
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : KAYO-1732
Therapeutic Area : Endocrinology
Study Phase : Preclinical
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Kayothera Nominates KAYO-1732 Oral Inhibitor for Type 2 Diabetes Pipeline
Details : KAYO-1732 is a novel, orally-available, small molecule inhibitor of the ALDH1A3 enzyme, developed for the treatment of type 2 diabetes and cardiovascular disorders.
Product Name : KAYO-1732
Product Type : Miscellaneous
Upfront Cash : Inapplicable
September 23, 2025
Lead Product(s) : KAYO-1732
Therapeutic Area : Endocrinology
Highest Development Status : Preclinical
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : KAYO-1609
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : KAYO-1609 is the first-in-class, oral inhibitor of the retinoid pathway, which is investigated for the treatment of genetically-defined cancers. Company expects to file IND application with the U.S. Food & Drug Administration (FDA) by the end of 2024.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
September 18, 2023
Lead Product(s) : KAYO-1609
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Undisclosed
Therapeutic Area : Endocrinology
Study Phase : Undisclosed
Sponsor : NIH NIDDK
Deal Size : Undisclosed
Deal Type : Funding
Details : The net funding will support the advancement of KayoThera’s pipeline of first-in-class antagonists of the retinoid pathway as novel oral therapies for Type 2 Diabetes.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
July 19, 2023
Lead Product(s) : Undisclosed
Therapeutic Area : Endocrinology
Highest Development Status : Undisclosed
Sponsor : NIH NIDDK
Deal Size : Undisclosed
Deal Type : Funding

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Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Study Phase : Undisclosed
Sponsor : Accelerator Life Science Partners
Deal Size : $5.2 million
Deal Type : Series A Financing
Details : The net funding will support the advancement of KayoThera’s development programs in diabetes and oncology. KayoThera is developing first-in-class, oral, small molecule inhibitors of the retinoid pathway.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
July 19, 2023
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Undisclosed
Sponsor : Accelerator Life Science Partners
Deal Size : $5.2 million
Deal Type : Series A Financing

Details : KayoThera will focus its therapeutic development efforts on its lead oncology program to further advance the technology towards a product that will benefit patients with late-stage and metastatic cancers.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
March 16, 2022
