Neurology | New Developments | UNITED STATES

PicnicHealth

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Roche, Genentech Employ PicnicHealth to Tap into MS Patient Data

Lead Product(s): Undisclosed

Therapeutic Area: Neurology Product Name: Undisclosed

Highest Development Status: Undisclosed Product Type: Undisclosed

Partner/Sponsor/Collaborator: F. Hoffmann-La Roche

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Partnership July 17, 2020

Details:

Following initial efforts focused on multiple sclerosis (MS), PicnicHealth, Roche and Genentech recently expanded their collaboration to support Huntington’s disease (HD), paroxysmal nocturnal hemoglobinuria (PNH), and hemophilia.

Pocono Coated Product

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Nutriband Acquires Transdermal and Health Product Manufacturing Business

Lead Product(s): Opioid based transdermal medications

Therapeutic Area: Neurology Product Name: Undisclosed

Highest Development Status: Undisclosed Product Type: Small molecule

Partner/Sponsor/Collaborator: Nutriband

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Acquisition July 16, 2020

Details:

With this acquisition Pocono plans to consolidate capabilities at both facilities to expand on enhancing revenue stream opportunities and in-house product development, specifically our abuse deterrent technology for opioid based transdermal medications.

Codiak BioSciences

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Sarepta and Codiak BioSciences to develop rare disease therapies

Lead Product(s): Gene therapy

Therapeutic Area: Neurology Product Name: Undisclosed

Highest Development Status: Undisclosed Product Type: Cell and Gene therapy

Partner/Sponsor/Collaborator: Sarepta Therapeutics

Deal Size: Undisclosed Upfront Cash: $72.5 million

Deal Type: Collaboration June 23, 2020

Details:

Alliance to explore the utility of engineered exosomes developed with Codiak’s engEx™ Platform to deliver gene therapy, gene editing and RNA technologies.

Vizient

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Vizient Announces Novaplus Enhanced Supply Agreement with Pfizer for Six Essential Medications

Lead Product(s): Dexmedetomidine Hydrochloride

Therapeutic Area: Neurology Product Name: Precedex

Highest Development Status: Undisclosed Product Type: Small molecule

Partner/Sponsor/Collaborator: Pfizer Inc

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Agreement June 22, 2020

Details:

Vizient has signed an agreement with Pfizer to add six drugs identified as “essential medications” to its Novaplus® Enhanced Supply Program, part of Vizient’s private label pharmacy solution.

Engrail Therapeutics

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Engrail Therapeutics Raises $32 Million in Series A Financing

Lead Product(s): ENX-101

Therapeutic Area: Neurology Product Name: ENX-101

Highest Development Status: Undisclosed Product Type: Undisclosed

Partner/Sponsor/Collaborator: Nan Fung Life Sciences

Deal Size: $32.0 million Upfront Cash: Undisclosed

Deal Type: Series A Financing June 18, 2020

Details:

The Company plans to use the proceeds from the financing to support the clinical development of its first pipeline asset, ENX-101, a sub-type selective GABA A modulator.

Cyclo Therapeutics

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Cyclo Therapeutics Reports on Eighteen Month Expanded Access Program in Single Alzheimer’s Patient

Lead Product(s): Hydroxypropyl-Beta Cyclodextrin

Therapeutic Area: Neurology Product Name: Trappsol Cyclo

Highest Development Status: Undisclosed Product Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable June 17, 2020

Details:

The final report to FDA states that the drug showed a favorable safety profile as well as encouraging observations of benefit. Safety was monitored by MRIs, ECGs, laboratory safety assessments, and adverse events, all of which supported a favorable safety profile.

Autobahn Therapeutics

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Autobahn Therapeutics Launches with $76 Million Series B Financing to Develop Next Generation Therapies for CNS Disorders

Lead Product(s): ABX-002

Therapeutic Area: Neurology Product Name: Undisclosed

Highest Development Status: Undisclosed Product Type: Small molecule

Partner/Sponsor/Collaborator: ARCH Venture Partners

Deal Size: $76.0 million Upfront Cash: Undisclosed

Deal Type: Series B Financing June 09, 2020

Details:

Proceeds will be used to advance Autobahn’s lead program candidate, ABX-002, a thyroid hormone receptor beta agonist therapy for the treatment of multiple sclerosis (MS) and adrenomyeloneuropathy (AMN).

Axial Biotherapeutics, Inc

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Axial Biotherapeutics to Present Virtual Presentation at American Society of Clinical Psychopharmacology (ASCP) 2020 Annual Meeting

Lead Product(s): Undisclosed

Therapeutic Area: Neurology Product Name: Undisclosed

Highest Development Status: Undisclosed Product Type: Undisclosed

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable May 22, 2020

Details:

Presentation will focus on the development of novel therapeutics focused on treating Central Nervous System (CNS) indications via the gut-brain axis at the American Society of Clinical Psychopharmacology (ASCP).

Axcella Health

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Axcella Announces Closing of Public Offering of Common Stock, Including Full Exercise of Underwriters’ Option

Lead Product(s): AXA1665

Therapeutic Area: Neurology Product Name: Undisclosed

Highest Development Status: Undisclosed Product Type: Small molecule

Partner/Sponsor/Collaborator: J.P. Morgan

Deal Size: $60.1 million Upfront Cash: Undisclosed

Deal Type: Public Offering May 18, 2020

Details:

Axcella intends to use the net proceeds to advance its current liver programs, including its planned IND filing for AXA1665 and ensuing initiation of a Clinical Trial and its planned IND filing for AXA1125 in adults and pediatric patients and trial of AXA4010.

Cyclo Therapeutics

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Cyclo Therapeutics Reports Publication of International Patent Application for Treatment of Alzheimer’s Disease

Lead Product(s): Hydroxypropyl-Beta Cyclodextrin

Therapeutic Area: Neurology Product Name: Undisclosed

Highest Development Status: Undisclosed Product Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable May 14, 2020

Details:

The patent application describes treating Alzheimer’s Disease with the Company’s Trappsol® Cyclo™ hydroxypropyl beta cyclodextrin product.

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Find Novel Neurology Drugs in Clinical Development in UNITED STATES

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Product Type

Companies

PicnicHealth

Roche, Genentech Employ PicnicHealth to Tap into MS Patient Data

Pocono Coated Product

Nutriband Acquires Transdermal and Health Product Manufacturing Business

Codiak BioSciences

Sarepta and Codiak BioSciences to develop rare disease therapies

Vizient

Vizient Announces Novaplus Enhanced Supply Agreement with Pfizer for Six Essential Medications

Engrail Therapeutics

Engrail Therapeutics Raises $32 Million in Series A Financing

Cyclo Therapeutics

Cyclo Therapeutics Reports on Eighteen Month Expanded Access Program in Single Alzheimer’s Patient

Autobahn Therapeutics

Autobahn Therapeutics Launches with $76 Million Series B Financing to Develop Next Generation Therapies for CNS Disorders

Axial Biotherapeutics, Inc

Axial Biotherapeutics to Present Virtual Presentation at American Society of Clinical Psychopharmacology (ASCP) 2020 Annual Meeting

Axcella Health

Axcella Announces Closing of Public Offering of Common Stock, Including Full Exercise of Underwriters’ Option

Cyclo Therapeutics

Cyclo Therapeutics Reports Publication of International Patent Application for Treatment of Alzheimer’s Disease