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    [{"orgOrder":0,"company":"Jiangsu Simcere Pharmaceutical","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"CHINA","productType":"Other Small Molecule","year":"2022","type":"Inapplicable","leadProduct":"SIM0417","moa":"3CLpro","graph1":"Infections and Infectious Diseases","graph2":"Phase I","graph3":"Jiangsu Simcere Pharmaceutical","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Oral","sponsorNew":"Jiangsu Simcere Pharmaceutical \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"Jiangsu Simcere Pharmaceutical \/ Inapplicable"},{"orgOrder":0,"company":"Jiangsu Simcere Pharmaceutical","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"CHINA","productType":"Other Small 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Inapplicable"},{"orgOrder":0,"company":"Jiangsu Simcere Pharmaceutical","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Cardiology\/Vascular Diseases","country":"CHINA","productType":"Other Small Molecule","year":"2024","type":"Inapplicable","leadProduct":"Edaravone","moa":"||Lipid peroxidation","graph1":"Cardiology\/Vascular Diseases","graph2":"Approved FDF","graph3":"Jiangsu Simcere Pharmaceutical","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Cardiovascular Diseases","amount2New":0,"dosageForm":"Sublingual Tablet","sponsorNew":"Jiangsu Simcere Pharmaceutical \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"Jiangsu Simcere Pharmaceutical \/ Inapplicable"},{"orgOrder":0,"company":"Jiangsu Simcere Pharmaceutical","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Cardiology\/Vascular Diseases","country":"CHINA","productType":"Other Small 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Brigham","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"CHINA","productType":"Undisclosed","year":"2023","type":"Agreement","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Oncology","graph2":"Discovery","graph3":"Jiangsu Simcere Pharmaceutical","amount2":0,"highestDevelopmentShortName":"Discovery","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral","sponsorNew":"Jiangsu Simcere Pharmaceutical \/ Mass General Brigham","highestDevelopmentStatusID":"2","companyTruncated":"Jiangsu Simcere Pharmaceutical \/ Mass General Brigham"},{"orgOrder":0,"company":"Jiangsu Simcere Pharmaceutical","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"CHINA","productType":"Antibody","year":"2022","type":"Inapplicable","leadProduct":"SIM0237","moa":"PD-L1\/IL-15 receptor","graph1":"Oncology","graph2":"IND Enabling","graph3":"Jiangsu Simcere Pharmaceutical","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Jiangsu Simcere Pharmaceutical \/ Inapplicable","highestDevelopmentStatusID":"5","companyTruncated":"Jiangsu Simcere Pharmaceutical \/ Inapplicable"},{"orgOrder":0,"company":"Jiangsu Simcere Pharmaceutical","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"CHINA","productType":"Antibody","year":"2024","type":"Inapplicable","leadProduct":"Cetuximab Beta","moa":"||EGFR","graph1":"Oncology","graph2":"Approved FDF","graph3":"Jiangsu Simcere Pharmaceutical","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Jiangsu Simcere Pharmaceutical \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"Jiangsu Simcere Pharmaceutical \/ Inapplicable"},{"orgOrder":0,"company":"Jiangsu Simcere Pharmaceutical","sponsor":"AbbVie Inc","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"CHINA","productType":"Antibody","year":"2025","type":"Licensing Agreement","leadProduct":"SIM0500","moa":"GPRC5D\/BCMA\/CD3","graph1":"Oncology","graph2":"Phase I","graph3":"Jiangsu Simcere Pharmaceutical","amount2":1.0600000000000001,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":1.0600000000000001,"dosageForm":"Undisclosed","sponsorNew":"Jiangsu Simcere Pharmaceutical \/ AbbVie Inc","highestDevelopmentStatusID":"6","companyTruncated":"Jiangsu Simcere Pharmaceutical \/ AbbVie Inc"},{"orgOrder":0,"company":"Jiangsu Simcere Pharmaceutical","sponsor":"NextCure","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"CHINA","productType":"Antibody-drug Conjugate","year":"2025","type":"Partnership","leadProduct":"SIM0505","moa":"CDH6","graph1":"Oncology","graph2":"Phase I","graph3":"Jiangsu Simcere Pharmaceutical","amount2":0.75,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0.75,"dosageForm":"Injection","sponsorNew":"Jiangsu Simcere Pharmaceutical \/ NextCure","highestDevelopmentStatusID":"6","companyTruncated":"Jiangsu Simcere Pharmaceutical \/ NextCure"},{"orgOrder":0,"company":"Jiangsu Simcere Pharmaceutical","sponsor":"Connect Biopharma","pharmaFlowCategory":"D","therapeuticArea":"Dermatology","country":"CHINA","productType":"Antibody","year":"2025","type":"Licensing Agreement","leadProduct":"Rademikibart","moa":"IL-4-alpha receptor","graph1":"Dermatology","graph2":"Phase III","graph3":"Jiangsu Simcere Pharmaceutical","amount2":0.02,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Dermatology","amount2New":0.02,"dosageForm":"Subcutaneous Injection","sponsorNew":"Jiangsu Simcere Pharmaceutical \/ Jiangsu Simcere Pharmaceutical","highestDevelopmentStatusID":"10","companyTruncated":"Jiangsu Simcere Pharmaceutical \/ Jiangsu Simcere Pharmaceutical"}]

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                            01

                            Jiangsu Simcere Pharmaceutical

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                            ACS Fall 2025
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                            Jiangsu Simcere Pharmaceutical

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                            Lead Product(s) : Rademikibart

                            Therapeutic Area : Dermatology

                            Study Phase : Phase III

                            Recipient : Connect Biopharma

                            Deal Size : $21.0 million

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Simcere Files NDA in China for Rademikibart; Connect Biopharma gets Milestone

                            Details : Under the licensing agreement, Simcere was granted exclusive rights to develop, manufacture, and commercialize CBP-201 (rademikibart) for all indications in Greater China.

                            Product Name : CBP-201

                            Product Type : Antibody

                            Upfront Cash : $141.0 million

                            July 09, 2025

                            Lead Product(s) : Rademikibart

                            Therapeutic Area : Dermatology

                            Highest Development Status : Phase III

                            Recipient : Connect Biopharma

                            Deal Size : $21.0 million

                            Deal Type : Licensing Agreement

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                            02

                            Jiangsu Simcere Pharmaceutical

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                            ACS Fall 2025
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                            ACS Fall 2025
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                            Lead Product(s) : SIM0505

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : NextCure

                            Deal Size : $745.0 million

                            Deal Type : Partnership

                            DEALS_DEV arrow-down

                            NextCure Joins China-ADC Gold Rush with $745M Simcere Deal

                            Details : The partership aims to develop SIM0505, a novel antibody-drug conjugate (ADC) targeting CDH6 (cadherin-6 or K-cadherin) for the treatment of solid tumors.

                            Product Name : SIM0505

                            Product Type : Antibody-drug Conjugate

                            Upfront Cash : Undisclosed

                            June 16, 2025

                            Lead Product(s) : SIM0505

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : NextCure

                            Deal Size : $745.0 million

                            Deal Type : Partnership

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                            03

                            Jiangsu Simcere Pharmaceutical

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                            ACS Fall 2025
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                            ACS Fall 2025
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                            Lead Product(s) : SIM0500

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : AbbVie Inc

                            Deal Size : $1,055.0 million

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            AbbVie Pens $1B deal for Simcere’s Phase 1 T-Cell Engager

                            Details : Simcere has option to license agreement with Abbvie to develop SIM0500, an investigational new drug candidate. It is being evaluated in patients with relapsed or refractory multiple myeloma.

                            Product Name : SIM0500

                            Product Type : Antibody

                            Upfront Cash : Undisclosed

                            January 13, 2025

                            Lead Product(s) : SIM0500

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : AbbVie Inc

                            Deal Size : $1,055.0 million

                            Deal Type : Licensing Agreement

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                            04

                            Jiangsu Simcere Pharmaceutical

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                            ACS Fall 2025
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                            Jiangsu Simcere Pharmaceutical

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                            ACS Fall 2025
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                            Lead Product(s) : Edaravone,Dexborneol

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Simcere’s Sanbexin® Approved in China for Acute Ischemic Stroke

                            Details : Sanbexin (a combination of edaravone and dexborneol) is a small molecule, sublingual tablet, which is being evaluated for the treatment of acute ischemic stroke.

                            Product Name : Sanbexin

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            December 04, 2024

                            Lead Product(s) : Edaravone,Dexborneol

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Jiangsu Simcere Pharmaceutical

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                            ACS Fall 2025
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                            Jiangsu Simcere Pharmaceutical

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                            ACS Fall 2025
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                            Lead Product(s) : Cetuximab Beta,Calcium Folinate,Irinotecan Hydrochloride

                            Therapeutic Area : Oncology

                            Study Phase : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Simcere Zaiming Announce Approval of Cetuximab Beta in China by the NMPA

                            Details : Enlituo (cetuximab beta) is a EGFR inhibitor indicated in combination with the FOLFIRI regimen as a first-line treatment for RAS/BRAF wild-type metastatic colorectal cancer (mCRC).

                            Product Name : Enlituo

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            June 26, 2024

                            Lead Product(s) : Cetuximab Beta,Calcium Folinate,Irinotecan Hydrochloride

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Jiangsu Simcere Pharmaceutical

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                            ACS Fall 2025
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                            Jiangsu Simcere Pharmaceutical

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                            ACS Fall 2025
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                            Lead Product(s) : Edaravone,Dexborneol

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Sanbexin Sublingual Tablets Receive Breakthrough Therapy Designation from FDA

                            Details : Sanbexin (a combination of edaravone and dexborneol) is a small molecule, sublingual tablet, which is being evaluated for the treatment of acute ischemic stroke.

                            Product Name : Sanbexin

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            May 09, 2024

                            Lead Product(s) : Edaravone,Dexborneol

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Jiangsu Simcere Pharmaceutical

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                            ACS Fall 2025
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                            Jiangsu Simcere Pharmaceutical

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                            ACS Fall 2025
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                            Lead Product(s) : Edaravone,Dexborneol

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase III

                            Sponsor : NeuroDerm

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Findings of a Phase III Clinical Study of Sanbexin® Sublingual Tablets Published in JAMA

                            Details : Sanbexin (a combination of edaravone and dexborneol) is a small molecule, sublingual tablet, which is being evaluated for the treatment of acute ischemic stroke.

                            Product Name : Sanbexin

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            February 20, 2024

                            Lead Product(s) : Edaravone,Dexborneol

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase III

                            Sponsor : NeuroDerm

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Jiangsu Simcere Pharmaceutical

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                            ACS Fall 2025
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                            Jiangsu Simcere Pharmaceutical

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                            ACS Fall 2025
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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Oncology

                            Study Phase : Discovery

                            Sponsor : Mass General Brigham

                            Deal Size : Undisclosed

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Simcere Pharmaceutical Group Announces Sponsored Research Agreement with Boston-based Mass General Brigham

                            Details : The agreement aims to establish a mutually beneficial partnership that will advance scientific research and create new treatment options for patients with cancer, autoimmune and CNS diseases.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Undisclosed

                            December 06, 2023

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Oncology

                            Highest Development Status : Discovery

                            Sponsor : Mass General Brigham

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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                            09

                            Jiangsu Simcere Pharmaceutical

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                            ACS Fall 2025
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                            Jiangsu Simcere Pharmaceutical

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                            ACS Fall 2025
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                            Lead Product(s) : SIM0235,Pembrolizumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Merck & Co

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Simcere Zaiming Announces Clinical Collaboration to Evaluate SIM0235, a TNFR2 Monoclonal Antibody, in Combinat...

                            Details : Under the agreement, MSD will supply KEYTRUDA and collaborate with Simcere to evaluate the combination of SIM0235, a potential first-in-class humanized anti-TNFR2 mAb, and MSD's anti-PD-1 therapy, KEYTRUDA® (pembrolizumab), in patients with advanced sol...

                            Product Name : SIM0235

                            Product Type : Antibody

                            Upfront Cash : Undisclosed

                            March 14, 2023

                            Lead Product(s) : SIM0235,Pembrolizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Merck & Co

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            10

                            Jiangsu Simcere Pharmaceutical

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                            ACS Fall 2025
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                            Jiangsu Simcere Pharmaceutical

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                            ACS Fall 2025
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                            Lead Product(s) : SSD8432,Ritonavir

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase II/ Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Phase II/III Clinical Trial of Simcere's 3CL-Targeting Anti-SARS-COV-2 Drug Candidate Complete All Patients En...

                            Details : XIANNUOXIN is a combination packaged drug of a small molecule anti- SARS-CoV-2 drug candidate SSD8432 and Ritonavir, this candidate is targeted 3CL protease which is essential for SARS-CoV-2 viral replication.

                            Product Name : Xiannuoxin

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            December 20, 2022

                            Lead Product(s) : SSD8432,Ritonavir

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase II/ Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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