
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : CTM012
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Excalipoint
Deal Size : $857.5 million
Deal Type : Licensing Agreement
Lepu Supplies 2 T-cell Engagers to NewCo in $857M Deal
Details : Under the licensing agreement, Excalipoint will hold the right of two pre-clinical antibody assets, which include CTM012, being evaluated for threatinf neoplasms.
Product Name : CTM012
Product Type : Antibody, Unconjugated
Upfront Cash : $10.0 million
August 01, 2025
Lead Product(s) : CTM012
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Excalipoint
Deal Size : $857.5 million
Deal Type : Licensing Agreement

MRG003 + HX008 Tested In EGFR+ Advanced Penile Squamous Cell Carcinoma
Details : MRG003 is a Antibody-drug Conjugate drug candidate, which is currently being evaluated in Phase I clinical studies for the treatment of Penile Neoplasms.
Product Name : Undisclosed
Product Type : Antibody-drug Conjugate
Upfront Cash : Inapplicable
July 08, 2025

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Lead Product(s) : MRG007
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Arrivent
Deal Size : $1,207.0 million
Deal Type : Licensing Agreement
ArriVent, Lepu Sign Exclusive License for MRG007 in GI Cancer Treatment
Details : Under the terms of the agreement, Lepu Biopharma has granted ArriVent exclusive global rights to develop, manufacture and commercialize MRG007 outside of Greater China.
Product Name : Undisclosed
Product Type : Antibody-drug Conjugate
Upfront Cash : $47.0 million
January 21, 2025
Lead Product(s) : MRG007
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Arrivent
Deal Size : $1,207.0 million
Deal Type : Licensing Agreement

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Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Study Phase : Preclinical
Recipient : DP Technology
Deal Size : Undisclosed
Deal Type : Collaboration
DP Technology Collaborates with Lepu Biopharma to Boost ADC Drug Innovation
Details : The partnership has effectively integrated DP's ADC Linker-Payload design platform with Lepu's ADC technology development platform and advancing the candidate ADC to the clinical stage.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
November 21, 2024
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Recipient : DP Technology
Deal Size : Undisclosed
Deal Type : Collaboration

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Lead Product(s) : Pucotenlimab
Therapeutic Area : Oncology
Study Phase : Approved FDF
Sponsor : Hanx Biopharmaceutical
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Puyouheng (pucotenlimab injection) is a humanized IgG4 monoclonal antibody against human PD-1, bind to PD-1 with high affinity to restore the ability of immune cells to kill cancer cells by blocking the binding of PD-1 to its ligands PD-L1 and PD-L2.
Product Name : Puyouheng
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
July 25, 2022
Lead Product(s) : Pucotenlimab
Therapeutic Area : Oncology
Highest Development Status : Approved FDF
Sponsor : Hanx Biopharmaceutical
Deal Size : Inapplicable
Deal Type : Inapplicable
