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Inapplicable"},{"orgOrder":0,"company":"Capsida","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2025","type":"Inapplicable","leadProduct":"CAP-003","moa":"GCase","graph1":"Neurology","graph2":"Preclinical","graph3":"Capsida","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Capsida \/ Inapplicable","highestDevelopmentStatusID":"4","companyTruncated":"Capsida \/ Inapplicable"},{"orgOrder":0,"company":"Scribe Therapeutics","sponsor":"Prevail Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2025","type":"Collaboration","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Neurology","graph2":"Preclinical","graph3":"Scribe Therapeutics","amount2":1.5800000000000001,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Neurology","amount2New":1.5800000000000001,"dosageForm":"Undisclosed","sponsorNew":"Scribe Therapeutics \/ Prevail Therapeutics","highestDevelopmentStatusID":"4","companyTruncated":"Scribe Therapeutics \/ Prevail Therapeutics"},{"orgOrder":0,"company":"Hoth Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"U.S.A","productType":"Other Small Molecule","year":"2025","type":"Inapplicable","leadProduct":"HT-ALZ","moa":"NK-1 receptor","graph1":"Neurology","graph2":"Preclinical","graph3":"Hoth Therapeutics","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Oral Film","sponsorNew":"Hoth Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"4","companyTruncated":"Hoth Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"Sangamo Therapeutics","sponsor":"Eli Lilly","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2025","type":"Licensing Agreement","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Neurology","graph2":"Preclinical","graph3":"Sangamo Therapeutics","amount2":1.4199999999999999,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Neurology","amount2New":1.4199999999999999,"dosageForm":"Intravenous","sponsorNew":"Sangamo Therapeutics \/ Eli Lilly","highestDevelopmentStatusID":"4","companyTruncated":"Sangamo Therapeutics \/ Eli Lilly"},{"orgOrder":0,"company":"Alchemab","sponsor":"Eli Lilly","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"UNITED KINGDOM","productType":"Antibody","year":"2025","type":"Licensing Agreement","leadProduct":"ATLX-1282","moa":"UNC5C","graph1":"Neurology","graph2":"Preclinical","graph3":"Alchemab","amount2":0.41999999999999998,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Neurology","amount2New":0.41999999999999998,"dosageForm":"Undisclosed","sponsorNew":"Alchemab \/ Eli Lilly","highestDevelopmentStatusID":"4","companyTruncated":"Alchemab \/ Eli Lilly"},{"orgOrder":0,"company":"Channel Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"U.S.A","productType":"Other Small Molecule","year":"2025","type":"Inapplicable","leadProduct":"CT2000","moa":"NaV1.7 channel","graph1":"Neurology","graph2":"Preclinical","graph3":"Channel Therapeutics","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Ophthalmic Solution","sponsorNew":"Channel Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"4","companyTruncated":"Channel Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"Revive Therapeutics","sponsor":"DRDC","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"CANADA","productType":"Other Small Molecule","year":"2025","type":"Inapplicable","leadProduct":"Bucillamine","moa":"Glutathione","graph1":"Neurology","graph2":"Preclinical","graph3":"Revive Therapeutics","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Revive Therapeutics \/ DRDC","highestDevelopmentStatusID":"4","companyTruncated":"Revive Therapeutics \/ DRDC"},{"orgOrder":0,"company":"Polyrizon","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"ISRAEL","productType":"Other Small Molecule","year":"2025","type":"Inapplicable","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Neurology","graph2":"Preclinical","graph3":"Polyrizon","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Nasal","sponsorNew":"Polyrizon \/ Inapplicable","highestDevelopmentStatusID":"4","companyTruncated":"Polyrizon \/ Inapplicable"},{"orgOrder":0,"company":"City Therapeutics","sponsor":"Biogen","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"U.S.A","productType":"Oligonucleotide","year":"2025","type":"Collaboration","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Neurology","graph2":"Preclinical","graph3":"City Therapeutics","amount2":0.050000000000000003,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Neurology","amount2New":0.050000000000000003,"dosageForm":"Undisclosed","sponsorNew":"City Therapeutics \/ Biogen","highestDevelopmentStatusID":"4","companyTruncated":"City Therapeutics \/ Biogen"}]

    Find Novel Neurology Drugs in Preclinical Development in UNITED STATES

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                            01

                            Dr. Reddy's Laboratories

                            India
                            CPhI Korea
                            Attending
                            • fda
                            • EDQM
                            • WHO-GMP
                            Virtual BoothDRL offers a portfolio of products & services, including APIs, CMO services, generics, biosimilars & differentiated formulations.

                            Lead Product(s) : COYA 302,Abatacept

                            Therapeutic Area : Neurology

                            Study Phase : Preclinical

                            Sponsor : Coya Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Coya Therapeutics, Inc. Announces an Agreement with Dr. Reddy’s Laboratories, Ltd. to License its proposed b...

                            Details : Under the agreement, Coya will in-license the proposed Abatacept biosimilar for the development of Coya’s combination product for neurodegenerative diseases, COYA 302, an investigational combination biologic for subcutaneous administration, comprised o...

                            Product Name : COYA 302

                            Product Type : Protein

                            Upfront Cash : Undisclosed

                            March 20, 2023

                            Lead Product(s) : COYA 302,Abatacept

                            Therapeutic Area : Neurology

                            Highest Development Status : Preclinical

                            Sponsor : Coya Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

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                            02

                            Polpharma

                            Poland
                            ChemOutsourcing
                            Attending
                            • fda
                            • EDQM
                            • WHO-GMP
                            Virtual BoothPolpharma is a Polish CDMO of APIs and a significant European API producer, delivering products to companies worldwide.

                            Lead Product(s) : PKL-021

                            Therapeutic Area : Neurology

                            Study Phase : Preclinical

                            Sponsor : Pikralida biopharmaceutical

                            Deal Size : Undisclosed

                            Deal Type : Partnership

                            DEALS_DEV arrow-down

                            Polpharma Partners with Pikralida Biopharmaceutical Start-Up

                            Details : The partnership involves manufacturing of the drug substance of the clinical candidate PKL-021, needed to support the preclinical research program and the production of an investigational medicinal product for the phase one clinical trial.

                            Product Name : PKL-021

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            July 19, 2022

                            Lead Product(s) : PKL-021

                            Therapeutic Area : Neurology

                            Highest Development Status : Preclinical

                            Sponsor : Pikralida biopharmaceutical

                            Deal Size : Undisclosed

                            Deal Type : Partnership

                            Polpharma CB

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                            03

                            Cayman Chemical Company Inc

                            U.S.A
                            Discovery Europe
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
                            Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Neurology

                            Study Phase : Preclinical

                            Sponsor : SBIR

                            Deal Size : Undisclosed

                            Deal Type : Funding

                            DEALS_DEV arrow-down

                            Cayman Receives SBIR Grant for Alzheimer’s Research

                            Details : The funding will be used to develop an assay platform and novel antibodies to support the treatment, prevention, and early diagnosis of Alzheimer’s disease and other tauopathies.

                            Product Name : Undisclosed

                            Product Type : Antibody

                            Upfront Cash : Undisclosed

                            August 10, 2020

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Neurology

                            Highest Development Status : Preclinical

                            Sponsor : SBIR

                            Deal Size : Undisclosed

                            Deal Type : Funding

                            Cayman

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                            04

                            City Therapeutics

                            U.S.A arrow
                            Discovery Europe
                            Not Confirmed

                            City Therapeutics

                            U.S.A arrow
                            Discovery Europe
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Neurology

                            Study Phase : Preclinical

                            Sponsor : Biogen

                            Deal Size : $1,046.0 million

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Biogen and City Therapeutics Partner On RNAi-Based Therapy Development

                            Details : Through the collaboration, City will leverage its next-generation RNAi engineering technologies to develop an RNAi trigger molecule combined with proprietary drug delivery technology from Biogen.

                            Product Name : Undisclosed

                            Product Type : Oligonucleotide

                            Upfront Cash : $16.0 million

                            May 27, 2025

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Neurology

                            Highest Development Status : Preclinical

                            Sponsor : Biogen

                            Deal Size : $1,046.0 million

                            Deal Type : Collaboration

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                            05

                            Polyrizon

                            Israel arrow
                            Discovery Europe
                            Not Confirmed

                            Polyrizon

                            Israel arrow
                            Discovery Europe
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Neurology

                            Study Phase : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Polyrizon Eyes $3.15B Epilepsy Market with Rescue Drug in Preclinical Stage

                            Details : Intranasal Benzodiazepines (BZDs) is being developed by Polyrizon as a first-line treatment for acute repetitive seizures (ARS) and status epilepticus, using its proprietary drug delivery platform.

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            May 13, 2025

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Neurology

                            Highest Development Status : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Revive Therapeutics

                            Canada arrow
                            Discovery Europe
                            Not Confirmed

                            Revive Therapeutics

                            Canada arrow
                            Discovery Europe
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
                            Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.

                            Lead Product(s) : Bucillamine

                            Therapeutic Area : Neurology

                            Study Phase : Preclinical

                            Sponsor : DRDC

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Revive Updates Bucillamine Research for Nerve Agent Exposure Treatment

                            Details : Bucillamine is an oral potent thiol donor small molecule drug, which is being evaluated in phase 3 clinical trials for the treatment of nerve agent induced brain injury.

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            May 12, 2025

                            Lead Product(s) : Bucillamine

                            Therapeutic Area : Neurology

                            Highest Development Status : Preclinical

                            Sponsor : DRDC

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Alchemab

                            United Kingdom arrow
                            Discovery Europe
                            Not Confirmed

                            Alchemab

                            United Kingdom arrow
                            Discovery Europe
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : ATLX-1282

                            Therapeutic Area : Neurology

                            Study Phase : Preclinical

                            Sponsor : Eli Lilly

                            Deal Size : $415.0 million

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Alchemab Inks $415M Licensing Deal with Eli Lilly for ATLX-1282 Development

                            Details : Under the licensing agreement, Alchemab will be taking the programme through early Phase 1 clinical trials of ATLX-1282 after which Lilly will lead all further development and commercialisation.

                            Product Name : ATLX-1282

                            Product Type : Antibody

                            Upfront Cash : Undisclosed

                            May 06, 2025

                            Lead Product(s) : ATLX-1282

                            Therapeutic Area : Neurology

                            Highest Development Status : Preclinical

                            Sponsor : Eli Lilly

                            Deal Size : $415.0 million

                            Deal Type : Licensing Agreement

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                            08

                            Scribe Therapeutics

                            U.S.A arrow
                            Discovery Europe
                            Not Confirmed

                            Scribe Therapeutics

                            U.S.A arrow
                            Discovery Europe
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Neurology

                            Study Phase : Preclinical

                            Sponsor : Prevail Therapeutics

                            Deal Size : $1575.0 million

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Scribe Hits Milestone with Prevail, Will Present AAV Tech at ASGCT

                            Details : Scribe and Prevail’s collaboration will advance in vivo therapeutics for neurological and neuromuscular diseases using Scribe’s CRISPR technology.

                            Product Name : Undisclosed

                            Product Type : Cell and Gene therapy

                            Upfront Cash : $75.0 million

                            April 28, 2025

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Neurology

                            Highest Development Status : Preclinical

                            Sponsor : Prevail Therapeutics

                            Deal Size : $1575.0 million

                            Deal Type : Collaboration

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                            09

                            Capsida

                            U.S.A arrow
                            Discovery Europe
                            Not Confirmed

                            Capsida

                            U.S.A arrow
                            Discovery Europe
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
                            Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.

                            Lead Product(s) : CAP-003

                            Therapeutic Area : Neurology

                            Study Phase : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Capsida Presents Best-in-Class CAP-003 Data in Parkinson’s Disease with GBA Mutations

                            Details : CAP-003, enabled by one of Capsida's proprietary engineered capsids and cargo, demonstrates best-in-class potential to effectively and safely treat parkinson's disease associated with GBA mutations.

                            Product Name : CAP-003

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Inapplicable

                            April 03, 2025

                            Lead Product(s) : CAP-003

                            Therapeutic Area : Neurology

                            Highest Development Status : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Hoth Therapeutics

                            U.S.A arrow
                            Discovery Europe
                            Not Confirmed

                            Hoth Therapeutics

                            U.S.A arrow
                            Discovery Europe
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
                            Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.

                            Lead Product(s) : HT-ALZ

                            Therapeutic Area : Neurology

                            Study Phase : Preclinical

                            Sponsor : Washington University School of Medicine

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Hoth, WashU Advance Alzheimer's Program with NK-1 Antagonist HT-ALZ

                            Details : The collaboration aims to advance the clinical development of HT-ALZ, which is being evaluated for the treatment of Alzheimer's disease.

                            Product Name : HT-ALZ

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            April 02, 2025

                            Lead Product(s) : HT-ALZ

                            Therapeutic Area : Neurology

                            Highest Development Status : Preclinical

                            Sponsor : Washington University School of Medicine

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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