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                            Top Deals by Deal Size (USD bn)

                            01

                            F. Hoffmann-La Roche

                            Switzerland arrow
                            OTS 2025
                            Not Confirmed

                            F. Hoffmann-La Roche

                            Switzerland arrow
                            OTS 2025
                            Not Confirmed
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                            • EDQM
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                            Lead Product(s) : Inavolisib

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Inavolisib Treatments in Early-Stage PIK3CA-Mutated Breast Cancer

                            Details : Inavolisib is a Other Small Molecule drug candidate, which is currently being evaluated in Phase II clinical studies for the treatment of Breast Neoplasms.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            July 08, 2025

                            Lead Product(s) : Inavolisib

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Novartis Pharmaceuticals Corporation

                            Switzerland arrow
                            OTS 2025
                            Not Confirmed

                            Novartis Pharmaceuticals Corporation

                            Switzerland arrow
                            OTS 2025
                            Not Confirmed
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                            • EDQM
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                            Lead Product(s) : Luxdegalutamide

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            JSB462 + 177Lu Vipivotide Safety and Efficacy In mCRPC

                            Details : JSB462 (Luxdegalutamide) is a PROTACs drug candidate, which is currently being evaluated in Phase II clinical studies for the treatment of Prostatic Neoplasms, Castration-Resistant.

                            Product Name : JSB462

                            Product Type : PROTACs

                            Upfront Cash : Inapplicable

                            July 02, 2025

                            Lead Product(s) : Luxdegalutamide

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Novartis Pharmaceuticals Corporation

                            Switzerland arrow
                            OTS 2025
                            Not Confirmed

                            Novartis Pharmaceuticals Corporation

                            Switzerland arrow
                            OTS 2025
                            Not Confirmed
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                            Lead Product(s) : Luxdegalutamide

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            JSB462 + Abiraterone Safety and Efficacy In mHSPC Adults

                            Details : JSB462 (Luxdegalutamide) is a PROTACs drug candidate, which is currently being evaluated in Phase II clinical studies for the treatment of Prostatic Neoplasms.

                            Product Name : JSB462

                            Product Type : PROTACs

                            Upfront Cash : Inapplicable

                            May 28, 2025

                            Lead Product(s) : Luxdegalutamide

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Ionctura

                            Switzerland arrow
                            OTS 2025
                            Not Confirmed

                            Ionctura

                            Switzerland arrow
                            OTS 2025
                            Not Confirmed
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                            Lead Product(s) : Roginolisib

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            iOnctura Commences Randomized Phase II Study in Metastatic Uveal Melanoma

                            Details : IOA-244 (roginolisib) is an orally dosed small molecule allosteric modulator of PI3Kδ. It is being evaluated for the treatment of metastatic uveal melanoma.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            March 20, 2025

                            Lead Product(s) : Roginolisib

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Debiopharm

                            Switzerland arrow
                            OTS 2025
                            Not Confirmed

                            Debiopharm

                            Switzerland arrow
                            OTS 2025
                            Not Confirmed
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                            Lead Product(s) : Debio 0123,Sacituzumab Govitecan

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : MEDSIR

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            MEDSIR & Debiopharm Begin WIN-B Trial in Breast Cancer

                            Details : Debio 0123 is an oral, potent, highly selective, and brain-penetrant WEE1 inhibitor is being evaluated with trodelvy for HR-positive/HER2-negative triple negative breast neoplasms.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            February 25, 2025

                            Lead Product(s) : Debio 0123,Sacituzumab Govitecan

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : MEDSIR

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Ionctura

                            Switzerland arrow
                            OTS 2025
                            Not Confirmed

                            Ionctura

                            Switzerland arrow
                            OTS 2025
                            Not Confirmed
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                            Lead Product(s) : Roginolisib

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Randomised Phase II Study of Roginolisib in Patients With Advanced/Metastatic Uveal Melanoma

                            Details : Roginolisib is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Uveal Melanoma.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            December 04, 2024

                            Lead Product(s) : Roginolisib

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Novartis Pharmaceuticals Corporation

                            Switzerland arrow
                            OTS 2025
                            Not Confirmed

                            Novartis Pharmaceuticals Corporation

                            Switzerland arrow
                            OTS 2025
                            Not Confirmed
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                            Lead Product(s) : Asciminib

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Open-label Study of Asciminib for CML-CP or CML-AP Patients With T315I Mutation Who Are Resistant, Intolerant ...

                            Details : Asciminib is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Leukemia, Myelogenous, Chronic, BCR-ABL Positive.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            July 23, 2024

                            Lead Product(s) : Asciminib

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            ADC Therapeutics

                            Switzerland arrow
                            OTS 2025
                            Not Confirmed

                            ADC Therapeutics

                            Switzerland arrow
                            OTS 2025
                            Not Confirmed
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                            Lead Product(s) : Loncastuximab Tesirine

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            ADC Therapeutics Announces Initial Data from Phase 2 of Zynlonta

                            Details : Zynlonta (loncastuximab tesirine), an antibody-drug conjugate (ADC) targeting CD19, is is being investigated for the treatment of adult patients with relapsed/refractory (r/r) marginal zone lymphoma.

                            Product Name : Zynlonta

                            Product Type : Antibody-drug Conjugate

                            Upfront Cash : Inapplicable

                            May 06, 2024

                            Lead Product(s) : Loncastuximab Tesirine

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Eisai Inc

                            U.S.A arrow
                            OTS 2025
                            Not Confirmed

                            Eisai Inc

                            U.S.A arrow
                            OTS 2025
                            Not Confirmed
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                            Lead Product(s) : BB-1701

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Bliss Bio

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Study of BB-1701 in Previously Treated Participants With Human Epidermal Growth Factor Receptor 2 (HER2)-Pos...

                            Details : BB-1701 is a Antibody-drug Conjugate drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Breast Neoplasms.

                            Product Name : Undisclosed

                            Product Type : Antibody-drug Conjugate

                            Upfront Cash : Inapplicable

                            January 03, 2024

                            Lead Product(s) : BB-1701

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Bliss Bio

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Rhizen Pharmaceuticals

                            Switzerland arrow
                            OTS 2025
                            Not Confirmed

                            Rhizen Pharmaceuticals

                            Switzerland arrow
                            OTS 2025
                            Not Confirmed
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                            Lead Product(s) : Tenalisib

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Incozen Therapeutics

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Efficacy and Safety of Tenalisib in Patients With Metastatic Triple Negative Breast Cancer (TNBC)

                            Details : Tenalisib is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Triple Negative Breast Neoplasms.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            January 03, 2024

                            Lead Product(s) : Tenalisib

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Incozen Therapeutics

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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