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Find Clinical Drug Pipeline Developments & Deals by NeuBase Therapeutics

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          American Thoracic Society
                          Not Confirmed
                          American Thoracic Society
                          Not Confirmed

                          Details : Under the terms of the agreement, NeuBase and the Healthcare Company will collaborate on the evaluation of drug candidates for three undisclosed indications.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          October 21, 2022

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Discovery

                          Sponsor : Undisclosed

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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                          02

                          American Thoracic Society
                          Not Confirmed
                          American Thoracic Society
                          Not Confirmed

                          Details : A single intravenous dose of NeuBase’s Myotonic Dystrophy Type 1 (DM1) development candidate, NT-0231.F, potently rescues splicing, restores chloride channel (Clcn1) function, and durably reverses myotonia in the HSALR model.

                          Product Name : NT-0231.F

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          March 13, 2022

                          Lead Product(s) : NT-0231.F

                          Therapeutic Area : Neurology

                          Highest Development Status : Preclinical

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          American Thoracic Society
                          Not Confirmed
                          American Thoracic Society
                          Not Confirmed

                          Details : NeuBase’s drug candidate for the NT-0200 program is designed to engage with the toxic RNA hairpin structure and release the splicing proteins to restore normal RNA splicing and downstream protein production.

                          Product Name : NT0200

                          Product Type : Oligonucleotide

                          Upfront Cash : Inapplicable

                          February 28, 2022

                          Lead Product(s) : NT0200

                          Therapeutic Area : Neurology

                          Highest Development Status : Preclinical

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          American Thoracic Society
                          Not Confirmed
                          American Thoracic Society
                          Not Confirmed

                          Details : NeuBase recently presented data demonstrated systemic administration of NT-0231.F in HSALR model achieves clinically relevant molecular and functional rescue, including rescue of spliceopathy, resolution of nuclear aggregates, and reversal of myotonia.

                          Product Name : NT-0231.F

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          February 05, 2022

                          Lead Product(s) : NT-0231.F

                          Therapeutic Area : Neurology

                          Highest Development Status : Preclinical

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          American Thoracic Society
                          Not Confirmed
                          American Thoracic Society
                          Not Confirmed

                          Details : The NT0200 program is a PATrOL™-enabled therapeutic program being developed to target the mutant expansion in the DM1 disease mRNA. Data presented today at NeuBase’s R&D Day show functional rescue of myotonic dystrophy type 1 phenotype in vivo after ...

                          Product Name : NT0200

                          Product Type : Oligonucleotide

                          Upfront Cash : Inapplicable

                          August 06, 2021

                          Lead Product(s) : NT0200

                          Therapeutic Area : Neurology

                          Highest Development Status : Preclinical

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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