[{"orgOrder":0,"company":"L.E.A.F. Pharmaceuticals","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2020","type":"Inapplicable","leadProduct":"Gamma L-Pentaglutamated Pemetrexed","moa":"Thymidylate synthase","graph1":"Oncology","graph2":"Preclinical","graph3":"L.E.A.F. Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"L.E.A.F. Pharmaceuticals \/ Inapplicable","highestDevelopmentStatusID":"4","companyTruncated":"L.E.A.F. Pharmaceuticals \/ Inapplicable"}]

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                          01

                          BPI Europe
                          Not Confirmed
                          BPI Europe
                          Not Confirmed

                          Details : LEAF-1401 is a liposomal formulation of gamma L-pentaglutamated pemetrexed. Gamma L-polyglutamated pemetrexed has been shown to be 80-times more potent than pemetrexed in inhibiting thymidylate synthase.

                          Product Name : LEAF-1401

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          September 06, 2020

                          Lead Product(s) : Gamma L-Pentaglutamated Pemetrexed

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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