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            Development Status

            Details:

            The net proceeds will be used to advance the Company’s preclinical and clinical pipeline, including EVX-01, a personalized cancer immunotherapy intended for the first-line treatment of metastatic and unresectable cancer patients.

            Lead Product(s): EVX-01,Pembrolizumab

            Therapeutic Area: Oncology Product Name: EVX-01

            Highest Development Status: Phase II Product Type: Vaccine

            Partner/Sponsor/Collaborator: H.C. Wainwright & Co.

            Deal Size: $15.0 million Upfront Cash: Undisclosed

            Deal Type: Public Offering February 06, 2024

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            The net proceeds will be used to advance the Company’s preclinical and clinical pipeline, including EVX-01, a personalized cancer immunotherapy intended for the first-line treatment of metastatic and unresectable cancer patients.

            Lead Product(s): EVX-01,Pembrolizumab

            Therapeutic Area: Oncology Product Name: EVX-01

            Highest Development Status: Phase II Product Type: Vaccine

            Partner/Sponsor/Collaborator: H.C. Wainwright & Co.

            Deal Size: $15.0 million Upfront Cash: Undisclosed

            Deal Type: Public Offering February 01, 2024

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            Evaxion Biotech is developing tailored cancer vaccines by targeting a novel category of AI-identified tumor antigens, named Endogenous Retroviruses (ERVs) to provide treatment solutions to cancer patients who are usually unresponsive to cancer immunotherapy.

            Lead Product(s): Undisclosed

            Therapeutic Area: Oncology Product Name: Undisclosed

            Highest Development Status: Preclinical Product Type: Vaccine

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable January 24, 2024

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            EVX-01 is a peptide-based personalized cancer vaccine which is being evaluated for first-line treatment of metastatic and unresectable cancer. It will engage each patient's immune system to fight off cancer by mounting a targeted response against tumors.

            Lead Product(s): EVX-01,Pembrolizumab

            Therapeutic Area: Oncology Product Name: EVX-01

            Highest Development Status: Phase II Product Type: Vaccine

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable October 31, 2023

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            The collaboration aims at developing a novel, prophylactic, mRNA vaccine, EVX-B2, based on Evaxion’s EDEN™ platform, a proprietary AI platform capable of rapidly identifying those antigens that will trigger a highly protective immune response, to discover gonorrhea targets.

            Lead Product(s): EVX-B2

            Therapeutic Area: Infections and Infectious Diseases Product Name: EVX-B2

            Highest Development Status: Preclinical Product Type: Vaccine

            Partner/Sponsor/Collaborator: Afrigen Biologics and Vaccines

            Deal Size: Undisclosed Upfront Cash: Undisclosed

            Deal Type: Collaboration September 20, 2023

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            EVX-B3, an AI-designed vaccine using both its EDEN™ and RAVEN™ AI platforms to identify protective antigens capable of eliciting both a humoral (antibody) and cellular response to the pathogen.

            Lead Product(s): EVX-B3

            Therapeutic Area: Infections and Infectious Diseases Product Name: EVX-B3

            Highest Development Status: Preclinical Product Type: Vaccine

            Partner/Sponsor/Collaborator: Undisclosed

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable September 18, 2023

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            The net proceeds will enable Evaxion to advance its ongoing clinical phase 2 trial, EVX-01, in patients with metastatic melanoma and its next-generation cancer vaccine, EVX-03, towards a Phase 1 clinical trial in patients with lung cancer and other solid tumors.

            Lead Product(s): EVX-01,Pembrolizumab

            Therapeutic Area: Oncology Product Name: EVX-01

            Highest Development Status: Phase II Product Type: Vaccine

            Partner/Sponsor/Collaborator: Negma Group

            Deal Size: $20.0 million Upfront Cash: Undisclosed

            Deal Type: Financing August 01, 2023

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            EVX-B1, a vaccine against Staphylococcus aureus (S. aureus) containing AI-identified antigens, is highly protective against S. aureus disease in preclinical animal models.

            Lead Product(s): EVX-B1

            Therapeutic Area: Infections and Infectious Diseases Product Name: EVX-B1

            Highest Development Status: Preclinical Product Type: Vaccine

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable July 31, 2023

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            EVX-02 is a DNA-based neoantigen cancer immunotherapy in combination with the checkpoint inhibitor nivolumab is intended for the adjuvant treatment of patients with advanced resectable melanoma.

            Lead Product(s): EVX-02,Nivolumab

            Therapeutic Area: Oncology Product Name: EVX-02

            Highest Development Status: Phase I/ Phase II Product Type: Vaccine

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable April 18, 2023

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            The preclinical data demonstrate that tumor neoantigens identified by Evaxion’s AI platform, PIONEER, drive a strong immune response and lead to complete inhibition of tumor growth in a preclinical model.

            Lead Product(s): mRNA-based Vaccine

            Therapeutic Area: Oncology Product Name: Undisclosed

            Highest Development Status: Preclinical Product Type: Vaccine

            Partner/Sponsor/Collaborator: Pantherna Therapeutics

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable February 08, 2023

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