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                          Therapeutic Area by Lead Product

                          Study Phase by Lead Product

                          Company by Lead Product

                          Top Deals by Deal Size (USD bn)

                          01

                          Lead Product(s) : COYA 302,Abatacept

                          Therapeutic Area : Neurology

                          Study Phase : Preclinical

                          Sponsor : Coya Therapeutics

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

                          Details : Under the agreement, Coya will in-license the proposed Abatacept biosimilar for the development of Coya’s combination product for neurodegenerative diseases, COYA 302, an investigational combination biologic for subcutaneous administration, comprised o...

                          Product Name : Undisclosed

                          Product Type : Protein

                          Upfront Cash : Undisclosed

                          March 20, 2023

                          Lead Product(s) : COYA 302,Abatacept

                          Therapeutic Area : Neurology

                          Highest Development Status : Preclinical

                          Sponsor : Coya Therapeutics

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

                          Dr Reddy Company Banner

                          02

                          Details : The funding will be used to develop an assay platform and novel antibodies to support the treatment, prevention, and early diagnosis of Alzheimer’s disease and other tauopathies.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          October 08, 2020

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Neurology

                          Highest Development Status : Preclinical

                          Sponsor : SBIR

                          Deal Size : Undisclosed

                          Deal Type : Funding

                          Cayman

                          03

                          Aquaexpo
                          Not Confirmed
                          Aquaexpo
                          Not Confirmed

                          Details : YB002 is a first-in-class gene therapy designed to safely and transiently express Yamanaka factors in the brain. It is being evaluated for the treatment of alzheimer's disease.

                          Product Name : YB002

                          Product Type : Cell & Gene Therapy

                          Upfront Cash : Inapplicable

                          September 25, 2025

                          Lead Product(s) : YB002

                          Therapeutic Area : Neurology

                          Highest Development Status : Preclinical

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          Aquaexpo
                          Not Confirmed
                          Aquaexpo
                          Not Confirmed

                          Details : TGR-63 is the company's investigational small-molecule drug candidate which is being evaluated for the treatment of Alzheimer's disease.

                          Product Name : TGR-63

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          September 24, 2025

                          Lead Product(s) : TGR-63

                          Therapeutic Area : Neurology

                          Highest Development Status : Preclinical

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          Aquaexpo
                          Not Confirmed
                          Aquaexpo
                          Not Confirmed

                          Details : SenoVax (SNVL-31) is the first-in-class senolytic immunotherapy that utilizes patient-specific to train the immune system to clear senescent cells, for chronic traumatic encephalopathy.

                          Product Name : SenoVax

                          Product Type : Vaccine

                          Upfront Cash : Inapplicable

                          September 24, 2025

                          Lead Product(s) : SNVL-31

                          Therapeutic Area : Neurology

                          Highest Development Status : Preclinical

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          Aquaexpo
                          Not Confirmed
                          Aquaexpo
                          Not Confirmed

                          Details : Angelini Pharma and Sovargen will collaboratively lead the pre-clinical development efforts for SVG105, a potentially first-in-class anti-sense oligonucleotide technology to target mTOR pathways.

                          Product Name : SVG105

                          Product Type : Oligonucleotide

                          Upfront Cash : Undisclosed

                          September 22, 2025

                          Lead Product(s) : SVG105

                          Therapeutic Area : Neurology

                          Highest Development Status : Preclinical

                          Sponsor : Angelini Pharma

                          Deal Size : $550.0 million

                          Deal Type : Agreement

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                          07

                          Aquaexpo
                          Not Confirmed
                          Aquaexpo
                          Not Confirmed

                          Details : Klothonova will leverage Austrianova's cellencapsulation technology to develop and commercialize treatments targeting Alzheimer's, cancer, kidney, heart and other age-related conditions.

                          Product Name : Undisclosed

                          Product Type : Cell & Gene Therapy

                          Upfront Cash : Undisclosed

                          September 18, 2025

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Neurology

                          Highest Development Status : Preclinical

                          Sponsor : Klothonova

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

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                          08

                          Aquaexpo
                          Not Confirmed
                          Aquaexpo
                          Not Confirmed

                          Details : The proceeds will support development of its innovative TNF-alpha inhibitor NN-840 program for Alzheimer’s disease and other neurodegenerative conditions.

                          Product Name : NN-840

                          Product Type : Antibody, Unconjugated

                          Upfront Cash : Undisclosed

                          September 10, 2025

                          Lead Product(s) : NN-840

                          Therapeutic Area : Neurology

                          Highest Development Status : Preclinical

                          Sponsor : National Institutes of Health

                          Deal Size : $2.5 million

                          Deal Type : Funding

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                          09

                          Aquaexpo
                          Not Confirmed
                          Aquaexpo
                          Not Confirmed

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Neurology

                          Study Phase : Preclinical

                          Sponsor : Michael J. Fox Foundation for Parkinson’s Research

                          Deal Size : $2.9 million

                          Deal Type : Funding

                          Details : The funding will support the preclinical and translational development of Lysoway’s novel, highly brain-penetrant small molecule TRPML1 agonist.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Undisclosed

                          August 05, 2025

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Neurology

                          Highest Development Status : Preclinical

                          Sponsor : Michael J. Fox Foundation for Parkinson’s Research

                          Deal Size : $2.9 million

                          Deal Type : Funding

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                          10

                          Aquaexpo
                          Not Confirmed
                          Aquaexpo
                          Not Confirmed

                          Details : Through the collaboration, City will leverage its next-generation RNAi engineering technologies to develop an RNAi trigger molecule combined with proprietary drug delivery technology from Biogen.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : $16.0 million

                          May 27, 2025

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Neurology

                          Highest Development Status : Preclinical

                          Sponsor : Biogen

                          Deal Size : $1,046.0 million

                          Deal Type : Collaboration

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