
													
															
															Year
															DEALS // DEV.
															Country
															
															Therapeutic Area
															Study Phase
															Deal Type
															Product Type
															Dosage Form
															Lead Product
															Target

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Lead Product(s) : Lenvatinib Mesylate,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Merck & Co
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : LENVIMA (lenvatinib) capsule is an orally available multiple receptor tyrosine kinase inhibitor that inhibits the VEGF receptors and is being evaluated in combination with pembrolizumab in patients with Metastatic Non-Small Cell Lung Cancer.
Product Name : Lenvima
Product Type : Miscellaneous
Upfront Cash : Inapplicable
September 22, 2023
Lead Product(s) : Lenvatinib Mesylate,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Merck & Co
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Lenvatinib Mesylate,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Merck & Co
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : LENVIMA (lenvatinib) Capsule is an orally available multiple receptor tyrosine kinase inhibitor that inhibits the VEGF receptors and evaluating in combination with pembrolizumab in patients With metastatic head and neck squamous cell carcinoma.
Product Name : Lenvima
Product Type : Miscellaneous
Upfront Cash : Inapplicable
August 25, 2023
Lead Product(s) : Lenvatinib Mesylate,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Merck & Co
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Lenvatinib Mesylate,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Lenvima® (lenvatinib), discovered and developed by Eisai, is an orally available multiple receptor tyrosine kinase inhibitor that inhibits the kinase activities of vascular endothelial growth factor (VEGF) receptors VEGFR1 (FLT1), VEGFR2 (KDR), and VEGF...
Product Name : Lenvima
Product Type : Miscellaneous
Upfront Cash : Inapplicable
May 26, 2023
Lead Product(s) : Lenvatinib Mesylate,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Lenvatinib Mesylate,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Lenvima (lenvatinib) is a RTK inhibitor that inhibits the kinase activities of VEGF receptors VEGFR1 (FLT1), VEGFR2 (KDR), and VEGFR3 (FLT4). It also inhibits pathogenic angiogenesis, tumor growth, and cancer progression in addition to their normal cellu...
Product Name : Lenvima
Product Type : Miscellaneous
Upfront Cash : Inapplicable
January 18, 2023
Lead Product(s) : Lenvatinib Mesylate,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Lenvatinib Mesylate
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Final analyses of the RWD study showed that 72.4% of patients treated with LENVIMA (Lenvatinib), a multiple receptor tyrosine kinase inhibitor had Best Overall Response (BOR) reported as a complete (26.9%) or partial (45.5%) response.
Product Name : Lenvima
Product Type : Miscellaneous
Upfront Cash : Inapplicable
October 21, 2022
Lead Product(s) : Lenvatinib Mesylate
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Lenvatinib Mesylate,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Merck & Co
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : In final analysis, there was improvement for one of dual primary endpoints, overall survival, for patients treated with Lenvima (Lenvatinib) plus KEYTRUDA versus Lenvima monotherapy; however, results did not meet statistical significance per pre-specifie...
Product Name : Lenvima
Product Type : Miscellaneous
Upfront Cash : Inapplicable
September 12, 2022
Lead Product(s) : Lenvatinib Mesylate,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Merck & Co
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Lenvatinib Mesylate,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Eisai Presents New Data From its Oncology Portfolio and Pipeline at ESMO Congress 2022
Details : Two Mini-Oral Presentations on the Pivotal Phase 3 CLEAR and Study 309/KEYNOTE-775 Trials Demonstrate the clinical benefit of lenvima (lenvatinib) plus pembrolizumab and the combination’s potential across difficult-to-treat cancers.
Product Name : Lenvima
Product Type : Miscellaneous
Upfront Cash : Inapplicable
September 06, 2022
Lead Product(s) : Lenvatinib Mesylate,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Nofazinlimab,Lenvatinib Mesylate
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : CS1003 (nofazinlimab) is a humanized recombinant IgG4 monoclonal antibody targeting human programmed cell death protein 1 (PD-1) being developed in combination with lenvatinib as first-line treatment for patients with advanced hepatocellular carcinoma.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
March 18, 2022
Lead Product(s) : Nofazinlimab,Lenvatinib Mesylate
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Lenvatinib Mesylate,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Approved FDF
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : The approval is based on results from the pivotal Phase 3 CLEAR (Study 307)/KEYNOTE581 trial, in which LENVIMA plus KEYTRUDA demonstrated statistically significant improvements versus sunitinib in the primary efficacy outcome measure of progression-free ...
Product Name : Lenvima
Product Type : Miscellaneous
Upfront Cash : Inapplicable
February 25, 2022
Lead Product(s) : Lenvatinib Mesylate,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Approved FDF
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Lenvatinib Mesylate,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Approved FDF
Sponsor : Merck & Co
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : The approval is based on results from the CLEAR (Study 307)/KEYNOTE-581 trial evaluating the combination of LENVIMA plus KEYTRUDA, for the first-line treatment of patients with advanced RCC.
Product Name : Lenvima
Product Type : Miscellaneous
Upfront Cash : Inapplicable
January 31, 2022
Lead Product(s) : Lenvatinib Mesylate,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Approved FDF
Sponsor : Merck & Co
Deal Size : Inapplicable
Deal Type : Inapplicable
