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Bio"},{"orgOrder":0,"company":"Medigene","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"GERMANY","productType":"Undisclosed","year":"2023","type":"Inapplicable","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Oncology","graph2":"Phase I","graph3":"Medigene","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Medigene \/ Undisclosed","highestDevelopmentStatusID":"6","companyTruncated":"Medigene \/ Undisclosed"},{"orgOrder":0,"company":"Medigene","sponsor":"BioNTech","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"GERMANY","productType":"Undisclosed","year":"2022","type":"Collaboration","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Oncology","graph2":"Phase I","graph3":"Medigene","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Medigene \/ BioNTech","highestDevelopmentStatusID":"6","companyTruncated":"Medigene \/ BioNTech"},{"orgOrder":0,"company":"Medigene","sponsor":"EpimAb Biotherapeutics","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"GERMANY","productType":"Undisclosed","year":"2025","type":"Partnership","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Oncology","graph2":"Phase I","graph3":"Medigene","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Medigene \/ EpimAb Biotherapeutics","highestDevelopmentStatusID":"6","companyTruncated":"Medigene \/ EpimAb Biotherapeutics"},{"orgOrder":0,"company":"Medigene","sponsor":"BioNTech","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"GERMANY","productType":"Undisclosed","year":"2024","type":"Collaboration","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Oncology","graph2":"Phase I","graph3":"Medigene","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Medigene \/ BioNTech","highestDevelopmentStatusID":"6","companyTruncated":"Medigene \/ BioNTech"},{"orgOrder":0,"company":"Tubulis","sponsor":"Bristol Myers Squibb","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"GERMANY","productType":"Undisclosed","year":"2023","type":"Licensing Agreement","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Oncology","graph2":"Phase I","graph3":"Tubulis","amount2":1.02,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":1.02,"dosageForm":"Undisclosed","sponsorNew":"Tubulis \/ Bristol Myers Squibb","highestDevelopmentStatusID":"6","companyTruncated":"Tubulis \/ Bristol Myers Squibb"},{"orgOrder":0,"company":"Boehringer Ingelheim GmbH","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"GERMANY","productType":"Microorganism","year":"2025","type":"Inapplicable","leadProduct":"BI1831169","moa":"Tumor cell lysis","graph1":"Oncology","graph2":"Phase I","graph3":"Boehringer Ingelheim GmbH","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Boehringer Ingelheim GmbH \/ Undisclosed","highestDevelopmentStatusID":"6","companyTruncated":"Boehringer Ingelheim GmbH \/ Undisclosed"},{"orgOrder":0,"company":"Miltenyi Biotec","sponsor":"Iovance Biotherapeutics | UPMC Hillman Cancer Center","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"GERMANY","productType":"Cell & Gene Therapy","year":"2025","type":"Inapplicable","leadProduct":"Autologous Pleural Infiltrating T-Cell","moa":"Undisclosed","graph1":"Oncology","graph2":"Phase I","graph3":"Miltenyi Biotec","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Catheter","sponsorNew":"Miltenyi Biotec \/ Iovance Biotherapeutics | UPMC Hillman Cancer Center","highestDevelopmentStatusID":"6","companyTruncated":"Miltenyi Biotec \/ Iovance Biotherapeutics | UPMC Hillman Cancer Center"},{"orgOrder":0,"company":"Miltenyi Biotec","sponsor":"Verismo Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"GERMANY","productType":"Cell & Gene Therapy","year":"2025","type":"Collaboration","leadProduct":"SynKIR-110","moa":"MSLN","graph1":"Oncology","graph2":"Phase I","graph3":"Miltenyi Biotec","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Miltenyi Biotec \/ Verismo Therapeutics","highestDevelopmentStatusID":"6","companyTruncated":"Miltenyi Biotec \/ Verismo Therapeutics"},{"orgOrder":0,"company":"Bayer AG","sponsor":"Dorothy Sipkins","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"GERMANY","productType":"Miscellaneous","year":"2021","type":"Inapplicable","leadProduct":"Copanlisib","moa":"PI3-kinase p110-delta subunit | PI3-kinase p110-alpha subunit","graph1":"Oncology","graph2":"Phase I","graph3":"Bayer AG","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Bayer AG \/ Dorothy Sipkins","highestDevelopmentStatusID":"6","companyTruncated":"Bayer AG \/ Dorothy Sipkins"},{"orgOrder":0,"company":"Boehringer Ingelheim GmbH","sponsor":"Aktion Bronchialkarzinom","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"GERMANY","productType":"Miscellaneous","year":"2012","type":"Inapplicable","leadProduct":"Nintedanib Esylate","moa":"Platelet-derived growth factor receptor | Fibroblast growth factor receptor | Vascular endothelial growth factor receptor","graph1":"Oncology","graph2":"Phase I","graph3":"Boehringer Ingelheim GmbH","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Capsule","sponsorNew":"Boehringer Ingelheim GmbH \/ Aktion Bronchialkarzinom","highestDevelopmentStatusID":"6","companyTruncated":"Boehringer Ingelheim GmbH \/ Aktion Bronchialkarzinom"},{"orgOrder":0,"company":"Boehringer Ingelheim GmbH","sponsor":"Aktion Bronchialkarzinom","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"GERMANY","productType":"Miscellaneous","year":"2012","type":"Inapplicable","leadProduct":"Nintedanib Esylate","moa":"Platelet-derived growth factor receptor | Fibroblast growth factor receptor | Vascular endothelial growth factor receptor","graph1":"Oncology","graph2":"Phase I","graph3":"Boehringer Ingelheim GmbH","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Capsule","sponsorNew":"Boehringer Ingelheim GmbH \/ Aktion Bronchialkarzinom","highestDevelopmentStatusID":"6","companyTruncated":"Boehringer Ingelheim GmbH \/ Aktion Bronchialkarzinom"},{"orgOrder":0,"company":"Bayer AG","sponsor":"Zhonglin Hao","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"GERMANY","productType":"Antibody, Unconjugated","year":"2021","type":"Inapplicable","leadProduct":"Durvalumab","moa":"Programmed cell death 1 ligand 1","graph1":"Oncology","graph2":"Phase I","graph3":"Bayer AG","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Bayer AG \/ Zhonglin Hao","highestDevelopmentStatusID":"6","companyTruncated":"Bayer AG \/ Zhonglin Hao"},{"orgOrder":0,"company":"Boehringer Ingelheim GmbH","sponsor":"Santosh Kesari","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"GERMANY","productType":"Miscellaneous","year":"2015","type":"Inapplicable","leadProduct":"Afatinib","moa":"Receptor protein-tyrosine kinase erbB-2","graph1":"Oncology","graph2":"Phase I","graph3":"Boehringer Ingelheim GmbH","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Boehringer Ingelheim GmbH \/ Santosh Kesari","highestDevelopmentStatusID":"6","companyTruncated":"Boehringer Ingelheim GmbH \/ Santosh Kesari"},{"orgOrder":0,"company":"Bayer AG","sponsor":"Gustave Roussy","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"GERMANY","productType":"Miscellaneous","year":"2023","type":"Inapplicable","leadProduct":"Regorafenib","moa":"Serine\/threonine-protein kinase B-raf | Nerve growth factor receptor Trk-A | Tyrosine-protein kinase FRK | Fibroblast growth factor receptor 2 | MAP kinase p38 beta | Tyrosine-protein kinase ABL | Stem cell growth factor receptor | Vascular endothelial growth factor receptor | Fibroblast growth factor receptor 1 | Serine\/threonine-protein kinase RAF | Platelet-derived growth factor receptor | Tyrosine-protein kinase receptor RET | Discoidin domain-containing receptor 2 | Ephrin type-A receptor 2 | Tyrosine-protein kinase TIE-2","graph1":"Oncology","graph2":"Phase I","graph3":"Bayer AG","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Bayer AG \/ Gustave Roussy","highestDevelopmentStatusID":"6","companyTruncated":"Bayer AG \/ Gustave Roussy"},{"orgOrder":0,"company":"Boehringer Ingelheim GmbH","sponsor":"Anne Beaven","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"GERMANY","productType":"Miscellaneous","year":"2016","type":"Inapplicable","leadProduct":"Volasertib","moa":"Serine\/threonine-protein kinase PLK1","graph1":"Oncology","graph2":"Phase I","graph3":"Boehringer Ingelheim GmbH","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Boehringer Ingelheim GmbH \/ Anne Beaven","highestDevelopmentStatusID":"6","companyTruncated":"Boehringer Ingelheim GmbH \/ Anne Beaven"},{"orgOrder":0,"company":"Bayer AG","sponsor":"Anders Ull\u00e9n","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"GERMANY","productType":"Miscellaneous","year":"2013","type":"Inapplicable","leadProduct":"Vinflunine","moa":"Tubulin","graph1":"Oncology","graph2":"Phase I","graph3":"Bayer AG","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Bayer AG \/ Anders Ull\u00e9n","highestDevelopmentStatusID":"6","companyTruncated":"Bayer AG \/ Anders Ull\u00e9n"},{"orgOrder":0,"company":"Abalos Therapeutics","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"GERMANY","productType":"Microorganism","year":"2025","type":"Inapplicable","leadProduct":"ABX-001","moa":"Undisclosed","graph1":"Oncology","graph2":"Phase I","graph3":"Abalos Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Abalos Therapeutics \/ Undisclosed","highestDevelopmentStatusID":"6","companyTruncated":"Abalos Therapeutics \/ Undisclosed"},{"orgOrder":0,"company":"Boehringer Ingelheim GmbH","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"GERMANY","productType":"Miscellaneous","year":"2025","type":"Inapplicable","leadProduct":"BI 3810944","moa":"Undisclosed","graph1":"Oncology","graph2":"Phase I","graph3":"Boehringer Ingelheim GmbH","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Boehringer Ingelheim GmbH \/ Undisclosed","highestDevelopmentStatusID":"6","companyTruncated":"Boehringer Ingelheim GmbH \/ Undisclosed"},{"orgOrder":0,"company":"Abalos Therapeutics","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"GERMANY","productType":"Microorganism","year":"2025","type":"Inapplicable","leadProduct":"ABX-001","moa":"Undisclosed","graph1":"Oncology","graph2":"Phase I","graph3":"Abalos Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Abalos Therapeutics \/ Undisclosed","highestDevelopmentStatusID":"6","companyTruncated":"Abalos Therapeutics \/ Undisclosed"},{"orgOrder":0,"company":"CureVac","sponsor":"BioNTech","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"GERMANY","productType":"Vaccine","year":"2025","type":"Acquisition","leadProduct":"CV09050101","moa":"SARS-CoV-2 S","graph1":"Oncology","graph2":"Phase I","graph3":"CureVac","amount2":1.25,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":1.25,"dosageForm":"Injection","sponsorNew":"CureVac \/ BioNTech","highestDevelopmentStatusID":"6","companyTruncated":"CureVac \/ BioNTech"},{"orgOrder":0,"company":"Boehringer Ingelheim GmbH","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"GERMANY","productType":"Undisclosed","year":"2025","type":"Inapplicable","leadProduct":"BI 3820768","moa":"Undisclosed","graph1":"Oncology","graph2":"Phase I","graph3":"Boehringer Ingelheim GmbH","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Boehringer Ingelheim GmbH \/ Undisclosed","highestDevelopmentStatusID":"6","companyTruncated":"Boehringer Ingelheim GmbH \/ Undisclosed"},{"orgOrder":0,"company":"Merck Group","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"GERMANY","productType":"Antibody-drug Conjugate","year":"2025","type":"Inapplicable","leadProduct":"M7437","moa":"Ly6E","graph1":"Oncology","graph2":"Phase I","graph3":"Merck Group","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Merck Group \/ Undisclosed","highestDevelopmentStatusID":"6","companyTruncated":"Merck Group \/ Undisclosed"}]

Find Oncology Drugs in Phase I Clinical Development in GERMANY

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                          Top Deals by Deal Size (USD bn)

                          01

                          Details : Treosulfan is a Cytotoxic Drug drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Leukemia, Myeloid, Acute.

                          Product Name : Undisclosed

                          Product Type : Cytotoxic Drug

                          Upfront Cash : Inapplicable

                          September 09, 2022

                          Lead Product(s) : Treosulfan,Fludarabine Phosphate

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Syneos Health

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Company Banner

                          02

                          Lead Product(s) : XB002,Nivolumab

                          Therapeutic Area : Oncology

                          Study Phase : Phase I

                          Sponsor : Exelixis

                          Deal Size : Undisclosed

                          Deal Type : Agreement

                          Details : Through the agreement, Novosep will perform the process development of the XB002 ADC. which is being evaluated in the early-stage clinical trial studies for the treatment of non-small cell lung cancer and cervical cancer.

                          Product Name : Undisclosed

                          Product Type : Antibody-drug Conjugate

                          Upfront Cash : Undisclosed

                          July 06, 2021

                          Lead Product(s) : XB002,Nivolumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Exelixis

                          Deal Size : Undisclosed

                          Deal Type : Agreement

                          Axplora CB

                          03

                          VMX
                          Not Confirmed
                          VMX
                          Not Confirmed

                          Details : M7437 is a antibody-drug conjugate, which is currently being evaluated in Phase I clinical studies for the treatment of Neoplasms.

                          Product Name : Undisclosed

                          Product Type : Antibody-drug Conjugate

                          Upfront Cash : Inapplicable

                          December 31, 2025

                          Lead Product(s) : M7437

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          VMX
                          Not Confirmed
                          VMX
                          Not Confirmed

                          Details : BI 3820768 is currently being evaluated in Phase I clinical studies for the treatment of Neoplasms.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Inapplicable

                          December 29, 2025

                          Lead Product(s) : BI 3820768

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          VMX
                          Not Confirmed
                          VMX
                          Not Confirmed

                          Details : Through the acquisition of CV09050101, a vaccine targeting SARS-CoV-2 S, the deal aims to advance research in glioblastoma.

                          Product Name : Undisclosed

                          Product Type : Vaccine

                          Upfront Cash : Undisclosed

                          December 18, 2025

                          Lead Product(s) : CV09050101

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : BioNTech

                          Deal Size : $1,250.0 million

                          Deal Type : Acquisition

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                          06

                          VMX
                          Not Confirmed
                          VMX
                          Not Confirmed

                          Details : ABX-001 is a Microorganism drug candidate, which is currently being evaluated in Phase I clinical studies for the treatment of Neoplasms.

                          Product Name : Undisclosed

                          Product Type : Microorganism

                          Upfront Cash : Inapplicable

                          November 17, 2025

                          Lead Product(s) : ABX-001,Pembrolizumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          VMX
                          Not Confirmed
                          VMX
                          Not Confirmed

                          Details : BI 3810944 is a small molecule drug candidate, which is currently being evaluated in Phase I clinical studies for the treatment of Neoplasms.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          November 04, 2025

                          Lead Product(s) : BI 3810944

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          VMX
                          Not Confirmed
                          VMX
                          Not Confirmed

                          Details : ABX-001, a microorganism-based therapy, shows promise in treating refractory/relapsed solid tumors.

                          Product Name : ABX-001

                          Product Type : Microorganism

                          Upfront Cash : Inapplicable

                          October 23, 2025

                          Lead Product(s) : ABX-001,Pembrolizumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          VMX
                          Not Confirmed
                          VMX
                          Not Confirmed

                          Lead Product(s) : Autologous Pleural Infiltrating T-Cell,Interleukin-2

                          Therapeutic Area : Oncology

                          Study Phase : Phase I

                          Sponsor : Iovance Biotherapeutics | UPMC Hillman Cancer Center

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Autologous Pleural Infiltrating T-Cell is a Cell & Gene Therapy drug candidate, which is currently being evaluated in Phase I clinical studies for the treatment of Pleural Effusion, Malignant.

                          Product Name : Undisclosed

                          Product Type : Cell & Gene Therapy

                          Upfront Cash : Inapplicable

                          September 25, 2025

                          Lead Product(s) : Autologous Pleural Infiltrating T-Cell,Interleukin-2

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Iovance Biotherapeutics | UPMC Hillman Cancer Center

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          VMX
                          Not Confirmed
                          VMX
                          Not Confirmed

                          Details : The collaboration aims to advance SynKIR-110 gene therapy targeting Mesothelin for solid tumors.

                          Product Name : SynKIR-110

                          Product Type : Cell & Gene Therapy

                          Upfront Cash : Undisclosed

                          September 25, 2025

                          Lead Product(s) : SynKIR-110

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Verismo Therapeutics

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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