Lead Product(s) : AT-7687
Therapeutic Area : Nutrition and Weight Loss
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Antag Starts Phase 1a Trial of GIPR Antagonist AT-7687 for Obesity
Details : AT-7687 is a peptide GIP receptor antagonist designed for once-weekly subcutaneous, currently, it is being evaluated in the treatment of obesity.
Product Name : AT-7687
Product Type : Peptide
Upfront Cash : Inapplicable
April 02, 2025
Lead Product(s) : AT-7687
Therapeutic Area : Nutrition and Weight Loss
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : GUB014295
Therapeutic Area : Nutrition and Weight Loss
Study Phase : Phase I
Sponsor : AbbVie Inc
Deal Size : $2,225.0 million
Deal Type : Licensing Agreement
AbbVie, Gubra Sign License Deal to Develop Amylin Analog for Obesity
Details : Under the licensing agreement, Abbvie will hold the exclusive rights to develop GUBamy (GUB014295), a potential best-in-class, long-acting amylin analog for the treatment of obesity.
Product Name : GUBamy
Product Type : Peptide
Upfront Cash : $350.0 million
March 03, 2025
Lead Product(s) : GUB014295
Therapeutic Area : Nutrition and Weight Loss
Highest Development Status : Phase I
Sponsor : AbbVie Inc
Deal Size : $2,225.0 million
Deal Type : Licensing Agreement
Lead Product(s) : GUB014295
Therapeutic Area : Nutrition and Weight Loss
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Gubra reveals early data for once-weekly obesity asset
Details : GUBamy (GUB014295) is a long-acting amylin agonist for once weekly subcutaneous administration. It is under phase 1 clinical development for the potential treatment of obesity.
Product Name : GUBamy
Product Type : Peptide
Upfront Cash : Inapplicable
November 13, 2024
Lead Product(s) : GUB014295
Therapeutic Area : Nutrition and Weight Loss
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : BI 1820237,BI 456906
Therapeutic Area : Nutrition and Weight Loss
Study Phase : Phase I
Sponsor : Boehringer Ingelheim GmbH
Deal Size : Inapplicable
Deal Type : Inapplicable
Boehringer Drops Obesity Drug from Gubra Partnership
Details : BI 1820237 is a potent, specific peptidic NPY2R agonist in development for the treatment of overweight/obesity via once-weekly subcutaneous injection
Product Name : BI 1820237
Product Type : Peptide
Upfront Cash : Inapplicable
October 31, 2024
Lead Product(s) : BI 1820237,BI 456906
Therapeutic Area : Nutrition and Weight Loss
Highest Development Status : Phase I
Sponsor : Boehringer Ingelheim GmbH
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Liraglutide
Therapeutic Area : Nutrition and Weight Loss
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Novo's Older Obesity Drug is Safe and Effective for Children, Study Finds
Details : Saxenda is a GLP-1 receptor agonist indicated as an adjunct to a reduced-calorie diet and increased physical activity being investigated for chronic weight management in 6-12 years old patients.
Product Name : Saxenda
Product Type : Peptide
Upfront Cash : Inapplicable
October 09, 2024
Lead Product(s) : Liraglutide
Therapeutic Area : Nutrition and Weight Loss
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Amycretin
Therapeutic Area : Nutrition and Weight Loss
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Novo Nordisk Experimental Obesity Pill Has Mild-To-Moderate Side Effects in Early Trial
Details : NN9487 (amycretin) is a novel oral, unimolecular co-agonist of both GLP-1 and amylin receptors that successfully completed phase 1 trial in Japanese Participants with Obesity
Product Name : NN9487
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
October 09, 2024
Lead Product(s) : Amycretin
Therapeutic Area : Nutrition and Weight Loss
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : CK-0045
Therapeutic Area : Nutrition and Weight Loss
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Cytoki Pharma Announces Positive Phase 1 Data for CK-0045 in Cardiometabolic Risk Factors
Details : CK-0045 is a long-acting analogue of interleukin-22 (IL-22), an atypical, non-immunomodulatory cytokine that selectively targets epithelial cells, is being evaluated for obesity & type 2 diabetes.
Product Name : CK-0045
Product Type : Other Large Molecule
Upfront Cash : Inapplicable
July 23, 2024
Lead Product(s) : CK-0045
Therapeutic Area : Nutrition and Weight Loss
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Amycretin
Therapeutic Area : Nutrition and Weight Loss
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Novo Nordisk’s Obesity Pill Bests Wegovy in Early Trial
Details : NN9487 (amycretin) is a novel oral, unimolecular co-agonist of both GLP-1 and amylin receptors that successfully completed phase 1 trial in Japanese Participants with Obesity
Product Name : NN9487
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
July 03, 2024
Lead Product(s) : Amycretin
Therapeutic Area : Nutrition and Weight Loss
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Petrelintide
Therapeutic Area : Nutrition and Weight Loss
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Zealand's Petrelintide Shows Positive Phase 1b Results
Details : ZP8396 (petrelintide) is an potent long-acting amylin analogue designed to improve solubility, minimize fibrillation, holdin a potential for the treatment of overweight.
Product Name : ZP8396
Product Type : Peptide
Upfront Cash : Inapplicable
June 20, 2024
Lead Product(s) : Petrelintide
Therapeutic Area : Nutrition and Weight Loss
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : CK-0045
Therapeutic Area : Nutrition and Weight Loss
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Cytoki Pharma Doses First Patient in Phase 2 Trial of CK-0045 for Obesity and Diabetes
Details : CK-0045 is a long-acting analogue of interleukin-22 (IL-22), an atypical, non-immunomodulatory cytokine that selectively targets epithelial cells, is being evaluated for obesity & type 2 diabetes.
Product Name : CK-0045
Product Type : Other Large Molecule
Upfront Cash : Inapplicable
April 11, 2024
Lead Product(s) : CK-0045
Therapeutic Area : Nutrition and Weight Loss
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable