Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
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Product Type
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Lead Product
Target
Details : The company has received final approval from the Danish Medicines Agency and Ethical Committee to initiate a clinical trial with the drug candidate SCO-101 in combination with first line chemotherapy in patients with inoperable or metastatic pancreatic c...
Product Name : SCO-101
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
September 28, 2020
Lead Product(s) : Endovion,Fluorouracil,Calcium Folinate
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : First part of the trial aimed at establishing the safety, tolerability and Maximum Tolerated Dose of SCO-101 in combination with FOLFIRI. One patient has obtained stable disease, according to RECIST version 1.1 at 8 weeks after starting the treatment.
Product Name : SCO-101
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
August 20, 2020
Lead Product(s) : Endovion,Fluorouracil,Calcium Folinate
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Endovion,Fluorouracil,Calcium Folinate
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : The main result of oral SCO-101 potentiates the effects of FOLFIRI. Based on safety data from this first cohort of patients, Data Safety Monitoring Board has recommended to include 3 additional patients at 150 mg SCO-101and FOLFIRI.
Product Name : SCO-101
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
July 31, 2020
Lead Product(s) : Endovion,Fluorouracil,Calcium Folinate
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
SCO-101 works in synergy with the chemotherapy drug docetaxel in drug resistant cancer cells
Details : Based on modelling of preclinical data with docetaxel resistant cancer cells, Scandion Oncology has published that SCO-101 significantly increases the potency of docetaxel.
Product Name : SCO-101
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
March 25, 2020
Lead Product(s) : Endovion
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Clinical development plans for SCO-101
Details : Phase II trial of SCO-101 treats a critical condition with no satisfactory treatment choice, thus Scandion has agreed to continue the research of colorectal cancer with patients resistant to FOLFIRI.
Product Name : SCO-101
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
March 23, 2020
Lead Product(s) : Endovion
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Scandion Oncology receives DKK 5 million
Details : The grant of DKK 5 million from Innovation Fund Denmark is earmarked for the clinical phase II development of SCO-101 in metastatic pancreatic cancer.
Product Name : SCO-101
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
February 19, 2020