Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Undisclosed
Therapeutic Area : Genetic Disease
Study Phase : Discovery
Sponsor : Undisclosed
Deal Size : Undisclosed
Deal Type : Agreement
NeuBase Therapeutics Announces Gene Editing Research Agreement with Global Healthcare Company
Details : Under the terms of the agreement, NeuBase and the Healthcare Company will collaborate on the evaluation of drug candidates for three undisclosed indications.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
October 21, 2022
Lead Product(s) : Undisclosed
Therapeutic Area : Genetic Disease
Highest Development Status : Discovery
Sponsor : Undisclosed
Deal Size : Undisclosed
Deal Type : Agreement
Lead Product(s) : NT-0231.F
Therapeutic Area : Neurology
Study Phase : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : A single intravenous dose of NeuBase’s Myotonic Dystrophy Type 1 (DM1) development candidate, NT-0231.F, potently rescues splicing, restores chloride channel (Clcn1) function, and durably reverses myotonia in the HSALR model.
Product Name : NT-0231.F
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
March 13, 2022
Lead Product(s) : NT-0231.F
Therapeutic Area : Neurology
Highest Development Status : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : NT0200
Therapeutic Area : Neurology
Study Phase : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : NeuBase’s drug candidate for the NT-0200 program is designed to engage with the toxic RNA hairpin structure and release the splicing proteins to restore normal RNA splicing and downstream protein production.
Product Name : NT0200
Product Type : Oligonucleotide
Upfront Cash : Inapplicable
February 28, 2022
Lead Product(s) : NT0200
Therapeutic Area : Neurology
Highest Development Status : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : NT-0231.F
Therapeutic Area : Neurology
Study Phase : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : NeuBase recently presented data demonstrated systemic administration of NT-0231.F in HSALR model achieves clinically relevant molecular and functional rescue, including rescue of spliceopathy, resolution of nuclear aggregates, and reversal of myotonia.
Product Name : NT-0231.F
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
February 05, 2022
Lead Product(s) : NT-0231.F
Therapeutic Area : Neurology
Highest Development Status : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : NT0200
Therapeutic Area : Neurology
Study Phase : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : The NT0200 program is a PATrOL™-enabled therapeutic program being developed to target the mutant expansion in the DM1 disease mRNA. Data presented today at NeuBase’s R&D Day show functional rescue of myotonic dystrophy type 1 phenotype in vivo after ...
Product Name : NT0200
Product Type : Oligonucleotide
Upfront Cash : Inapplicable
August 06, 2021
Lead Product(s) : NT0200
Therapeutic Area : Neurology
Highest Development Status : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable