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alpha4\/beta2","graph1":"Psychiatry\/Psychology","graph2":"Phase IV","graph3":"NYU Langone Health","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Psychiatry","amount2New":0,"dosageForm":"Patch","sponsorNew":"NYU Langone Health \/ Undisclosed","highestDevelopmentStatusID":"11","companyTruncated":"NYU Langone Health \/ Undisclosed"},{"orgOrder":0,"company":"Johnson & Johnson Innovative Medicine","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Undisclosed","country":"U.S.A","productType":"Controlled Substance","year":"2018","type":"Inapplicable","leadProduct":"Nicotine","moa":"Neuronal acetylcholine receptor; alpha4\/beta2","graph1":"Undisclosed","graph2":"Phase I","graph3":"Johnson & Johnson Innovative Medicine","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"","amount2New":0,"dosageForm":"Spray","sponsorNew":"Johnson & Johnson Innovative Medicine \/ Undisclosed","highestDevelopmentStatusID":"6","companyTruncated":"Johnson & Johnson Innovative Medicine \/ Undisclosed"},{"orgOrder":0,"company":"Friends Research Institute","sponsor":"Rose Research Center","pharmaFlowCategory":"DU","therapeuticArea":"Psychiatry\/Psychology","country":"U.S.A","productType":"Controlled Substance","year":"2016","type":"Inapplicable","leadProduct":"Nicotine","moa":"Neuronal acetylcholine receptor; alpha4\/beta2","graph1":"Psychiatry\/Psychology","graph2":"Phase I","graph3":"Friends Research Institute","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Psychiatry","amount2New":0,"dosageForm":"Troche\/Lozenge","sponsorNew":"Friends Research Institute \/ Rose Research Center","highestDevelopmentStatusID":"6","companyTruncated":"Friends Research Institute \/ Rose Research Center"},{"orgOrder":0,"company":"NYU Langone Health","sponsor":"Asian Americans for Equality | Chinese American Planning Council | National Institute on Minority Health and Health Disparities","pharmaFlowCategory":"DU","therapeuticArea":"Psychiatry\/Psychology","country":"U.S.A","productType":"Controlled Substance","year":"2021","type":"Inapplicable","leadProduct":"Nicotine","moa":"Neuronal acetylcholine receptor; alpha4\/beta2","graph1":"Psychiatry\/Psychology","graph2":"Phase IV","graph3":"NYU Langone Health","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Psychiatry","amount2New":0,"dosageForm":"Troche\/Lozenge","sponsorNew":"NYU Langone Health \/ Asian Americans for Equality | Chinese American Planning Council | National Institute on Minority Health and Health Disparities","highestDevelopmentStatusID":"11","companyTruncated":"NYU Langone Health \/ Asian Americans for Equality | Chinese American Planning Council | National Institute on Minority Health and Health Disparities"},{"orgOrder":0,"company":"NYU Langone Health","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Psychiatry\/Psychology","country":"U.S.A","productType":"Controlled Substance","year":"2017","type":"Inapplicable","leadProduct":"Nicotine","moa":"Neuronal acetylcholine receptor; alpha4\/beta2","graph1":"Psychiatry\/Psychology","graph2":"Phase IV","graph3":"NYU Langone Health","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Psychiatry","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"NYU Langone Health \/ Undisclosed","highestDevelopmentStatusID":"11","companyTruncated":"NYU Langone Health \/ Undisclosed"},{"orgOrder":0,"company":"22nd Century Group","sponsor":"Vince & Associates Clinical Research, Inc.","pharmaFlowCategory":"DU","therapeuticArea":"Undisclosed","country":"U.S.A","productType":"Controlled Substance","year":"2018","type":"Inapplicable","leadProduct":"Nicotine","moa":"Neuronal acetylcholine receptor; alpha4\/beta2","graph1":"Undisclosed","graph2":"Phase I","graph3":"22nd Century Group","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"22nd Century Group \/ Vince & Associates Clinical Research, Inc.","highestDevelopmentStatusID":"6","companyTruncated":"22nd Century Group \/ Vince & Associates Clinical Research, Inc."},{"orgOrder":0,"company":"22nd Century Group","sponsor":"Vince & Associates Clinical Research, Inc.","pharmaFlowCategory":"DU","therapeuticArea":"Undisclosed","country":"U.S.A","productType":"Controlled Substance","year":"2018","type":"Inapplicable","leadProduct":"Nicotine","moa":"Neuronal acetylcholine receptor; alpha4\/beta2","graph1":"Undisclosed","graph2":"Phase I","graph3":"22nd Century Group","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"22nd Century Group \/ Vince & Associates Clinical Research, Inc.","highestDevelopmentStatusID":"6","companyTruncated":"22nd Century Group \/ Vince & Associates Clinical Research, Inc."},{"orgOrder":0,"company":"Johnson & Johnson","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Psychiatry\/Psychology","country":"U.S.A","productType":"Controlled Substance","year":"2010","type":"Inapplicable","leadProduct":"Nicotine","moa":"Neuronal acetylcholine receptor; alpha4\/beta2","graph1":"Psychiatry\/Psychology","graph2":"Undisclosed","graph3":"Johnson & Johnson","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Psychiatry","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Johnson & Johnson \/ Undisclosed","highestDevelopmentStatusID":"1","companyTruncated":"Johnson & Johnson \/ Undisclosed"},{"orgOrder":0,"company":"22nd Century Group","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Psychiatry\/Psychology","country":"U.S.A","productType":"Controlled Substance","year":"2022","type":"Inapplicable","leadProduct":"Nicotine","moa":"Neuronal acetylcholine receptor; alpha4\/beta2","graph1":"Psychiatry\/Psychology","graph2":"Approved FDF","graph3":"22nd Century Group","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Psychiatry","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"22nd Century Group \/ Undisclosed","highestDevelopmentStatusID":"15","companyTruncated":"22nd Century Group \/ Undisclosed"},{"orgOrder":0,"company":"CV Science","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Psychiatry\/Psychology","country":"U.S.A","productType":"Controlled Substance","year":"2023","type":"Inapplicable","leadProduct":"Nicotine","moa":"||Neuronal acetylcholine receptor; alpha4\/beta2","graph1":"Psychiatry\/Psychology","graph2":"Phase I","graph3":"CV Science","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Psychiatry","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"CV Science \/ Undisclosed","highestDevelopmentStatusID":"6","companyTruncated":"CV Science \/ Undisclosed"},{"orgOrder":0,"company":"University of Auckland, New Zealand","sponsor":"Health New Zealand Ltd, Christchurch, New Zealand | Auckland District Health Board","pharmaFlowCategory":"DU","therapeuticArea":"Psychiatry\/Psychology","country":"NEW ZEALAND","productType":"Controlled Substance","year":"2015","type":"Inapplicable","leadProduct":"Nicotine","moa":"Neuronal acetylcholine receptor; alpha4\/beta2","graph1":"Psychiatry\/Psychology","graph2":"Phase III","graph3":"University of Auckland, New Zealand","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Psychiatry","amount2New":0,"dosageForm":"Liquid","sponsorNew":"University of Auckland, New Zealand \/ Health New Zealand Ltd, Christchurch, New Zealand | Auckland District Health Board","highestDevelopmentStatusID":"10","companyTruncated":"University of Auckland, New Zealand \/ Health New Zealand Ltd, Christchurch, New Zealand | Auckland District Health Board"},{"orgOrder":0,"company":"James Boyd","sponsor":"Michael J. Fox Foundation | Parkinson Study Group | International Parkinson Fonds | German Parkinson Study Group | German Parkinson Society | Philipps University Marburg","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"","productType":"Controlled Substance","year":"2012","type":"Inapplicable","leadProduct":"Nicotine","moa":"Neuronal acetylcholine receptor; alpha4\/beta2","graph1":"Neurology","graph2":"Phase II","graph3":"James Boyd","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Patch","sponsorNew":"James Boyd \/ Michael J. Fox Foundation | Parkinson Study Group | International Parkinson Fonds | German Parkinson Study Group | German Parkinson Society | Philipps University Marburg","highestDevelopmentStatusID":"8","companyTruncated":"James Boyd \/ Michael J. Fox Foundation | Parkinson Study Group | International Parkinson Fonds | German Parkinson Study Group | German Parkinson Society | Philipps University Marburg"},{"orgOrder":0,"company":"Mark Vander Weg","sponsor":"Iowa City VA Health Care System","pharmaFlowCategory":"DU","therapeuticArea":"Psychiatry\/Psychology","country":"","productType":"Controlled Substance","year":"2016","type":"Inapplicable","leadProduct":"Nicotine","moa":"Neuronal acetylcholine receptor; alpha4\/beta2","graph1":"Psychiatry\/Psychology","graph2":"Undisclosed","graph3":"Mark Vander Weg","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Psychiatry","amount2New":0,"dosageForm":"Patch","sponsorNew":"Mark Vander Weg \/ Iowa City VA Health Care System","highestDevelopmentStatusID":"1","companyTruncated":"Mark Vander Weg \/ Iowa City VA Health Care System"},{"orgOrder":0,"company":"Jed E. Rose","sponsor":"Philip Morris USA, Inc | National Institute on Drug Abuse","pharmaFlowCategory":"DU","therapeuticArea":"Psychiatry\/Psychology","country":"","productType":"Controlled Substance","year":"2013","type":"Inapplicable","leadProduct":"Nicotine","moa":"Neuronal acetylcholine receptor; alpha4\/beta2","graph1":"Psychiatry\/Psychology","graph2":"Phase II","graph3":"Jed E. Rose","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Psychiatry","amount2New":0,"dosageForm":"Patch","sponsorNew":"Jed E. Rose \/ Philip Morris USA, Inc | National Institute on Drug Abuse","highestDevelopmentStatusID":"8","companyTruncated":"Jed E. Rose \/ Philip Morris USA, Inc | National Institute on Drug Abuse"},{"orgOrder":0,"company":"Contract Research Organization el AB","sponsor":"Swedish Match AB","pharmaFlowCategory":"DU","therapeuticArea":"Undisclosed","country":"","productType":"Controlled Substance","year":"2010","type":"Inapplicable","leadProduct":"Nicotine","moa":"Neuronal acetylcholine receptor; alpha4\/beta2","graph1":"Undisclosed","graph2":"Phase I\/ Phase II","graph3":"Contract Research Organization el AB","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"","amount2New":0,"dosageForm":"Pouch","sponsorNew":"Contract Research Organization el AB \/ Swedish Match AB","highestDevelopmentStatusID":"7","companyTruncated":"Contract Research Organization el AB \/ Swedish Match AB"},{"orgOrder":0,"company":"Contract Research Organization el AB","sponsor":"Commitum AB","pharmaFlowCategory":"DU","therapeuticArea":"Psychiatry\/Psychology","country":"","productType":"Controlled Substance","year":"2013","type":"Inapplicable","leadProduct":"Nicotine","moa":"Neuronal acetylcholine receptor; alpha4\/beta2","graph1":"Psychiatry\/Psychology","graph2":"Phase I\/ Phase II","graph3":"Contract Research Organization el AB","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Psychiatry","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Contract Research Organization el AB \/ Commitum AB","highestDevelopmentStatusID":"7","companyTruncated":"Contract Research Organization el AB \/ Commitum AB"},{"orgOrder":0,"company":"University of California, Los Angeles","sponsor":"Philip Morris USA, Inc","pharmaFlowCategory":"DU","therapeuticArea":"Psychiatry\/Psychology","country":"U.S.A","productType":"Miscellaneous","year":"2011","type":"Inapplicable","leadProduct":"Nicotine","moa":"Neuronal acetylcholine receptor; alpha4\/beta2","graph1":"Psychiatry\/Psychology","graph2":"Phase I","graph3":"University of California, Los Angeles","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Psychiatry","amount2New":0,"dosageForm":"Patch","sponsorNew":"University of California, Los Angeles \/ Philip Morris USA, Inc","highestDevelopmentStatusID":"6","companyTruncated":"University of California, Los Angeles \/ Philip Morris USA, Inc"},{"orgOrder":0,"company":"Centre for Addiction and Mental Health","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Psychiatry\/Psychology","country":"CANADA","productType":"Miscellaneous","year":"2011","type":"Inapplicable","leadProduct":"Nicotine","moa":"Neuronal acetylcholine receptor; alpha4\/beta2","graph1":"Psychiatry\/Psychology","graph2":"Undisclosed","graph3":"Centre for Addiction and Mental Health","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Psychiatry","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Centre for Addiction and Mental Health \/ Undisclosed","highestDevelopmentStatusID":"1","companyTruncated":"Centre for Addiction and Mental Health \/ Undisclosed"},{"orgOrder":0,"company":"Montefiore Medical Center","sponsor":"Westat | Johns Hopkins University","pharmaFlowCategory":"DU","therapeuticArea":"Psychiatry\/Psychology","country":"U.S.A","productType":"Miscellaneous","year":"2016","type":"Inapplicable","leadProduct":"Nicotine","moa":"Neuronal acetylcholine receptor; alpha4\/beta2","graph1":"Psychiatry\/Psychology","graph2":"Undisclosed","graph3":"Montefiore Medical Center","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Psychiatry","amount2New":0,"dosageForm":"Patch","sponsorNew":"Montefiore Medical Center \/ Westat | Johns Hopkins University","highestDevelopmentStatusID":"1","companyTruncated":"Montefiore Medical Center \/ Westat | Johns Hopkins University"},{"orgOrder":0,"company":"Temple University","sponsor":"NORTH","pharmaFlowCategory":"DU","therapeuticArea":"Psychiatry\/Psychology","country":"U.S.A","productType":"Miscellaneous","year":"2015","type":"Inapplicable","leadProduct":"Nicotine","moa":"Neuronal acetylcholine receptor; alpha4\/beta2","graph1":"Psychiatry\/Psychology","graph2":"Undisclosed","graph3":"Temple University","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Psychiatry","amount2New":0,"dosageForm":"Troche\/Lozenge","sponsorNew":"Temple University \/ NORTH","highestDevelopmentStatusID":"1","companyTruncated":"Temple University \/ NORTH"}]

Find Clinical Drug Pipeline Developments & Deals for Nicotine D-Bitartrate Dihydrate

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                          01

                          Lead Product(s) : Nicotine

                          Therapeutic Area : Psychiatry/Psychology

                          Study Phase : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Nicotine polacrilex lozenges are an important addition to our current offering of nicotine replacement therapy including nicotine transdermal system patches, sold as Habitrol® brand and various store brands.

                          Product Name : Nicotine Polacrilex-Generic

                          Product Type : Controlled Substance

                          Upfront Cash : Inapplicable

                          July 14, 2020

                          Lead Product(s) : Nicotine

                          Therapeutic Area : Psychiatry/Psychology

                          Highest Development Status : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Dr Reddy Company Banner

                          02

                          Ottawa Heart Institute Research Corporation

                          Country arrow
                          OTS 2025
                          Not Confirmed

                          Ottawa Heart Institute Research Corporation

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                          OTS 2025
                          Not Confirmed

                          Lead Product(s) : Nicotine

                          Therapeutic Area : Psychiatry/Psychology

                          Study Phase : Phase IV

                          Sponsor : Sun Life Assurance Company of Canada | Vita Aid Professional Therapeutics | Lumino Health Pharmacy

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Nicotine is a Controlled Substance drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Tobacco Use Disorder.

                          Product Name : Undisclosed

                          Product Type : Controlled Substance

                          Upfront Cash : Inapplicable

                          February 18, 2025

                          Lead Product(s) : Nicotine

                          Therapeutic Area : Psychiatry/Psychology

                          Highest Development Status : Phase IV

                          Sponsor : Sun Life Assurance Company of Canada | Vita Aid Professional Therapeutics | Lumino Health Pharmacy

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : RespiRx is a drug device combination product that is the first truly inhalable nicotine replacement therapy (NRT) to assist smokers attempting to quit smoking.

                          Product Name : RespiRx

                          Product Type : Controlled Substance

                          Upfront Cash : Inapplicable

                          January 07, 2025

                          Lead Product(s) : Nicotine

                          Therapeutic Area : Psychiatry/Psychology

                          Highest Development Status : Phase I

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : RespiRx is a drug device combination product that is the first truly inhalable nicotine replacement therapy (NRT) to assist smokers attempting to quit smoking.

                          Product Name : RespiRx

                          Product Type : Controlled Substance

                          Upfront Cash : Inapplicable

                          October 01, 2024

                          Lead Product(s) : Nicotine

                          Therapeutic Area : Psychiatry/Psychology

                          Highest Development Status : IND Enabling

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          Rose Research Center

                          Country arrow
                          OTS 2025
                          Not Confirmed

                          Rose Research Center

                          Country arrow
                          OTS 2025
                          Not Confirmed

                          Details : Nicorette (Nicotine) is a Controlled Substance drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Smoking Cessation.

                          Product Name : Nicorette

                          Product Type : Controlled Substance

                          Upfront Cash : Inapplicable

                          August 15, 2024

                          Lead Product(s) : Nicotine

                          Therapeutic Area : Psychiatry/Psychology

                          Highest Development Status : Phase III

                          Sponsor : Global Action to End Smoking

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          Johns Hopkins University

                          Country arrow
                          OTS 2025
                          Not Confirmed

                          Johns Hopkins University

                          Country arrow
                          OTS 2025
                          Not Confirmed

                          Details : Nicotine is a Controlled Substance drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Tobacco Use Disorder.

                          Product Name : Undisclosed

                          Product Type : Controlled Substance

                          Upfront Cash : Inapplicable

                          August 09, 2024

                          Lead Product(s) : Nicotine

                          Therapeutic Area : Psychiatry/Psychology

                          Highest Development Status : Phase IV

                          Sponsor : Maryland Cigarette Restitution Fund | Walgreens

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : Through the acquisition, Reddy will leverage the NRT portfolio, which includes Nicotinell (nicotine) in various formats such as lozenges, patches, and gum, across all applicable global market.

                          Product Name : Nicotinell

                          Product Type : Controlled Substance

                          Upfront Cash : $579.8 million

                          June 26, 2024

                          Lead Product(s) : Nicotine

                          Therapeutic Area : Psychiatry/Psychology

                          Highest Development Status : Approved FDF

                          Sponsor : Dr. Reddy\'s Laboratories

                          Deal Size : $632.9 million

                          Deal Type : Acquisition

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                          08

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : MHRA approved first and only nicotine inhaler enabling rapid absorption via the lungs to help smokers replace, cut down, and ultimately quit smoking.

                          Product Name : Undisclosed

                          Product Type : Controlled Substance

                          Upfront Cash : Inapplicable

                          June 25, 2024

                          Lead Product(s) : Nicotine

                          Therapeutic Area : Psychiatry/Psychology

                          Highest Development Status : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          Rose Research Center

                          Country arrow
                          OTS 2025
                          Not Confirmed

                          Rose Research Center

                          Country arrow
                          OTS 2025
                          Not Confirmed

                          Details : Nicorette (Nicotine) is a Controlled Substance drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Smoking Cessation.

                          Product Name : Nicorette

                          Product Type : Controlled Substance

                          Upfront Cash : Inapplicable

                          October 18, 2023

                          Lead Product(s) : Nicotine

                          Therapeutic Area : Psychiatry/Psychology

                          Highest Development Status : Phase III

                          Sponsor : Foundation for a Smoke Free World

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : U.S. Food and Drug Administration approved OTC, nicotine coated mint lozenges, works by reducing withdrawal symptoms in consumers who are trying to quit smoking.

                          Product Name : Nicorette-Generic

                          Product Type : Controlled Substance

                          Upfront Cash : Inapplicable

                          May 16, 2023

                          Lead Product(s) : Nicotine

                          Therapeutic Area : Psychiatry/Psychology

                          Highest Development Status : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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