[{"orgOrder":0,"company":"Apontis Pharma","sponsor":"Midas Pharma","pharmaFlowCategory":"D","therapeuticArea":"Cardiology\/Vascular Diseases","country":"GERMANY","productType":"Miscellaneous","year":"2021","type":"Partnership","leadProduct":"Candesartan Cilexetil","moa":"||Type-1 angiotensin II receptor","graph1":"Cardiology\/Vascular Diseases","graph2":"Phase III","graph3":"Apontis Pharma","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Cardiovascular Diseases","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Apontis Pharma \/ Midas Pharma","highestDevelopmentStatusID":"10","companyTruncated":"Apontis Pharma \/ Midas Pharma"},{"orgOrder":0,"company":"George Medicines","sponsor":"Piramal Pharma Solutions","pharmaFlowCategory":"DU","therapeuticArea":"Cardiology\/Vascular Diseases","country":"UNITED KINGDOM","productType":"Miscellaneous","year":"2025","type":"Inapplicable","leadProduct":"Telmisartan","moa":"||Type-1 angiotensin II receptor","graph1":"Cardiology\/Vascular Diseases","graph2":"Approved FDF","graph3":"George Medicines","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Cardiovascular Diseases","amount2New":0,"dosageForm":"Tablet","sponsorNew":"George Medicines \/ Piramal Pharma Solutions","highestDevelopmentStatusID":"15","companyTruncated":"George Medicines \/ Piramal Pharma Solutions"},{"orgOrder":0,"company":"Shenzhen Ausa Pharmed Co.,Ltd","sponsor":"Peking University First Hospital | Second Affiliated Hospital, Nanchang University | The First People's Hospital of Lianyungang | The Affiliated Hospital Of Guizhou Medical University | Lianyungang Oriental Hospital | Tengzhou Central People's Hospital | ","pharmaFlowCategory":"DU","therapeuticArea":"Cardiology\/Vascular Diseases","country":"CHINA","productType":"Miscellaneous","year":"2021","type":"Inapplicable","leadProduct":"Amlodipine Besylate","moa":"Voltage-gated L-type calcium channel","graph1":"Cardiology\/Vascular Diseases","graph2":"Phase IV","graph3":"Shenzhen Ausa Pharmed Co.,Ltd","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Cardiovascular Diseases","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Shenzhen Ausa Pharmed Co.,Ltd \/ Peking University First Hospital | Second Affiliated Hospital, Nanchang University | The First People's Hospital of Lianyungang | The Affiliated Hospital Of Guizhou Medical University | Lianyungang Oriental Hospital | Tengzhou Central People's Hospital | ","highestDevelopmentStatusID":"11","companyTruncated":"Shenzhen Ausa Pharmed Co.,Ltd \/ Peking University First Hospital | Second Affiliated Hospital, Nanchang University | The First People's Hospital of Lianyungang | The Affiliated Hospital Of Guizhou Medical University | Lianyungang Oriental Hospital | Tengzhou Central People's Hospital | "},{"orgOrder":0,"company":"Shenzhen Ausa Pharmed Co.,Ltd","sponsor":"Peking University First Hospital | Second Affiliated Hospital, Nanchang University | The First People's Hospital of Lianyungang | The Affiliated Hospital Of Guizhou Medical University | Lianyungang Oriental Hospital | Tengzhou Central People's Hospital | ","pharmaFlowCategory":"DU","therapeuticArea":"Cardiology\/Vascular Diseases","country":"CHINA","productType":"Miscellaneous","year":"2021","type":"Inapplicable","leadProduct":"Amlodipine Besylate","moa":"Voltage-gated L-type calcium channel","graph1":"Cardiology\/Vascular Diseases","graph2":"Phase IV","graph3":"Shenzhen Ausa Pharmed Co.,Ltd","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Cardiovascular Diseases","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Shenzhen Ausa Pharmed Co.,Ltd \/ Peking University First Hospital | Second Affiliated Hospital, Nanchang University | The First People's Hospital of Lianyungang | The Affiliated Hospital Of Guizhou Medical University | Lianyungang Oriental Hospital | Tengzhou Central People's Hospital | ","highestDevelopmentStatusID":"11","companyTruncated":"Shenzhen Ausa Pharmed Co.,Ltd \/ Peking University First Hospital | Second Affiliated Hospital, Nanchang University | The First People's Hospital of Lianyungang | The Affiliated Hospital Of Guizhou Medical University | Lianyungang Oriental Hospital | Tengzhou Central People's Hospital | "},{"orgOrder":0,"company":"Overseas Pharma","sponsor":"Health Start Pharmaceutical Technology","pharmaFlowCategory":"DU","therapeuticArea":"Cardiology\/Vascular Diseases","country":"INDIA","productType":"Miscellaneous","year":"2022","type":"Inapplicable","leadProduct":"Amlodipine Besylate","moa":"Voltage-gated L-type calcium channel","graph1":"Cardiology\/Vascular Diseases","graph2":"Phase I","graph3":"Overseas Pharma","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Cardiovascular Diseases","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Overseas Pharma \/ Health Start Pharmaceutical Technology","highestDevelopmentStatusID":"6","companyTruncated":"Overseas Pharma \/ Health Start Pharmaceutical Technology"},{"orgOrder":0,"company":"Alembic Pharmaceuticals Limited","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Cardiology\/Vascular Diseases","country":"INDIA","productType":"Miscellaneous","year":"2025","type":"Inapplicable","leadProduct":"Amlodipine Besylate","moa":"||Voltage-gated L-type calcium channel","graph1":"Cardiology\/Vascular Diseases","graph2":"Approved FDF","graph3":"Alembic Pharmaceuticals Limited","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Cardiovascular Diseases","amount2New":0,"dosageForm":"Tablet, Film Coated","sponsorNew":"Alembic Pharmaceuticals Limited \/ Undisclosed","highestDevelopmentStatusID":"15","companyTruncated":"Alembic Pharmaceuticals Limited \/ Undisclosed"},{"orgOrder":0,"company":"CMP Pharma","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Cardiology\/Vascular Diseases","country":"U.S.A","productType":"Miscellaneous","year":"2022","type":"Inapplicable","leadProduct":"Amlodipine Besylate","moa":"Voltage-gated L-type calcium channel","graph1":"Cardiology\/Vascular Diseases","graph2":"Approved FDF","graph3":"CMP Pharma","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Cardiovascular Diseases","amount2New":0,"dosageForm":"Solution","sponsorNew":"CMP Pharma \/ Undisclosed","highestDevelopmentStatusID":"15","companyTruncated":"CMP Pharma \/ Undisclosed"},{"orgOrder":0,"company":"Burke Therapeutics","sponsor":"Coeptis Pharmaceuticals","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"U.S.A","productType":"Miscellaneous","year":"2020","type":"Agreement","leadProduct":"Amlodipine Besylate","moa":"||Voltage-gated L-type calcium channel","graph1":"Neurology","graph2":"Approved FDF","graph3":"Burke Therapeutics","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Burke Therapeutics \/ Coeptis Pharmaceuticals","highestDevelopmentStatusID":"15","companyTruncated":"Burke Therapeutics \/ Coeptis Pharmaceuticals"}]

Find Clinical Drug Pipeline Developments & Deals for Istin, Norvasc, Amlodipine besylate

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                          Top Deals by Deal Size (USD bn)

                          01

                          FNCE
                          Not Confirmed
                          FNCE
                          Not Confirmed

                          Details : Widaplik is a combination tablet of telmisartan, an angiotensin II receptor blocker, amlodipine, a dihydropyridine calcium channel blocker, and indapamide, for treating hypertension.

                          Product Name : Widaplik

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          August 28, 2025

                          Lead Product(s) : Telmisartan,Amlodipine Besylate,Indapamide

                          Therapeutic Area : Cardiology/Vascular Diseases

                          Highest Development Status : Approved FDF

                          Sponsor : Piramal Pharma Solutions

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          FNCE
                          Not Confirmed
                          FNCE
                          Not Confirmed

                          Details : Caduet-Generic is a combinational medicine which consists of amlodipine besylate & atorvastatin calcium. It is indicated for the treatment of high blood pressure.

                          Product Name : Caduet-Generic

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          May 23, 2025

                          Lead Product(s) : Amlodipine Besylate,Atorvastatin

                          Therapeutic Area : Cardiology/Vascular Diseases

                          Highest Development Status : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          FNCE
                          Not Confirmed
                          FNCE
                          Not Confirmed

                          Details : Amlodipine Besylate is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Hypertension.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          December 29, 2022

                          Lead Product(s) : Amlodipine Besylate

                          Therapeutic Area : Cardiology/Vascular Diseases

                          Highest Development Status : Phase I

                          Sponsor : Health Start Pharmaceutical Technology

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          FNCE
                          Not Confirmed
                          FNCE
                          Not Confirmed

                          Details : Norliqva (Amlodipine) oral solution, 1 mg/mL, first and only FDA-approved oral liquid solution of the besylate salt of amlodipine, a long-acting calcium channel blocker, for treatment of hypertension in patients 6 years of age and older.

                          Product Name : Norliqva

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          June 01, 2022

                          Lead Product(s) : Amlodipine Besylate

                          Therapeutic Area : Cardiology/Vascular Diseases

                          Highest Development Status : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          FNCE
                          Not Confirmed
                          FNCE
                          Not Confirmed

                          Details : The objective is the contract development of a Single Pill with a combination of three leading active ingredients, including candesartan cilexetil, amlodipine besylate and atorvastatin calcium trihydrate for the treatment of high blood pressure (hyperten...

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Undisclosed

                          December 14, 2021

                          Lead Product(s) : Candesartan Cilexetil,Amlodipine Besylate,Atorvastatin

                          Therapeutic Area : Cardiology/Vascular Diseases

                          Highest Development Status : Phase III

                          Sponsor : Midas Pharma

                          Deal Size : Undisclosed

                          Deal Type : Partnership

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                          06

                          Shenzhen Ausa Pharmed Co.,Ltd

                          Country arrow
                          FNCE
                          Not Confirmed

                          Shenzhen Ausa Pharmed Co.,Ltd

                          Country arrow
                          FNCE
                          Not Confirmed

                          Lead Product(s) : Amlodipine Besylate

                          Therapeutic Area : Cardiology/Vascular Diseases

                          Study Phase : Phase IV

                          Sponsor : Peking University First Hospital | Second Affiliated Hospital, Nanchang University | The First People's Hospital of Lianyungang | The Affiliated Hospital Of Guizhou Medical University | Lianyungang Oriental Hospital | Tengzhou Central People's Hospital |

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Amlodipine Besylate is a Other Small Molecule drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Hypertension.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          July 23, 2021

                          Lead Product(s) : Amlodipine Besylate

                          Therapeutic Area : Cardiology/Vascular Diseases

                          Highest Development Status : Phase IV

                          Sponsor : Peking University First Hospital | Second Affiliated Hospital, Nanchang University | The First People's Hospital of Lianyungang | The Affiliated Hospital Of Guizhou Medical University | Lianyungang Oriental Hospital | Tengzhou Central People's Hospital |

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          Shenzhen Ausa Pharmed Co.,Ltd

                          Country arrow
                          FNCE
                          Not Confirmed

                          Shenzhen Ausa Pharmed Co.,Ltd

                          Country arrow
                          FNCE
                          Not Confirmed

                          Lead Product(s) : Amlodipine Besylate

                          Therapeutic Area : Cardiology/Vascular Diseases

                          Study Phase : Phase IV

                          Sponsor : Peking University First Hospital | Second Affiliated Hospital, Nanchang University | The First People's Hospital of Lianyungang | The Affiliated Hospital Of Guizhou Medical University | Lianyungang Oriental Hospital | Tengzhou Central People's Hospital |

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Amlodipine Besylate is a Other Small Molecule drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Hypertension.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          July 23, 2021

                          Lead Product(s) : Amlodipine Besylate

                          Therapeutic Area : Cardiology/Vascular Diseases

                          Highest Development Status : Phase IV

                          Sponsor : Peking University First Hospital | Second Affiliated Hospital, Nanchang University | The First People's Hospital of Lianyungang | The Affiliated Hospital Of Guizhou Medical University | Lianyungang Oriental Hospital | Tengzhou Central People's Hospital |

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          FNCE
                          Not Confirmed
                          FNCE
                          Not Confirmed

                          Details : Burke will market the fixed-dose combination drug, Consensi to lower blood pressure, and celecoxib for the management of the signs and symptoms of osteoarthritis.

                          Product Name : Consensi

                          Product Type : Miscellaneous

                          Upfront Cash : Undisclosed

                          March 11, 2020

                          Lead Product(s) : Amlodipine Besylate,Celecoxib

                          Therapeutic Area : Neurology

                          Highest Development Status : Approved FDF

                          Sponsor : Coeptis Pharmaceuticals

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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