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                            National Institute on Drug Abuse

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                            Lead Product(s) : OMS527

                            Therapeutic Area : Psychiatry/Psychology

                            Study Phase : Phase I

                            Recipient : Omeros

                            Deal Size : $4.0 million

                            Deal Type : Funding

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                            Omeros Secures $4M from NIDA for OMS527 To Treat Cocaine Use Disorder

                            Details : The funding aims to support the OMS527 is an orally bioavailable, small molecule antagonist of PDE7. It is being evaluated to treat Cocaine Use Disorder.

                            Product Name : Undisclosed

                            Product Type : Oligonucleotide

                            Upfront Cash : Undisclosed

                            March 13, 2025

                            Lead Product(s) : OMS527

                            Therapeutic Area : Psychiatry/Psychology

                            Highest Development Status : Phase I

                            Recipient : Omeros

                            Deal Size : $4.0 million

                            Deal Type : Funding

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                            National Institutes of Health

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                            Lead Product(s) : FZ002

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : IND Enabling

                            Recipient : Fzata

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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                            C. difficile Clinical Trial Agreement for Fzata's FZ002

                            Details : The agreement aims to sponsor a Phase 1 clinical trial of FZ002, a live yeast genetically modified to express a tetraspecific anti-toxin for C. difficile treatment.

                            Product Name : Undisclosed

                            Product Type : Microorganism

                            Upfront Cash : Undisclosed

                            March 11, 2025

                            Lead Product(s) : FZ002

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : IND Enabling

                            Recipient : Fzata

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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                            03

                            National Institute on Drug Abuse

                            U.S.A arrow
                            iPHEX India
                            Not Confirmed

                            National Institute on Drug Abuse

                            U.S.A arrow
                            iPHEX India
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Psilocybine

                            Therapeutic Area : Psychiatry/Psychology

                            Study Phase : Phase II

                            Recipient : NYU Langone Health

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Psilocybin for Opioid Use Disorder (OUD)

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            January 28, 2025

                            Lead Product(s) : Psilocybine

                            Therapeutic Area : Psychiatry/Psychology

                            Highest Development Status : Phase II

                            Recipient : NYU Langone Health

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            National Institute on Aging

                            U.S.A arrow
                            iPHEX India
                            Not Confirmed

                            National Institute on Aging

                            U.S.A arrow
                            iPHEX India
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : AKV9

                            Therapeutic Area : Neurology

                            Study Phase : IND Enabling

                            Recipient : AKAVA Therapeutics

                            Deal Size : $7.3 million

                            Deal Type : Funding

                            DEALS_DEV arrow-down

                            Akava Therapeutics Celebrates $7.3M Grant to Study AKV9 in Neurodegeneration

                            Details : The funding will support Akava’s lead compound, NU-9 (AKV9). It is being evaluated for the treatment of Alzheimer’s disease and frontotemporal dementia.

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            December 17, 2024

                            Lead Product(s) : AKV9

                            Therapeutic Area : Neurology

                            Highest Development Status : IND Enabling

                            Recipient : AKAVA Therapeutics

                            Deal Size : $7.3 million

                            Deal Type : Funding

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                            05

                            The Division of Cancer Treatment and Diagnosis

                            U.S.A arrow
                            iPHEX India
                            Not Confirmed

                            The Division of Cancer Treatment and Diagnosis

                            U.S.A arrow
                            iPHEX India
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Camonsertib

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Recipient : Repare Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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                            Repare Partners with US NCI To Advance Camonsertib Development

                            Details : The agreement aims to advance the development of camonsertib, a potential best-in-class oral small molecule ATR inhibitor, currently in Phase 1/2 in patients with ATM-altered tumors.

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            December 11, 2024

                            Lead Product(s) : Camonsertib

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Recipient : Repare Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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                            06

                            National Institute of Allergy and Infectious Diseases

                            U.S.A arrow
                            iPHEX India
                            Not Confirmed

                            National Institute of Allergy and Infectious Diseases

                            U.S.A arrow
                            iPHEX India
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Pramipexole Dihydrochloride

                            Therapeutic Area : Psychiatry/Psychology

                            Study Phase : Phase II

                            Sponsor : Cipla

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Pramipexole Versus Escitalopram to Treat Major Depressive Disorder (MDD) and Comorbid MDD With Mild Neurocogni...

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            November 26, 2024

                            Lead Product(s) : Pramipexole Dihydrochloride

                            Therapeutic Area : Psychiatry/Psychology

                            Highest Development Status : Phase II

                            Sponsor : Cipla

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            National Institute of Allergy and Infectious Diseases

                            U.S.A arrow
                            iPHEX India
                            Not Confirmed

                            National Institute of Allergy and Infectious Diseases

                            U.S.A arrow
                            iPHEX India
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Ledaborbactam Etzadroxil

                            Therapeutic Area : Undisclosed

                            Study Phase : Phase I

                            Recipient : VenatoRx Pharmaceuticals

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Plasma and Intrapulmonary Pharmacokinetics of Ceftibuten and Ledaborbactam in Healthy Male and Female Particip...

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            October 30, 2024

                            Lead Product(s) : Ledaborbactam Etzadroxil

                            Therapeutic Area : Undisclosed

                            Highest Development Status : Phase I

                            Recipient : VenatoRx Pharmaceuticals

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            National Institute of Allergy and Infectious Diseases

                            U.S.A arrow
                            iPHEX India
                            Not Confirmed

                            National Institute of Allergy and Infectious Diseases

                            U.S.A arrow
                            iPHEX India
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Babesia Vaccine

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Discovery

                            Recipient : ATCC (American Type Culture Collection)

                            Deal Size : $0.1 million

                            Deal Type : Funding

                            DEALS_DEV arrow-down

                            ATCC Announces Subaward to Advance Research for Tickborne Diseases and Vaccine Development

                            Details : The proceeds will be used to advance babesiosis and tickborne disease research by addressing an underappreciated and understudied area of babesia biology and pathogenesis.

                            Product Name : Undisclosed

                            Product Type : Vaccine

                            Upfront Cash : Undisclosed

                            October 30, 2024

                            Lead Product(s) : Babesia Vaccine

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Discovery

                            Recipient : ATCC (American Type Culture Collection)

                            Deal Size : $0.1 million

                            Deal Type : Funding

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                            09

                            National Institutes of Health

                            U.S.A arrow
                            iPHEX India
                            Not Confirmed

                            National Institutes of Health

                            U.S.A arrow
                            iPHEX India
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Neurology

                            Study Phase : Preclinical

                            Recipient : EydisBio

                            Deal Size : $0.5 million

                            Deal Type : Funding

                            DEALS_DEV arrow-down

                            EydisBio Wins $0.5M Grant for Alzheimer’s TAK1 Inhibitor Program

                            Details : The grant will support EydisBio's pioneering research into new therapeutic approaches for Alzheimer's disease, focusing on the inhibition of TGFβ-activated protein kinase 1 (TAK1).

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Undisclosed

                            October 23, 2024

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Neurology

                            Highest Development Status : Preclinical

                            Recipient : EydisBio

                            Deal Size : $0.5 million

                            Deal Type : Funding

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                            10

                            National Institute on Drug Abuse

                            U.S.A arrow
                            iPHEX India
                            Not Confirmed

                            National Institute on Drug Abuse

                            U.S.A arrow
                            iPHEX India
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : SBP-9330

                            Therapeutic Area : Psychiatry/Psychology

                            Study Phase : Phase I

                            Recipient : Camino Pharma

                            Deal Size : $9.0 million

                            Deal Type : Funding

                            DEALS_DEV arrow-down

                            $9 Million NIH Grant Advances Drug to Treat Nicotine Addiction

                            Details : The net proceeds will fund longer toxicology studies and manufacturing of SBP-9330, a small molecule targeting mGlu2 receptor, to support planned Phase 2 trials for nicotine cessation.

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            June 02, 2024

                            Lead Product(s) : SBP-9330

                            Therapeutic Area : Psychiatry/Psychology

                            Highest Development Status : Phase I

                            Recipient : Camino Pharma

                            Deal Size : $9.0 million

                            Deal Type : Funding

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