Drugs in Dev.
Hematology
Phase I/ Phase II
United States Of America 
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Lead Product(s) : JBI-802
Therapeutic Area : Hematology
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
JBI-802 Phase I Data Suggests Potential in Immunotherapy-Resistant Tumors
Details : JBI-802 is a first-in-class CoREST inhibitor with dual action on LSD1 and HDAC6, undergoing phase 1/2 trials for essential thrombocythemia and related neoplasms.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
January 08, 2024
Lead Product(s) : JBI-802
Therapeutic Area : Hematology
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Dapivirine
Therapeutic Area : Hematology
Study Phase : Phase I/ Phase II
Sponsor : Gansu Provincial Maternal and Child Health Care Hospital | National Institutes of Health
Deal Size : Inapplicable
Deal Type : Inapplicable
PK, Safety Study of 90-Day Use of Vaginal Rings Containing Dapivirine and Levonorgestrel
Details : Dapivirine is a Other Small Molecule drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of Hemorrhage.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
September 13, 2021
Lead Product(s) : Dapivirine
Therapeutic Area : Hematology
Highest Development Status : Phase I/ Phase II
Sponsor : Gansu Provincial Maternal and Child Health Care Hospital | National Institutes of Health
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : SP-420
Therapeutic Area : Hematology
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : The PK data confirmed that the doses of SP-420 planned for the company's upcoming Phase 1-2 trial in patients with transfusional iron overload (TIO) should provide sufficient drug exposure for the desired therapeutic effect.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
October 06, 2020
Lead Product(s) : SP-420
Therapeutic Area : Hematology
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Marzeptacog Alpha,Coagulation Factor VIIa
Therapeutic Area : Hematology
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : MarzAA (Coagulation Factor VIIa) is a Protein drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of Factor VII Deficiency.
Product Name : MarzAA
Product Type : Protein
Upfront Cash : Inapplicable
September 16, 2020
Lead Product(s) : Marzeptacog Alpha,Coagulation Factor VIIa
Therapeutic Area : Hematology
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : INCB000928
Therapeutic Area : Hematology
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : INCB000928 is a Other Small Molecule drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of Anemia.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
July 02, 2020
Lead Product(s) : INCB000928
Therapeutic Area : Hematology
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : REGN7257
Therapeutic Area : Hematology
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : REGN7257 is a drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of Anemia, Aplastic.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Inapplicable
June 01, 2020
Lead Product(s) : REGN7257
Therapeutic Area : Hematology
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Exagamglogene Autotemcel
Therapeutic Area : Hematology
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
FDA offers CRISPR, Vertex drug program VIP status for its comeback play
Details : CTX001 has received Orphan Drug Designation from the U.S. FDA for transfusion-dependent beta thalassemia and from the EMA for sickle cell disease and transfusion-dependent beta thalassemia .
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
May 11, 2020
Lead Product(s) : Exagamglogene Autotemcel
Therapeutic Area : Hematology
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : CSL312
Therapeutic Area : Hematology
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : CSL312 is a Antibody drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of PICC-associated Thrombosis.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
February 24, 2020
Lead Product(s) : CSL312
Therapeutic Area : Hematology
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Mavorixafor
Therapeutic Area : Hematology
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Mavorixafor is a Other Small Molecule drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of Neutropenia.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
November 06, 2019
Lead Product(s) : Mavorixafor
Therapeutic Area : Hematology
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : SPK-8016
Therapeutic Area : Hematology
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : SPK-8016 is a Cell and Gene Therapy drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of Blood Coagulation Disorders.
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
November 08, 2018
Lead Product(s) : SPK-8016
Therapeutic Area : Hematology
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
