Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Ruxotemitide,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase II
Recipient : Oslo University Hospital
Deal Size : Inapplicable
Deal Type : Inapplicable
NeoLIPA: Neoadjuvant LTX-315 in Combination with Pembrolizumab in Resectable Stage III/IV Melanoma
Details : Undisclosed
Product Name : Undisclosed
Product Type : Peptide
Upfront Cash : Inapplicable
October 21, 2024
Lead Product(s) : Ruxotemitide,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase II
Recipient : Oslo University Hospital
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Ruxotemitide,Undisclosed
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : The trial demonstrated that combination of LTX-315 and ACT is feasible and tolerable, and that CD4+ and CD8+ T cells can be expanded in vitro from STS that have been pretreated with the oncolytic molecule LTX-315.
Product Name : Undisclosed
Product Type : Peptide
Upfront Cash : Inapplicable
May 27, 2022
Lead Product(s) : Ruxotemitide,Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Ruxotemitide,Inapplicable
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Verrica Pharmaceuticals
Deal Size : $111.0 million
Deal Type : Licensing Agreement
Details : Verrica, has an exclusive license agreement with Lytix to develop and commercialize LTX-315 for skin cancer conditions. LTX-315 is a first-in-class oncolytic peptide derived from human lactoferrin, with potential lytic and immunostimulating activities.
Product Name : Undisclosed
Product Type : Peptide
Upfront Cash : Undisclosed
May 04, 2022
Lead Product(s) : Ruxotemitide,Inapplicable
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Verrica Pharmaceuticals
Deal Size : $111.0 million
Deal Type : Licensing Agreement
Lead Product(s) : Ruxotemitide,Tumor Infiltrating Lymphocyte
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lytix Biopharma to Present at the American Society of Clinical Oncology (ASCO) Annual Meeting
Details : LTX-315 is a potential first-in-class oncolytic molecule administered directly into a tumor to induce immunogenic cell death, which also has demonstrated positive tumor-specific immune cell responses in multi-indication Phase I/II oncology trials.
Product Name : Undisclosed
Product Type : Peptide
Upfront Cash : Inapplicable
April 28, 2022
Lead Product(s) : Ruxotemitide,Tumor Infiltrating Lymphocyte
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Ruxotemitide,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : LabCorp | OWL
Deal Size : Inapplicable
Deal Type : Inapplicable
Intratumoral Injection of LTX-315 in Combination With Pembrolizumab in Advanced Melanoma
Details : Undisclosed
Product Name : Undisclosed
Product Type : Peptide
Upfront Cash : Inapplicable
March 12, 2021
Lead Product(s) : Ruxotemitide,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : LabCorp | OWL
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Ruxotemitide,Inapplicable
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Verrica Pharmaceuticals
Deal Size : $113.5 million
Deal Type : Licensing Agreement
Details : The licensing agreement is focused on developing and commercializing LTX-315 for dermatologic oncology indications. Verrica intends to focus initially on basal cell and squamous cell carcinomas as the lead indications for development.
Product Name : Undisclosed
Product Type : Peptide
Upfront Cash : Undisclosed
November 08, 2020
Lead Product(s) : Ruxotemitide,Inapplicable
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Verrica Pharmaceuticals
Deal Size : $113.5 million
Deal Type : Licensing Agreement
Lead Product(s) : Ruxotemitide,Tumor Infiltrating Lymphocytes
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Herlev Hospital
Deal Size : Inapplicable
Deal Type : Inapplicable
LTX-315 and Adoptive T-cell Therapy in Advanced Soft Tissue Sarcoma (ATLAS-IT-04)
Details : Undisclosed
Product Name : Undisclosed
Product Type : Peptide
Upfront Cash : Inapplicable
October 31, 2018
Lead Product(s) : Ruxotemitide,Tumor Infiltrating Lymphocytes
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Herlev Hospital
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Ruxotemitide,Inapplicable
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Theradex | Icon Plc
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Undisclosed
Product Name : Undisclosed
Product Type : Peptide
Upfront Cash : Inapplicable
November 18, 2013
Lead Product(s) : Ruxotemitide,Inapplicable
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Theradex | Icon Plc
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : LTX-109,Inapplicable
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
A Phase II Study to Evaluate the Efficacy and Safety of Two Doses of LTX-109 in Impetigo
Details : Undisclosed
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
March 04, 2013
Lead Product(s) : LTX-109,Inapplicable
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : LTX-109,Inapplicable
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Undisclosed
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
October 18, 2010
Lead Product(s) : LTX-109,Inapplicable
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable