
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : ENA-001
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase I
Sponsor : National Institute on Drug Abuse
Deal Size : Inapplicable
Deal Type : Inapplicable
ENA-001 for Opioid Induced Respiratory Depression
Details : ENA-001 is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Respiratory Insufficiency.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
May 13, 2025
Lead Product(s) : ENA-001
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase I
Sponsor : National Institute on Drug Abuse
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : ENA-001
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
ENA-001 for Post Operative Respiratory Depression (PORD)
Details : ENA-001 is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Respiratory Insufficiency.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
November 18, 2023
Lead Product(s) : ENA-001
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : ENA-001
Therapeutic Area : Sleep
Study Phase : Preclinical
Sponsor : National Institutes of Health
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Enalare's lead compound, ENA-001, is a one-of-a-kind new chemical entity (NCE) designed as an agnostic respiratory stimulant. The compound has a novel mechanism of action that affects ventilation via the peripheral chemoreceptor pathways in the carotid b...
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
October 03, 2022
Lead Product(s) : ENA-001
Therapeutic Area : Sleep
Highest Development Status : Preclinical
Sponsor : National Institutes of Health
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : ENA-001
Therapeutic Area : Sleep
Study Phase : Preclinical
Recipient : Eagle Pharmaceuticals
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : ENA-001, is a one-of-a-kind new chemical entity (NCE) designed as an agnostic respiratory stimulant. The compound has a novel mechanism of action that affects ventilation via the peripheral chemoreceptor pathways in the carotid body.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
October 03, 2022
Lead Product(s) : ENA-001
Therapeutic Area : Sleep
Highest Development Status : Preclinical
Recipient : Eagle Pharmaceuticals
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : ENA-001
Therapeutic Area : Psychiatry/Psychology
Study Phase : Preclinical
Sponsor : BARDA
Deal Size : $56.3 million
Deal Type : Funding
Details : In partnership with BARDA, ENA-001 is being developed in an intramuscular (“IM”) formulation for potential use in patients experiencing community drug overdose and as a potential medical countermeasure for mass casualty events.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
September 27, 2022
Lead Product(s) : ENA-001
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Preclinical
Sponsor : BARDA
Deal Size : $56.3 million
Deal Type : Funding

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Lead Product(s) : ENA-001
Therapeutic Area : Sleep
Study Phase : Preclinical
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Rare Pediatric Disease Designation received for ENA-001, a unique agnostic respiratory stimulant has the potential to significantly improve the standard of care for neonates experiencing life-threatening and debilitating respiratory conditions.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
December 14, 2021
Lead Product(s) : ENA-001
Therapeutic Area : Sleep
Highest Development Status : Preclinical
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
