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(durvalumab) plus Chemotherapy Doubled Overall Survival Rate at Three Years for Patients with Advanced Biliary Tract Cancer in TOPAZ-1 Phase III Trial","therapeuticArea":"Oncology","highestDevelopmentStatus":"Phase III","country":"UNITED KINGDOM","productType":"Large molecule","productStatus":"Approved","date":"April 2024","url1":"","url2":"","graph1":"Oncology","graph2":"Phase III"}]
Find Clinical Drug Pipeline Developments & Deals for Durvalumab
Imfinzi (durvalumab) is a human monoclonal antibody that binds to the PD-L1 protein and blocks the interaction of PD-L1 with the PD-1 and CD80 proteins. It is being evaluated for the treatment of patients with locally advanced or metastatic biliary tract cancer.
Imfinzi (durvalumab) is a PD-L1 Inhibitor antibody drug candidate, which is currently being evaluated in combination with tremelimumab for the treatment of limited-stage small cell lung cancer.
Imfinzi (durvalumab), a PD-L1 inhibitor plus platinum-based chemotherapy followed by Imfinzi plus Lynparza (olaparib), a PARP inhibitor, demonstrated an improvement in patients with mismatch repair proficient advanced endometrial cancer compared to chemotherapy alone.
Ampligen (rintatolimod) is a TLR-3 agonist which is under phase 1/2 clinical development in combination with Imfinzi (durvalumab) for the treatment of pancreatic cancer.
Ampligen (rintatolimod) is a TLR-3 agonist which is being evaluated under phase 1/2 clinical trials in combination with anti-PD-L1 immune checkpoint inhibitor Imfinzi (durvalumab) for the treatment of late-stage pancreatic cancer.
Transarterial Chemoembolization (TACE) in combination with Imfinzi (Durvalumab) and Bevacizumab is being evaluated in phase 3 clinical trials for the treatment of Hepatocellular Carcinoma.
Ampligen (rintatolimod) is a TLR-3 agonist which is under phase 1/2 clinical development in combination with Imfinzi (durvalumab) for the treatment of pancreatic cancer.
Imfinzi (durvalumab) a PD-L1 inhibitor in combination with Dato-DXd (datopotamab deruxtecan) a TOP1 inhibitor is being evaluated in phase 3 clinical trials for the treatment of patients with early-stage triple negative and HR low, HER2 low or negative breast cancers.
Lead Product(s):
Datopotamab Deruxtecan,Durvalumab
Imfinzi (durvalumab) is a human monoclonal antibody that binds to the PD-L1 protein and blocks the interaction of PD-L1 with the PD-1 and CD80 proteins. It is being evaluated in phase 3 clinical trials for the treatment of unresectable, Stage III non-small cell lung cancer.
Imfinzi (durvalumab) is a human monoclonal antibody that binds to the PD-L1 protein and blocks the interaction of PD-L1 with the PD-1 and CD80 proteins. It is approved for the treatment of patients with locally advanced or metastatic biliary tract cancer in China.
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