) : NMD670
Therapeutic Area : Genetic Disease
Study Phase : Phase II
Recipient : NMD PHARMA
Deal Size : $80.0 million
Deal Type : Series B Financing
NMD Pharma Raises €75 Million (~$80 million) in a Series B Financing
Details : The proceeds will be used to complete three Phase 2 clinical studies of first-in-class ClC-1 molecule inhibitor NMD670 in myasthenia gravis, spinal muscular atrophy and Charcot-Marie-Tooth disease.
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
November 15, 2023
Lead Product(s) : NMD670
Therapeutic Area : Genetic Disease
Highest Development Status : Phase II
Recipient : NMD PHARMA
Deal Size : $80.0 million
Deal Type : Series B Financing
Lead Product(s) : ML-007C-MA
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase I
Recipient : MapLight Therapeutics
Deal Size : $225.0 million
Deal Type : Series C Financing
Details : The net funding will advance ML-007C-MA, a novel M1/M4 muscarinic agonist agent combined with a precision matched peripheral muscarinic antagonist, into Phase 2 trials for schizophrenia and Alzheimer's disease psychosis in 2024.
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
October 31, 2023
Lead Product(s) : ML-007C-MA
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase I
Recipient : MapLight Therapeutics
Deal Size : $225.0 million
Deal Type : Series C Financing