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[{"orgOrder":0,"company":"Emtora Biosciences","sponsor":"Not Applicable","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not Applicable","newsHeadline":"Emtora Presents Phase Ib Data in Low Grade Prostate Cancer","therapeuticArea":"Oncology","highestDevelopmentStatus":"Phase I","country":"U.S.A","productType":"Small molecule","productStatus":"Approved","date":"February 2020","url1":"","url2":"","graph1":"Oncology","graph2":"Phase I"},{"orgOrder":0,"company":"Emtora Biosciences","sponsor":"Cancer Prevention & Research Institute of Texas","pharmaFlowCategory":"D","amount":"$19.9 million","upfrontCash":"Undisclosed","newsHeadline":"Emtora Biosciences Receives $16.9M Grant from the Cancer Prevention & Research Institute of Texas","therapeuticArea":"Oncology","highestDevelopmentStatus":"Phase II","country":"U.S.A","productType":"Small molecule","productStatus":"Approved","date":"August 2022","url1":"","url2":"","graph1":"Oncology","graph2":"Phase II"},{"orgOrder":0,"company":"Emtora Biosciences","sponsor":"Biodexa Pharmaceuticals","pharmaFlowCategory":"D","amount":"$41.5 million","upfrontCash":"Undisclosed","newsHeadline":"Biodexa Enters Into Exclusive License to eRapa\u2122, a Phase 3 Ready Asset for the Treatment of Familial Adenomatous Polyposis (FAP)","therapeuticArea":"Genetic Disease","highestDevelopmentStatus":"Phase II","country":"U.S.A","productType":"Small molecule","productStatus":"Approved","date":"April 2024","url1":"","url2":"","graph1":"Genetic Disease","graph2":"Phase II"}]

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            Details:

            Under the agreement, Biodexa gain rights to develop, manufacture, commercialize and otherwise advance the clinical potential of eRapa, a proprietary oral tablet formulation of rapamycin and an mTOR inhibitor, for the treatment of Familial Adenomatous Polyposis.

            Lead Product(s): Sirolimus

            Therapeutic Area: Genetic Disease Product Name: eRapa

            Highest Development Status: Phase II Product Type: Small molecule

            Partner/Sponsor/Collaborator: Biodexa Pharmaceuticals

            Deal Size: $41.5 million Upfront Cash: Undisclosed

            Deal Type: Licensing Agreement April 26, 2024

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            Details:

            Emtora plans to use the CPRIT award to complete a multicenter, randomized, placebo-controlled Phase 3 trial of eRapa (rapamycin) in patients with FAP. Patients with FAP are predisposed to the development of hundreds or even thousands of polyps in their gastrointestinal tract.

            Lead Product(s): Sirolimus

            Therapeutic Area: Oncology Product Name: eRapa

            Highest Development Status: Phase II Product Type: Small molecule

            Partner/Sponsor/Collaborator: Cancer Prevention & Research Institute of Texas

            Deal Size: $19.9 million Upfront Cash: Undisclosed

            Deal Type: Funding August 19, 2022

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            In patients with low-grade PCa, treatment with low dose eRapa was found to be safe and well-tolerated.

            Lead Product(s): Sirolimus

            Therapeutic Area: Oncology Product Name: Undisclosed

            Highest Development Status: Phase I Product Type: Small molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable February 04, 2020

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