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S.p.A","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"ITALY","productType":"Miscellaneous","year":"2024","type":"Inapplicable","leadProduct":"Givinostat HCl","moa":"HDAC","graph1":"Genetic Disease","graph2":"Approved FDF","graph3":"Italfarmaco S.p.A","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Suspension","sponsorNew":"Italfarmaco S.p.A \/ Undisclosed","highestDevelopmentStatusID":"15","companyTruncated":"Italfarmaco S.p.A \/ Undisclosed"},{"orgOrder":0,"company":"Italfarmaco S.p.A","sponsor":"Medis","pharmaFlowCategory":"D","therapeuticArea":"Genetic Disease","country":"ITALY","productType":"Miscellaneous","year":"2025","type":"Agreement","leadProduct":"Givinostat HCl","moa":"HDAC","graph1":"Genetic Disease","graph2":"Approved FDF","graph3":"Italfarmaco S.p.A","amount2":0,"highestDevelopmentShortName":"Approved 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S.p.A","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"ITALY","productType":"Miscellaneous","year":"2025","type":"Inapplicable","leadProduct":"Givinostat HCl","moa":"HDAC","graph1":"Oncology","graph2":"Approved FDF","graph3":"Italfarmaco S.p.A","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Suspension","sponsorNew":"Italfarmaco S.p.A \/ Undisclosed","highestDevelopmentStatusID":"15","companyTruncated":"Italfarmaco S.p.A \/ Undisclosed"},{"orgOrder":0,"company":"Italfarmaco S.p.A","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"ITALY","productType":"Miscellaneous","year":"2025","type":"Inapplicable","leadProduct":"Givinostat HCl","moa":"HDAC","graph1":"Genetic Disease","graph2":"Approved FDF","graph3":"Italfarmaco S.p.A","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Suspension","sponsorNew":"Italfarmaco S.p.A \/ Undisclosed","highestDevelopmentStatusID":"15","companyTruncated":"Italfarmaco S.p.A \/ Undisclosed"},{"orgOrder":0,"company":"Italfarmaco S.p.A","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"ITALY","productType":"Miscellaneous","year":"2021","type":"Inapplicable","leadProduct":"Givinostat HCl","moa":"HDAC","graph1":"Genetic Disease","graph2":"Approved FDF","graph3":"Italfarmaco S.p.A","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Suspension","sponsorNew":"Italfarmaco S.p.A \/ Undisclosed","highestDevelopmentStatusID":"15","companyTruncated":"Italfarmaco S.p.A \/ Undisclosed"},{"orgOrder":0,"company":"Italfarmaco S.p.A","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Genetic 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S.p.A \/ Italfarmaco S.p.A","highestDevelopmentStatusID":"3","companyTruncated":"Italfarmaco S.p.A \/ Italfarmaco S.p.A"},{"orgOrder":0,"company":"Italfarmaco S.p.A","sponsor":"Nerviano Medical Sciences","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"ITALY","productType":"Undisclosed","year":"2023","type":"Licensing Agreement","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Oncology","graph2":"Discovery","graph3":"Italfarmaco S.p.A","amount2":0,"highestDevelopmentShortName":"Discovery","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Italfarmaco S.p.A \/ Italfarmaco S.p.A","highestDevelopmentStatusID":"2","companyTruncated":"Italfarmaco S.p.A \/ Italfarmaco S.p.A"},{"orgOrder":0,"company":"Italfarmaco S.p.A","sponsor":"Multicare","pharmaFlowCategory":"D","therapeuticArea":"Genetic Disease","country":"ITALY","productType":"Miscellaneous","year":"2025","type":"Agreement","leadProduct":"Givinostat HCl","moa":"HDAC","graph1":"Genetic Disease","graph2":"Approved FDF","graph3":"Italfarmaco S.p.A","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Suspension","sponsorNew":"Italfarmaco S.p.A \/ Multicare","highestDevelopmentStatusID":"15","companyTruncated":"Italfarmaco S.p.A \/ Multicare"}]

Find Clinical Drug Pipeline Developments & Deals by Italfarmaco S.p.A

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          The MedTech Conference
                          Not Confirmed
                          The MedTech Conference
                          Not Confirmed

                          Details : Multicare Pharma will support the regulatory approval in Brazil and distribute Duvyzat (givinostat), Italfarmaco’s novel histone deacetylase (HDAC) inhibitor to treat Duchenne muscular dystrophy.

                          Product Name : Duvyzat

                          Product Type : Miscellaneous

                          Upfront Cash : Undisclosed

                          September 16, 2025

                          Lead Product(s) : Givinostat HCl

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Approved FDF

                          Sponsor : Multicare

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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                          02

                          The MedTech Conference
                          Not Confirmed
                          The MedTech Conference
                          Not Confirmed

                          Details : Duvyzat (givinostat HCl)is a histone deacetylase inhibitor indicated for the treatment of Duchenne muscular dystrophy (DMD) in patients 6 years of age and older.

                          Product Name : Duvyzat

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          June 06, 2025

                          Lead Product(s) : Givinostat HCl

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          The MedTech Conference
                          Not Confirmed
                          The MedTech Conference
                          Not Confirmed

                          Details : Duvyzat (givinostat HCl) is a histone deacetylase inhibitor, being investigated for the treatment of polycythaemia vera.

                          Product Name : Duvyzat

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          May 06, 2025

                          Lead Product(s) : Givinostat HCl

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          The MedTech Conference
                          Not Confirmed
                          The MedTech Conference
                          Not Confirmed

                          Details : Duvyzat (givinostat) is a novel histone deacetylase (HDAC) inhibitor, which is being evaluated for the treatment of patients 6 years or older with Duchenne muscular dystrophy.

                          Product Name : Duvyzat

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          April 25, 2025

                          Lead Product(s) : Givinostat HCl

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          The MedTech Conference
                          Not Confirmed
                          The MedTech Conference
                          Not Confirmed

                          Details : Under the agreement, Medis will have exclusive distribution rights of Duvyzat (Givinostat HCl). It is being indicated for the treatment of DMD.

                          Product Name : Duvyzat

                          Product Type : Miscellaneous

                          Upfront Cash : Undisclosed

                          March 18, 2025

                          Lead Product(s) : Givinostat HCl

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Approved FDF

                          Sponsor : Medis

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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                          06

                          The MedTech Conference
                          Not Confirmed
                          The MedTech Conference
                          Not Confirmed

                          Details : Duvyzat (givinostat) is a novel histone deacetylase (HDAC) inhibitor, which is being evaluated for the treatment of patients 6 years or older with Duchenne muscular dystrophy.

                          Product Name : Duvyzat

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          July 25, 2024

                          Lead Product(s) : Givinostat HCl

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          The MedTech Conference
                          Not Confirmed
                          The MedTech Conference
                          Not Confirmed

                          Details : Italfarmaco collaborates with Iktos to develop next-generation, small molecule HDAC inhibitors for various non-oncological diseases, including diseases affecting the central nervous system.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          June 18, 2024

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Neurology

                          Highest Development Status : Discovery Platform

                          Recipient : Iktos

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          08

                          The MedTech Conference
                          Not Confirmed
                          The MedTech Conference
                          Not Confirmed

                          Details : Duvyzat (givinostat) is a novel histone deacetylase (HDAC) inhibitor, which is being evaluated for the treatment of patients 6 years or older with Duchenne muscular dystrophy.

                          Product Name : Duvyzat

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          March 21, 2024

                          Lead Product(s) : Givinostat HCl

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          The MedTech Conference
                          Not Confirmed
                          The MedTech Conference
                          Not Confirmed

                          Details : Under the terms of the agreement, ITF will use NMS’s proprietary linker-payload technology to develop a novel peptide-drug conjugate (PDC) to bring first- and best-in-class personalized medicines to cancer patients.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          December 14, 2023

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Oncology

                          Highest Development Status : Discovery

                          Recipient : Nerviano Medical Sciences

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

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                          10

                          The MedTech Conference
                          Not Confirmed
                          The MedTech Conference
                          Not Confirmed

                          Details : Under the terms of the agreement, Italfarmaco gains the exclusive rights to commercialize Rivastigmine MD in Germany, Italy, Portugal and Greece. Italfarmaco will also have a preferred right to market Rivastigmine MD in Chile and Vietnam.

                          Product Name : Rivalif

                          Product Type : Miscellaneous

                          Upfront Cash : Undisclosed

                          March 16, 2021

                          Lead Product(s) : Rivastigmine

                          Therapeutic Area : Neurology

                          Highest Development Status : Approved FDF

                          Recipient : Luye Pharma

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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