Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : HDT 321
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I
Sponsor : DFNet Research Inc. | Technical Resources International, Inc. (TRI) | BioAgilytix | University of Texas Medical Branch, Galveston | Clinical Trials of Texas | Quest Laboratories
Deal Size : Inapplicable
Deal Type : Inapplicable
Safety and Immunogenicity of a Self-Amplifying RNA Vaccine Against Crimean-Congo Hemorrhagic Fever
Details : Undisclosed
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Inapplicable
January 29, 2025
Lead Product(s) : HDT 321
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I
Sponsor : DFNet Research Inc. | Technical Resources International, Inc. (TRI) | BioAgilytix | University of Texas Medical Branch, Galveston | Clinical Trials of Texas | Quest Laboratories
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Undisclosed
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Discovery Platform
Recipient : MalarVx
Deal Size : Undisclosed
Deal Type : Licensing Agreement
MalarVx licenses HDT Bio's repRNA/LION™ Technology for Novel Malaria Vaccine
Details : Under the license agreement, MalarVx grants HDT access to the epRNA and LION platforms to support malaria vaccine formulation.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
January 16, 2025
Lead Product(s) : Undisclosed
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Discovery Platform
Recipient : MalarVx
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : HDT-521
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : BARDA
Deal Size : $0.7 million
Deal Type : Partnership
HDT Bio Receives $7.9M EZBAA Contract and Partners with BARDA for NextGen Enabler Program
Details : The partnership aims to support HDT in advancing its next-generation vaccine HDT-521. Which is being evaluated in the preclinical trial studies for the treatment of prostate cancer.
Product Name : Undisclosed
Product Type : Vaccine
Upfront Cash : Undisclosed
January 23, 2024
Lead Product(s) : HDT-521
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : BARDA
Deal Size : $0.7 million
Deal Type : Partnership
Lead Product(s) : saRNA Vaccine
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Preclinical
Recipient : UTMB
Deal Size : $87.4 million
Deal Type : Funding
Details : UTMB has partnered with HDT Bio Corp., to leverage the company’s self-amplifying RNA (saRNA) vaccine platform technology and proprietary LION™ delivery system to develop the vaccine candidates, identified as HDT-321 for CCHFV and HDT-331 for NiV.
Product Name : Undisclosed
Product Type : Vaccine
Upfront Cash : Undisclosed
November 30, 2022
Lead Product(s) : saRNA Vaccine
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Preclinical
Recipient : UTMB
Deal Size : $87.4 million
Deal Type : Funding
Lead Product(s) : HDT-301
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
HDT Bio’s COVID-19 Vaccine Wins Regulatory Approval in India
Details : The vaccine uses self-amplifying RNA (or “saRNA”), which replicates itself following administration and is thus effective at extremely low doses. In addition, it is stable at refrigerator temperatures—unlike current mRNA vaccines.
Product Name : Undisclosed
Product Type : Vaccine
Upfront Cash : Inapplicable
June 29, 2022
Lead Product(s) : HDT-301
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : HDT-301
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : HDT301, an HDT Bio’s technology uses self-replicating RNA and has the potential to deliver a COVID-19 vaccine targeting multiple variants, providing broad protection from disease and reduced transmission from breakthrough infections.
Product Name : Undisclosed
Product Type : Vaccine
Upfront Cash : Inapplicable
May 04, 2022
Lead Product(s) : HDT-301
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : HDT-301
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I
Sponsor : Quratis Co., Ltd
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Company RNA-based vaccine, HDT-301 (HGCO19) offers simpler manufacturing, greater stability, and vastly lower effective dosing than current mRNA COVID-19 vaccines.
Product Name : Undisclosed
Product Type : Vaccine
Upfront Cash : Inapplicable
December 13, 2021
Lead Product(s) : HDT-301
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I
Sponsor : Quratis Co., Ltd
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : HDT-301
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I
Sponsor : Rainier Clinical Research Center | C3 Research Associates
Deal Size : Inapplicable
Deal Type : Inapplicable
Safety and Immunogenicity of HDT-301 Targeting a SARS-CoV-2 Variant Spike Protein
Details : Undisclosed
Product Name : Undisclosed
Product Type : Vaccine
Upfront Cash : Inapplicable
November 24, 2021
Lead Product(s) : HDT-301
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I
Sponsor : Rainier Clinical Research Center | C3 Research Associates
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : HGCO19
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I/ Phase II
Recipient : Gennova Biopharmaceuticals
Deal Size : Inapplicable
Deal Type : Inapplicable
HDT Bio Corp and Gennova Complete Phase 1 Trial of COVID-19 RNA Vaccine in India
Details : Gennova Biopharmaceuticals, successfully completed a Phase 1 trial of its COVID-19 RNA vaccine candidate HGCO19 and Indian regulatory authorities have approved the start of pivotal Phase 2/3 trials.
Product Name : Undisclosed
Product Type : Vaccine
Upfront Cash : Inapplicable
August 31, 2021
Lead Product(s) : HGCO19
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I/ Phase II
Recipient : Gennova Biopharmaceuticals
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : HDT-301
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II/ Phase III
Sponsor : Quratis Co., Ltd
Deal Size : Undisclosed
Deal Type : Agreement
HDT Bio Announces Agreement With Korea’s Quratis to Co-Develop Innovative COVID-19 Vaccine in Asia
Details : This agreement will enable Quratis to manufacture HDT Bio's next-generation COVID-19 vaccine, HGCO19 and distribute it across much of East Asia.
Product Name : Undisclosed
Product Type : Vaccine
Upfront Cash : Undisclosed
August 16, 2021
Lead Product(s) : HDT-301
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II/ Phase III
Sponsor : Quratis Co., Ltd
Deal Size : Undisclosed
Deal Type : Agreement