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Diseases","country":"U.S.A","productType":"Undisclosed","year":"2024","type":"Funding","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Infections and Infectious Diseases","graph2":"Discovery","graph3":"National Institutes of Health","amount2":0,"highestDevelopmentShortName":"Discovery","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"National Institutes of Health \/ National Institutes of Health","highestDevelopmentStatusID":"2","companyTruncated":"National Institutes of Health \/ National Institutes of Health"},{"orgOrder":0,"company":"National Institutes of Health","sponsor":"Avexegen Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Gastroenterology","country":"U.S.A","productType":"Undisclosed","year":"2021","type":"Funding","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Gastroenterology","graph2":"Undisclosed","graph3":"National Institutes of Health","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Gastroenterology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"National Institutes of Health \/ National Institutes of Health","highestDevelopmentStatusID":"1","companyTruncated":"National Institutes of Health \/ National Institutes of Health"},{"orgOrder":0,"company":"National Institutes of Health","sponsor":"Connectyx","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Undisclosed","year":"2020","type":"Licensing Agreement","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Oncology","graph2":"Preclinical","graph3":"National Institutes of Health","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"National Institutes of Health \/ Connectyx","highestDevelopmentStatusID":"4","companyTruncated":"National Institutes of Health \/ Connectyx"},{"orgOrder":0,"company":"National Institutes of Health","sponsor":"Orlance","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Undisclosed","year":"2023","type":"Funding","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Infections and Infectious Diseases","graph2":"Preclinical","graph3":"National Institutes of Health","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"National Institutes of Health \/ National Institutes of Health","highestDevelopmentStatusID":"4","companyTruncated":"National Institutes of Health \/ National Institutes of Health"},{"orgOrder":0,"company":"National Cancer Institute","sponsor":"Eureka Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Undisclosed","year":"2023","type":"Licensing Agreement","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Oncology","graph2":"Preclinical","graph3":"National Cancer Institute","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"National Cancer Institute \/ Eureka Therapeutics","highestDevelopmentStatusID":"4","companyTruncated":"National Cancer Institute \/ Eureka Therapeutics"},{"orgOrder":0,"company":"National Institute on Drug Abuse","sponsor":"Copernicus Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Psychiatry\/Psychology","country":"U.S.A","productType":"Undisclosed","year":"2022","type":"Funding","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Psychiatry\/Psychology","graph2":"Preclinical","graph3":"National Institute on Drug Abuse","amount2":0.02,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Psychiatry","amount2New":0.02,"dosageForm":"Undisclosed","sponsorNew":"National Institute on Drug Abuse \/ National Institute on Drug Abuse","highestDevelopmentStatusID":"4","companyTruncated":"National Institute on Drug Abuse \/ National Institute on Drug Abuse"},{"orgOrder":0,"company":"National Institutes of Health","sponsor":"SQZ Biotechnologies","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"U.S.A","productType":"Undisclosed","year":"2022","type":"Funding","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Neurology","graph2":"Preclinical","graph3":"National Institutes of Health","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"National Institutes of Health \/ National Institutes of Health","highestDevelopmentStatusID":"4","companyTruncated":"National Institutes of Health \/ National Institutes of Health"},{"orgOrder":0,"company":"National Institutes of Health","sponsor":"Q-State Biosciences","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"U.S.A","productType":"Undisclosed","year":"2021","type":"Funding","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Neurology","graph2":"Discovery","graph3":"National Institutes of Health","amount2":0,"highestDevelopmentShortName":"Discovery","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"National Institutes of Health \/ National Institutes of Health","highestDevelopmentStatusID":"2","companyTruncated":"National Institutes of Health \/ National Institutes of Health"},{"orgOrder":0,"company":"National Institutes of Health","sponsor":"1910 Genetics","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"U.S.A","productType":"Undisclosed","year":"2021","type":"Funding","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Neurology","graph2":"Discovery","graph3":"National Institutes of Health","amount2":0,"highestDevelopmentShortName":"Discovery","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"National Institutes of Health \/ National Institutes of Health","highestDevelopmentStatusID":"2","companyTruncated":"National Institutes of Health \/ National Institutes of Health"},{"orgOrder":0,"company":"National Institutes of Health","sponsor":"Altesa Biosciences","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Undisclosed","year":"2022","type":"Funding","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Infections and Infectious Diseases","graph2":"Discovery","graph3":"National Institutes of Health","amount2":0.050000000000000003,"highestDevelopmentShortName":"Discovery","therapeuticAreaShortName":"Infectious Diseases","amount2New":0.050000000000000003,"dosageForm":"Undisclosed","sponsorNew":"National Institutes of Health \/ National Institutes of Health","highestDevelopmentStatusID":"2","companyTruncated":"National Institutes of Health \/ National Institutes of Health"},{"orgOrder":0,"company":"National Eye Institute","sponsor":"Synedgen","pharmaFlowCategory":"D","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Undisclosed","year":"2020","type":"Funding","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Ophthalmology","graph2":"Discovery","graph3":"National Eye Institute","amount2":0,"highestDevelopmentShortName":"Discovery","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"National Eye Institute \/ National Eye Institute","highestDevelopmentStatusID":"2","companyTruncated":"National Eye Institute \/ National Eye Institute"},{"orgOrder":0,"company":"National Institutes of Health","sponsor":"Adamis Pharmaceuticals","pharmaFlowCategory":"D","therapeuticArea":"Psychiatry\/Psychology","country":"U.S.A","productType":"Undisclosed","year":"2023","type":"Funding","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Psychiatry\/Psychology","graph2":"Undisclosed","graph3":"National Institutes of Health","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Psychiatry","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"National Institutes of Health \/ National Institutes of Health","highestDevelopmentStatusID":"1","companyTruncated":"National Institutes of Health \/ National Institutes of Health"},{"orgOrder":0,"company":"National Cancer Institute","sponsor":"Endure Bio","pharmaFlowCategory":"D","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Microorganism","year":"2025","type":"Funding","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Genetic Disease","graph2":"Preclinical","graph3":"National Cancer Institute","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"National Cancer Institute \/ National Cancer Institute","highestDevelopmentStatusID":"4","companyTruncated":"National Cancer Institute \/ National Cancer Institute"},{"orgOrder":0,"company":"National Institutes of Health","sponsor":"Neucore Bio","pharmaFlowCategory":"D","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Oligonucleotide","year":"2025","type":"Funding","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Genetic Disease","graph2":"Preclinical","graph3":"National Institutes of Health","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"National Institutes of Health \/ National Institutes of Health","highestDevelopmentStatusID":"4","companyTruncated":"National Institutes of Health \/ National Institutes of Health"}]

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                            01

                            National Institute of Allergy and Infectious Diseases

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                            National Institute of Allergy and Infectious Diseases

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                            Lead Product(s) : R21

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase II

                            Recipient : Serum Institute of India

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Pfs230D1 + R21 in Matrix-M1 in African School Children and Adults

                            Details : R21 is a Vaccine drug candidate, which is currently being evaluated in Phase II clinical studies for the treatment of Malaria.

                            Product Name : Undisclosed

                            Product Type : Vaccine

                            Upfront Cash : Inapplicable

                            August 29, 2025

                            Lead Product(s) : R21

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase II

                            Recipient : Serum Institute of India

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            National Institute of Allergy and Infectious Diseases

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                            Organic Process R&D
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                            National Institute of Allergy and Infectious Diseases

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                            Organic Process R&D
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                            Lead Product(s) : Glecaprevir

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase I/ Phase II

                            Sponsor : Gansu Provincial Maternal and Child Health Care Hospital | National Institute of Mental Health | AbbVie Inc

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Glecaprevir/Pibrentasvir PK and Safety In Pregnant Women with HCV ± HIV

                            Details : Glecaprevir is a Other Small Molecule drug candidate, which is currently being evaluated in Phase I/ Phase II clinical studies for the treatment of Hepatitis C.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            June 27, 2025

                            Lead Product(s) : Glecaprevir

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Gansu Provincial Maternal and Child Health Care Hospital | National Institute of Mental Health | AbbVie Inc

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            National Institute of Allergy and Infectious Diseases

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                            Organic Process R&D
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                            National Institute of Allergy and Infectious Diseases

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                            Organic Process R&D
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                            Lead Product(s) : Tezepelumab

                            Therapeutic Area : Immunology

                            Study Phase : Phase II

                            Sponsor : Immune Tolerance Network | PPD | Rho, Inc

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Efficacy of Tezepelumab in Peanut Oral Immunotherapy

                            Details : Tezepelumab is a Antibody drug candidate, which is currently being evaluated in Phase II clinical studies for the treatment of Peanut Hypersensitivity.

                            Product Name : Undisclosed

                            Product Type : Antibody, Unconjugated

                            Upfront Cash : Inapplicable

                            June 11, 2025

                            Lead Product(s) : Tezepelumab

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase II

                            Sponsor : Immune Tolerance Network | PPD | Rho, Inc

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            National Institutes of Health

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                            Organic Process R&D
                            Not Confirmed

                            National Institutes of Health

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                            Organic Process R&D
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                            Lead Product(s) : AVR-48

                            Therapeutic Area : Undisclosed

                            Study Phase : Phase I

                            Recipient : AyuVis Research

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Single Ascending Dose and Multiple Ascending Dose Study of AVR-48

                            Details : AVR-48 is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of undefined medical condition.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            February 26, 2025

                            Lead Product(s) : AVR-48

                            Therapeutic Area : Undisclosed

                            Highest Development Status : Phase I

                            Recipient : AyuVis Research

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            National Institute of Allergy and Infectious Diseases

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                            Organic Process R&D
                            Not Confirmed

                            National Institute of Allergy and Infectious Diseases

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                            Organic Process R&D
                            Not Confirmed
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                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Lopinavir,Ritonavir

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Recipient : Daré Bioscience

                            Deal Size : $2.0 million

                            Deal Type : Funding

                            DEALS_DEV arrow-down

                            Daré Bioscience Gets NIH Award for DARE-HPV Development Support

                            Details : The funding aims to fund the clinical development activities of DARE-HPV (lopinavir and ritonavir), which is being evaluated for the treatment of HPV-related cervical cancer.

                            Product Name : DARE-HPV

                            Product Type : Miscellaneous

                            Upfront Cash : Undisclosed

                            February 06, 2025

                            Lead Product(s) : Lopinavir,Ritonavir

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Recipient : Daré Bioscience

                            Deal Size : $2.0 million

                            Deal Type : Funding

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                            06

                            National Institutes of Health

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                            Organic Process R&D
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                            National Institutes of Health

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                            Organic Process R&D
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                            Lead Product(s) : ALX1

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase I

                            Recipient : Vast Therapeutics

                            Deal Size : $2.0 million

                            Deal Type : Funding

                            DEALS_DEV arrow-down

                            Vast Awarded $2 Million Grant to Combat Deadly Respiratory Bacteria

                            Details : The Funds from NIH will advance ALX1 as a potential treatment in Cystic Fibrosis and other chronic lung diseases.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Undisclosed

                            January 21, 2025

                            Lead Product(s) : ALX1

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase I

                            Recipient : Vast Therapeutics

                            Deal Size : $2.0 million

                            Deal Type : Funding

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                            07

                            National Institutes of Health

                            U.S.A arrow
                            Organic Process R&D
                            Not Confirmed

                            National Institutes of Health

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                            Organic Process R&D
                            Not Confirmed
                            • fda
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                            Lead Product(s) : SBS-226

                            Therapeutic Area : Psychiatry/Psychology

                            Study Phase : Preclinical

                            Recipient : Sparian Biosciences

                            Deal Size : $19.5 million

                            Deal Type : Funding

                            DEALS_DEV arrow-down

                            Sparian Wins $19.5M NIH Grant for Opiate Use Disorder Drug Development

                            Details : The proceeds will be used to fund development of SBS-226, a first-in-class dual MOR partial agonist and DOR full antagonist, from IND submission through Phase 1 clinical development.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Undisclosed

                            November 14, 2024

                            Lead Product(s) : SBS-226

                            Therapeutic Area : Psychiatry/Psychology

                            Highest Development Status : Preclinical

                            Recipient : Sparian Biosciences

                            Deal Size : $19.5 million

                            Deal Type : Funding

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                            08

                            National Institute on Drug Abuse

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                            Organic Process R&D
                            Not Confirmed

                            National Institute on Drug Abuse

                            U.S.A arrow
                            Organic Process R&D
                            Not Confirmed
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                            Lead Product(s) : Psilocybine

                            Therapeutic Area : Psychiatry/Psychology

                            Study Phase : IND Enabling

                            Recipient : NYU Langone Health

                            Deal Size : $15.0 million

                            Deal Type : Funding

                            DEALS_DEV arrow-down

                            $15M NIDA Grant Funds Psilocybin Study in Opioid Use Disorder

                            Details : The funding will support the first clinical trial to evaluate psilocybin's efficacy as a treatment for Opioid Use Disorder (OUD).

                            Product Name : Undisclosed

                            Product Type : Controlled Substance

                            Upfront Cash : Undisclosed

                            October 31, 2024

                            Lead Product(s) : Psilocybine

                            Therapeutic Area : Psychiatry/Psychology

                            Highest Development Status : IND Enabling

                            Recipient : NYU Langone Health

                            Deal Size : $15.0 million

                            Deal Type : Funding

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                            09

                            National Institute of Allergy and Infectious Diseases

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                            Organic Process R&D
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                            National Institute of Allergy and Infectious Diseases

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                            Organic Process R&D
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                            Lead Product(s) : Babesia Vaccine

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Discovery

                            Recipient : ATCC (American Type Culture Collection)

                            Deal Size : $0.1 million

                            Deal Type : Funding

                            DEALS_DEV arrow-down

                            ATCC Announces Subaward to Advance Research for Tickborne Diseases and Vaccine Development

                            Details : The proceeds will be used to advance babesiosis and tickborne disease research by addressing an underappreciated and understudied area of babesia biology and pathogenesis.

                            Product Name : Undisclosed

                            Product Type : Vaccine

                            Upfront Cash : Undisclosed

                            October 30, 2024

                            Lead Product(s) : Babesia Vaccine

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Discovery

                            Recipient : ATCC (American Type Culture Collection)

                            Deal Size : $0.1 million

                            Deal Type : Funding

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                            10

                            National Institute of Allergy and Infectious Diseases

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                            Organic Process R&D
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                            National Institute of Allergy and Infectious Diseases

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                            Organic Process R&D
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                            Lead Product(s) : PepGNP-COVID19

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase I/ Phase II

                            Recipient : Gylden Pharma

                            Deal Size : Undisclosed

                            Deal Type : Partnership

                            DEALS_DEV arrow-down

                            Emergex T Cell Vaccine Chosen for NIH/NIAID Betacoronavirus Trials

                            Details : NIAID will be conducting and sponsoring clinical trial to accelerate Emergex vaccine, CoronaTcP, designed to be broadly effective against Betacoronavirus infections, including SARS-CoV-1.

                            Product Name : CoronaTcP

                            Product Type : Vaccine

                            Upfront Cash : Undisclosed

                            October 02, 2024

                            Lead Product(s) : PepGNP-COVID19

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase I/ Phase II

                            Recipient : Gylden Pharma

                            Deal Size : Undisclosed

                            Deal Type : Partnership

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