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Find Clinical Drug Pipeline Developments & Deals by J Ints Bio
The license agreement is for JIN-A04, an oral Tyrosine Kinase Inhibitor (TKI) targeting non-small cell lung cancer carrying HER2 mutations. There is currently no oral drug approved to date.
JIN-A02 is a novel orally administered 4th Generation EGFR TKI targeting C797S mutations in NSCLC. 'JIN-A02' have a high brain penetrance and is expected to become the most promising 4th-generation EGFR TKI in NSCLC patients with limited or no viable treatment options.
JIN-A02 is a novel orally administered EGFR TKI that targets NSCLC cancers harboring C797S mutation, showed strong inhibitory activities against NSCLC cancer cell-lines harboring double and triple mutations with C797S mutations in in-vitro studies.
JIN-A02 is a novel orally administered 4th generation EGFR TKI that targets NSCLC cancers harboring C797S mutation. C797S is a mutation that occur after the use of 3rd generation EGFR TKIs such as Osimertinib and Lazertinib, resulting in tumor resistance and disease relapse.