
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : JADE101
Therapeutic Area : Nephrology
Study Phase : Phase I
Sponsor : Janus Henderson Investors
Deal Size : $135.0 million
Deal Type : Public Offering
Jade Biosciences Announces $135 Million Private Placement
Details : In the public offering, JADE101, an unconjugated antibody targeting APRIL, aims to advance treatment for IgA nephropathy.
Product Name : JADE101
Product Type : Antibody, Unconjugated
Upfront Cash : Undisclosed
October 07, 2025
Lead Product(s) : JADE101
Therapeutic Area : Nephrology
Highest Development Status : Phase I
Sponsor : Janus Henderson Investors
Deal Size : $135.0 million
Deal Type : Public Offering

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Lead Product(s) : JADE101
Therapeutic Area : Undisclosed
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
A Phase 1 Study of JADE101 in Healthy Participants
Details : JADE101 is a Antibody drug candidate, which is currently being evaluated in Phase I clinical studies for the treatment of unspecified medical condition.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
July 10, 2025
Lead Product(s) : JADE101
Therapeutic Area : Undisclosed
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : JADE-001
Therapeutic Area : Nephrology
Study Phase : IND Enabling
Recipient : Aerovate Therapeutics
Deal Size : Undisclosed
Deal Type : Merger
Jade Merges with Aerovate, Secures $300M in Private Placement Funding
Details : The combined company will focus on advancing Jade’s portfolio of novel biologics, including JADE-001, a promising anti-APRIL monoclonal antibody for IgA nephropathy.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
April 28, 2025
Lead Product(s) : JADE-001
Therapeutic Area : Nephrology
Highest Development Status : IND Enabling
Recipient : Aerovate Therapeutics
Deal Size : Undisclosed
Deal Type : Merger

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Lead Product(s) : Mipletamig
Therapeutic Area : Oncology
Study Phase : Phase I
Recipient : Aptevo Therapeutics
Deal Size : $2.0 million
Deal Type : Public Offering
Aptevo Closes $2M Direct Offering Priced At-The-Market Under Nasdaq Rules
Details : The net proceeds from the offering will be used to advance the clinical development of APVO436 (mipletamig), being evaluated for the treatment of Acute Myeloid Leukemia.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Undisclosed
April 22, 2025
Lead Product(s) : Mipletamig
Therapeutic Area : Oncology
Highest Development Status : Phase I
Recipient : Aptevo Therapeutics
Deal Size : $2.0 million
Deal Type : Public Offering

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Lead Product(s) : JADE-001
Therapeutic Area : Nephrology
Study Phase : Preclinical
Recipient : Aerovate Therapeutics
Deal Size : Undisclosed
Deal Type : Merger
Aerovate Shareholders Approve Merger with Jade Biosciences and All Proposals
Details : The combined company will focus on advancing Jade’s portfolio of novel biologics, including JADE-001, a promising anti-APRIL monoclonal antibody for IgA nephropathy.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
April 21, 2025
Lead Product(s) : JADE-001
Therapeutic Area : Nephrology
Highest Development Status : Preclinical
Recipient : Aerovate Therapeutics
Deal Size : Undisclosed
Deal Type : Merger

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Lead Product(s) : JADE-001
Therapeutic Area : Nephrology
Study Phase : Preclinical
Recipient : Aerovate Therapeutics
Deal Size : Undisclosed
Deal Type : Merger
Aerovate Therapeutics and Jade Biosciences Announce Merger Agreement
Details : The combined company will focus on advancing Jade’s portfolio of novel biologics, including JADE-001, a promising anti-APRIL monoclonal antibody for IgA nephropathy.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
October 31, 2024
Lead Product(s) : JADE-001
Therapeutic Area : Nephrology
Highest Development Status : Preclinical
Recipient : Aerovate Therapeutics
Deal Size : Undisclosed
Deal Type : Merger

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Lead Product(s) : Undisclosed
Therapeutic Area : Immunology
Study Phase : Discovery
Sponsor : Fairmount Funds Management LLC
Deal Size : $80.0 million
Deal Type : Financing
Jade Biosciences Launches with $80M to Develop Therapies for Autoimmune Diseases
Details : The funding will be used to support Jade's plans to develop targeted therapies for indications with high unmet need across inflammation and immunology.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
August 01, 2024
Lead Product(s) : Undisclosed
Therapeutic Area : Immunology
Highest Development Status : Discovery
Sponsor : Fairmount Funds Management LLC
Deal Size : $80.0 million
Deal Type : Financing

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