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    [{"orgOrder":0,"company":"NeoTX Therapeutics","sponsor":"Translational Drug Development","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"ISRAEL","productType":"Antibody-drug Conjugate","year":"2021","type":"Inapplicable","leadProduct":"Naptumomab Estafenatox","moa":"Trophoblast glycoprotein","graph1":"Oncology","graph2":"Phase II","graph3":"NeoTX Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Injection","sponsorNew":"NeoTX Therapeutics \/ Translational Drug Development","highestDevelopmentStatusID":"8","companyTruncated":"NeoTX Therapeutics \/ Translational Drug Development"},{"orgOrder":0,"company":"NeoTX Therapeutics","sponsor":"Translational Drug Development","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"ISRAEL","productType":"Antibody-drug Conjugate","year":"2022","type":"Inapplicable","leadProduct":"Docetaxel","moa":"||Trophoblast 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Therapeutics","highestDevelopmentStatusID":"7","companyTruncated":"NeoTX Therapeutics \/ NeoTX Therapeutics"},{"orgOrder":0,"company":"NeoTX Therapeutics","sponsor":"Undisclosed","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"ISRAEL","productType":"Antibody-drug Conjugate","year":"2020","type":"Series C Financing","leadProduct":"Durvalumab","moa":"||Trophoblast glycoprotein","graph1":"Oncology","graph2":"Phase I","graph3":"NeoTX Therapeutics","amount2":0.050000000000000003,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0.050000000000000003,"dosageForm":"Intravenous Injection","sponsorNew":"NeoTX Therapeutics \/ Undisclosed","highestDevelopmentStatusID":"6","companyTruncated":"NeoTX Therapeutics \/ Undisclosed"},{"orgOrder":0,"company":"NeoTX Therapeutics","sponsor":"Active Biotech","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"SWEDEN","productType":"Antibody-drug Conjugate","year":"2020","type":"Licensing Agreement","leadProduct":"Durvalumab","moa":"||Trophoblast glycoprotein","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"NeoTX Therapeutics","amount2":0.070000000000000007,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0.070000000000000007,"dosageForm":"Intravenous Injection","sponsorNew":"NeoTX Therapeutics \/ NeoTX Therapeutics","highestDevelopmentStatusID":"7","companyTruncated":"NeoTX Therapeutics \/ NeoTX Therapeutics"},{"orgOrder":0,"company":"NeoTX Therapeutics","sponsor":"Active Biotech","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"SWEDEN","productType":"Antibody-drug Conjugate","year":"2021","type":"Inapplicable","leadProduct":"Durvalumab","moa":"||Trophoblast glycoprotein","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"NeoTX Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Injection","sponsorNew":"NeoTX Therapeutics \/ NeoTX Therapeutics","highestDevelopmentStatusID":"7","companyTruncated":"NeoTX Therapeutics \/ NeoTX Therapeutics"},{"orgOrder":0,"company":"NeoTX Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"ISRAEL","productType":"Antibody-drug Conjugate","year":"2021","type":"Inapplicable","leadProduct":"Durvalumab","moa":"||Trophoblast glycoprotein","graph1":"Oncology","graph2":"Phase I","graph3":"NeoTX Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Injection","sponsorNew":"NeoTX Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"NeoTX Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"NeoTX Therapeutics","sponsor":"NeoTX Therapeutics","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Antibody-drug Conjugate","year":"2023","type":"Inapplicable","leadProduct":"Naptumomab Estafenatox","moa":"Trophoblast glycoprotein","graph1":"Oncology","graph2":"Phase I","graph3":"NeoTX Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"NeoTX Therapeutics \/ NeoTX Therapeutics","highestDevelopmentStatusID":"6","companyTruncated":"NeoTX Therapeutics \/ NeoTX Therapeutics"}]

    Find Clinical Drug Pipeline Developments & Deals by NeoTX Therapeutics

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                            01

                            NeoTX Therapeutics

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                            Lead Product(s) : Naptumomab Estafenatox

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Recipient : Weill Medical College of Cornell University

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Naptumomab Estafenatox in Combination With Pembrolizumab Preceded by Obinutuzumab in Patients With Urothelial ...

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Antibody-drug Conjugate

                            Upfront Cash : Inapplicable

                            June 08, 2023

                            Lead Product(s) : Naptumomab Estafenatox

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Recipient : Weill Medical College of Cornell University

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            NeoTX Therapeutics

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                            NeoTX Therapeutics

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                            Lead Product(s) : Naptumomab Estafenatox,Docetaxel,Obinutuzumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Translational Drug Development

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Neotx Announces Successful First Stage Completion of Its Phase 2a Clinical Trial of Naptumomab Estafenatox (Na...

                            Details : Naptumomab estafenatox (NAP; ABR-217620) is a recombinant fusion protein consisting of a chimeric staphylococcal enterotoxin A/E (SEA/SEE) superantigen with several additional substitutions that is linked to a Fab moiety recognizing a tumor-associated gl...

                            Product Name : Undisclosed

                            Product Type : Antibody-drug Conjugate

                            Upfront Cash : Inapplicable

                            January 06, 2022

                            Lead Product(s) : Naptumomab Estafenatox,Docetaxel,Obinutuzumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Translational Drug Development

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            NeoTX Therapeutics

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                            Lead Product(s) : Naptumomab Estafenatox,Durvalumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Recipient : Active Biotech

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Data on Naptumomab Estafenatox Enhancing CAR-T Cells Potency Presented by Active Biotech’s Partner NeoTX at ...

                            Details : Naptumomab estafenatox (NAP) is a cell therapy candidate, currently in Phase I. It is in clinical development for advanced solid tumors utilizing its proprietary Tumor Targeted Superantigen platform.

                            Product Name : Undisclosed

                            Product Type : Antibody-drug Conjugate

                            Upfront Cash : Inapplicable

                            November 30, 2021

                            Lead Product(s) : Naptumomab Estafenatox,Durvalumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Recipient : Active Biotech

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            NeoTX Therapeutics

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                            Lead Product(s) : Naptumomab Estafenatox

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Translational Drug Development

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            NAP in Combination With Docetaxel Following Obinutuzumab Pretreatment in Subjects With Checkpoint Inhibitor Pr...

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Antibody-drug Conjugate

                            Upfront Cash : Inapplicable

                            May 11, 2021

                            Lead Product(s) : Naptumomab Estafenatox

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Translational Drug Development

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            NeoTX Therapeutics

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                            Lead Product(s) : Naptumomab Estafenatox,Durvalumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Recipient : Active Biotech

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Active Biotech Provides Status Update of its Clinical Naptumomab Project

                            Details : The study was amended to also include assessment of pre-treatment with obinutuzumab to assess its effect on anti-drug antibodies (ADAs) to naptumomab.

                            Product Name : Undisclosed

                            Product Type : Antibody-drug Conjugate

                            Upfront Cash : Inapplicable

                            May 07, 2021

                            Lead Product(s) : Naptumomab Estafenatox,Durvalumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Recipient : Active Biotech

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            NeoTX Therapeutics

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                            NeoTX Therapeutics

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                            Lead Product(s) : Naptumomab Estafenatox,Durvalumab

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            US FDA Clears NeoTX’s IND Application for Phase 2 Trial of Naptumomab Estafenatox to Treat Solid Tumors

                            Details : Naptumomab Estafenatox, the company’s lead TTS molecule, binds a genetically engineered bacterial determinant to the tumor surface while simultaneously activating and expanding tumor specific immune cells.

                            Product Name : Undisclosed

                            Product Type : Antibody-drug Conjugate

                            Upfront Cash : Inapplicable

                            April 19, 2021

                            Lead Product(s) : Naptumomab Estafenatox,Durvalumab

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            NeoTX Therapeutics

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                            NeoTX Therapeutics

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                            Lead Product(s) : Naptumomab Estafenatox,Durvalumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Recipient : Active Biotech

                            Deal Size : $71.0 million

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Active Biotech Receive Milestone Payment From Neotx

                            Details : In 2016, Active Biotech and NeoTX entered into a partnership for the development and commercialization of naptumomab in cancer indications.

                            Product Name : Undisclosed

                            Product Type : Antibody-drug Conjugate

                            Upfront Cash : Undisclosed

                            November 12, 2020

                            Lead Product(s) : Naptumomab Estafenatox,Durvalumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Recipient : Active Biotech

                            Deal Size : $71.0 million

                            Deal Type : Licensing Agreement

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                            08

                            NeoTX Therapeutics

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                            Lead Product(s) : Naptumomab Estafenatox,Durvalumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : $45.0 million

                            Deal Type : Series C Financing

                            DEALS_DEV arrow-down

                            Israeli biotech NeoTX lands $45M series C for combo I-O cancer trials

                            Details : The company plans to complete the dose escalation phase of the Phase 1b trial of naptumomab estafenatox in combination with durvalumab and continue to develop our patented STR platform.

                            Product Name : Undisclosed

                            Product Type : Antibody-drug Conjugate

                            Upfront Cash : Undisclosed

                            February 19, 2020

                            Lead Product(s) : Naptumomab Estafenatox,Durvalumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : $45.0 million

                            Deal Type : Series C Financing

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                            09

                            NeoTX Therapeutics

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                            Lead Product(s) : Naptumomab Estafenatox

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : AstraZeneca

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Naptumomab Estafenatox in Combination with Durvalumab in Subjects with Selected Advanced or Metastatic Solid T...

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Antibody-drug Conjugate

                            Upfront Cash : Inapplicable

                            June 12, 2019

                            Lead Product(s) : Naptumomab Estafenatox

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : AstraZeneca

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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