Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : NYX-2925
Therapeutic Area : Musculoskeletal
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Aptinyx Reports Results from Phase 2b Study of NYX-2925 in Fibromyalgia
Details : NYX-2925 did not achieve statistically significant separation from placebo on the study’s primary endpoint, which assessed the change from baseline in average daily pain on the numeric rating scale (NRS) during week 12.
Product Name : NYX-2925
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
December 08, 2022
Lead Product(s) : NYX-2925
Therapeutic Area : Musculoskeletal
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : NYX-2925, NMDA receptor positive allosteric modulator currently under evaluation in Phase 2b study in patients with painful DPN and fibromyalgia has also exhibited favorable safety and tolerability profile across a wide dose range in clinical studies.
Product Name : NYX-2925
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
September 02, 2022
Aptinyx Reports Results from Phase 2b Study of NYX-2925 in Painful Diabetic Peripheral Neuropathy
Details : NYX-2925, an oral NMDA receptor positive allosteric modulator did not achieve statistically significant separation from placebo on study’s primary endpoint, which assessed change from baseline in average daily pain on numeric rating scale (NRS) during ...
Product Name : NYX-2925
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
July 04, 2022
Lead Product(s) : NYX-2925
Therapeutic Area : Musculoskeletal
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Aptinyx Completes Enrollment in Phase 2b Study of NYX-2925 in Fibromyalgia
Details : The Phase 2b study enrollment completed with 305 patients and, is evaluating the efficacy and safety of NYX-2925, a novel oral NMDA receptor positive allosteric modulator in patients with fibromyalgia.
Product Name : NYX-2925
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
February 28, 2022
Lead Product(s) : NYX-2925
Therapeutic Area : Musculoskeletal
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Aptinyx Completes Enrollment in Phase 2b Study of NYX-2925 in Painful Diabetic Peripheral Neuropathy
Details : In clinical studies, NYX-2925 has demonstrated activity that aects central pain processing, resulting in alleviation of pain and other symptoms associated with chronic pain conditions.
Product Name : NYX-2925
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
October 27, 2021
Details : Under the research agreement, investigators within the institute will partner with Aptinyx, which is developing novel therapies for neurologic disorders including NYX-2925, an oral small molecule NMDA receptor modulator in development for the treatment o...
Product Name : NYX-2925
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
September 22, 2021
Aptinyx Secures $50 Million Growth Capital Credit Facility from K2 HealthVentures
Details : The funds will provide general growth as Aptinyx advances its late-stage clinical pipeline of novel NMDA modulators which includes NYX-2925, a novel, oral small molecule in development for the treatment of chronic pain.
Product Name : NYX-2925
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
September 16, 2021
Lead Product(s) : NYX-2925
Therapeutic Area : Musculoskeletal
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Aptinyx Recommences Patient Recruitment in Phase 2 Study of NYX-2925 in Patients with Fibromyalgia
Details : Aptinyx has re-activated study sites and recommenced patient recruitment in a Phase 2 study of NYX-2925 in patients with fibromyalgia. Enrollment in the study had been suspended in March 2020 due to the escalation of the COVID-19 pandemic in the United S...
Product Name : NYX-2925
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
September 28, 2020
Lead Product(s) : NYX-2925
Therapeutic Area : Musculoskeletal
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Aptinyx Announces Proposed Public Offering of Common Stock
Details : Aptinyx intends to use the net proceeds to advance the preclinical and clinical development of its novel NMDA receptor modulators, including NYX-2925, NYX-783, and NYX-458.
Product Name : NYX-2925
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
September 01, 2020