Company profile for Exelixis

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About

Exelixis, Inc., from the Greek word for “evolution,” is a biopharmaceutical company committed to developing and commercializing small molecule therapies with the potential to improve the treatment of cancer. Over the past decade, we have established a broad development platform, laying the foundation for our continued efforts to bring new therapies for cancer to patients in need. The history of our lead compounds, caboz...
Exelixis, Inc., from the Greek word for “evolution,” is a biopharmaceutical company committed to developing and commercializing small molecule therapies with the potential to improve the treatment of cancer. Over the past decade, we have established a broad development platform, laying the foundation for our continued efforts to bring new therapies for cancer to patients in need. The history of our lead compounds, cabozantinib and cobimetinib, tell the story of our evolution as a company. Each of these compounds were discovered in our own laboratories and advanced by us into clinical development.

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CONTACT DETAILS

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Country
Country
U.S.A
Address
Address
210 East Grand Avenue
Telephone
Telephone
650 837 8194, (650) 837-7000
Client Website
Website
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Linkedin
Linkedin
youtube
YouTube
Twitter
Twitter

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Events

Webinars & Exhibitions

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NEWS #PharmaBuzz

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https://www.businesswire.com/news/home/20260224844659/en/Exelixis-to-Webcast-Fireside-Chats-as-Part-of-Upcoming-Investor-Conferences-in-March

BUSINESSWIRE
24 Feb 2026

https://www.businesswire.com/news/home/20260210781065/en/Exelixis-Announces-Fourth-Quarter-and-Fiscal-Year-2025-Financial-Results-and-Provides-Corporate-Update

BUSINESSWIRE
10 Feb 2026

https://www.businesswire.com/news/home/20260130221586/en/Exelixis-Announces-U.S.-FDA-Accepted-the-New-Drug-Application-for-Zanzalintinib-in-Combination-with-an-Immune-Checkpoint-Inhibitor-for-Patients-with-Metastatic-Colorectal-Cancer

BUSINESSWIRE
02 Feb 2026

https://www.businesswire.com/news/home/20260127808059/en/Exelixis-to-Release-Fourth-Quarter-and-Fiscal-Year-2025-Financial-Results-on-Tuesday-February-10-2026

BUSINESSWIRE
27 Jan 2026

https://www.fiercebiotech.com//www.fiercepharma.com/pharma/single-product-exelixis-aims-be-top-5-solid-tumor-drugmaker-us

FIERCE BIOTECH
16 Jan 2026

https://www.businesswire.com/news/home/20260111609689/en/Exelixis-Announces-Preliminary-Fiscal-Year-2025-Financial-Results-Provides-2026-Financial-Guidance-and-Outlines-Key-Priorities-and-Milestones-for-2026

BUSINESSWIRE
11 Jan 2026

Drugs in Development

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Details:

XL092 (Zanzalintinib) is a small molecule drug, which is currently being evaluated in Phase II clinical studies for the treatment of meningioma.


Lead Product(s): Encoberminogene Rezmadenovec

Therapeutic Area: Oncology Brand Name: XL092

Study Phase: Phase IIProduct Type: Miscellaneous

Sponsor: Undisclosed

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable February 24, 2026

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Exelixis

U.S.A
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BioProcess International US West
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Exelixis

U.S.A
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BioProcess International US West
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Details : XL092 (Zanzalintinib) is a small molecule drug, which is currently being evaluated in Phase II clinical studies for the treatment of meningioma.

Product Name : XL092

Product Type : Miscellaneous

Upfront Cash : Inapplicable

February 24, 2026

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Details:

The collaboration aims to advance the clinical development of Zanzalintinib for colo-rectal cancer by targeting AXL, MerTK, VEGFR1, and c-Met.


Lead Product(s): Encoberminogene Rezmadenovec

Therapeutic Area: Oncology Brand Name: XL092

Study Phase: Phase IIIProduct Type: Miscellaneous

Sponsor: Natera

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Collaboration January 07, 2026

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Exelixis

U.S.A
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BioProcess International US West
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Exelixis

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BioProcess International US West
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Details : The collaboration aims to advance the clinical development of Zanzalintinib for colo-rectal cancer by targeting AXL, MerTK, VEGFR1, and c-Met.

Product Name : XL092

Product Type : Miscellaneous

Upfront Cash : Undisclosed

January 07, 2026

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Details:

XL-092 (Zanzalintinib) is a small molecule drug candidate, which is currently being evaluated in Phase II clinical studies for the treatment of Soft-Tissue Sarcoma.


Lead Product(s): Encoberminogene Rezmadenovec,Pembrolizumab

Therapeutic Area: Oncology Brand Name: XL-092

Study Phase: Phase IIProduct Type: Miscellaneous

Recipient: The University of Texas MD Anderson Cancer Center

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable December 16, 2025

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Exelixis

U.S.A
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BioProcess International US West
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Exelixis

U.S.A
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BioProcess International US West
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Details : XL-092 (Zanzalintinib) is a small molecule drug candidate, which is currently being evaluated in Phase II clinical studies for the treatment of Soft-Tissue Sarcoma.

Product Name : XL-092

Product Type : Miscellaneous

Upfront Cash : Inapplicable

December 16, 2025

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Details:

Belzutifan is a small molecule drug candidate, which is currently being evaluated in Phase III clinical studies for the treatment of Carcinoma, Renal Cell.


Lead Product(s): Belzutifan,Encoberminogene Rezmadenovec

Therapeutic Area: Oncology Brand Name: Undisclosed

Study Phase: Phase IIIProduct Type: Miscellaneous

Recipient: Merck & Co

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable November 12, 2025

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Exelixis

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BioProcess International US West
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Exelixis

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BioProcess International US West
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Details : Belzutifan is a small molecule drug candidate, which is currently being evaluated in Phase III clinical studies for the treatment of Carcinoma, Renal Cell.

Product Name : Undisclosed

Product Type : Miscellaneous

Upfront Cash : Inapplicable

November 12, 2025

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Details:

Durvalumab is an antibody candidate, which is currently being evaluated in Phase II clinical studies for the treatment of Carcinoma, Hepatocellular.


Lead Product(s): Durvalumab,Encoberminogene Rezmadenovec

Therapeutic Area: Oncology Brand Name: Undisclosed

Study Phase: Phase IIProduct Type: Antibody, Unconjugated

Sponsor: Exelixis

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable November 07, 2025

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Exelixis

U.S.A
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BioProcess International US West
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Exelixis

U.S.A
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BioProcess International US West
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Details : Durvalumab is an antibody candidate, which is currently being evaluated in Phase II clinical studies for the treatment of Carcinoma, Hepatocellular.

Product Name : Undisclosed

Product Type : Antibody, Unconjugated

Upfront Cash : Inapplicable

November 07, 2025

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Details:

Zanzalintinib in Men With Aggressive Variant Prostate Cancer is a small molecule drug candidate, which is currently being evaluated in Phase II studies for the treatment of Prostatic Neoplasms.


Lead Product(s): Encoberminogene Rezmadenovec

Therapeutic Area: Oncology Brand Name: Undisclosed

Study Phase: Phase IIProduct Type: Miscellaneous

Sponsor: Deepak Kilari | Medical College of Wisconsin

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable October 20, 2025

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Exelixis

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BioProcess International US West
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Exelixis

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BioProcess International US West
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Lead Product(s) : Encoberminogene Rezmadenovec

Therapeutic Area : Oncology

Highest Development Status : Phase II

Partner/Sponsor/Collaborator : Deepak Kilari | Medical College of Wisconsin

Deal Size : Inapplicable

Deal Type : Inapplicable

Details : Zanzalintinib in Men With Aggressive Variant Prostate Cancer is a small molecule drug candidate, which is currently being evaluated in Phase II studies for the treatment of Prostatic Neoplasms.

Product Name : Undisclosed

Product Type : Miscellaneous

Upfront Cash : Inapplicable

October 20, 2025

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Details:

Zanzalintinib is a Small Molecule drug candidate drug candidate, which is currently being evaluated in Phase II clinical studies for the treatment of Bone Neoplasms.


Lead Product(s): Encoberminogene Rezmadenovec

Therapeutic Area: Oncology Brand Name: Undisclosed

Study Phase: Phase IIProduct Type: Miscellaneous

Recipient: MD Anderson Cancer Center

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable September 26, 2025

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Exelixis

U.S.A
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BioProcess International US West
Not Confirmed

Exelixis

U.S.A
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BioProcess International US West
Not Confirmed

Details : Zanzalintinib is a Small Molecule drug candidate drug candidate, which is currently being evaluated in Phase II clinical studies for the treatment of Bone Neoplasms.

Product Name : Undisclosed

Product Type : Miscellaneous

Upfront Cash : Inapplicable

September 26, 2025

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Details:

Cabozantinib is a Small Molecule drug candidate drug candidate, which is currently being evaluated in Phase I clinical studies for the treatment of Carcinoma, Renal Cell.


Lead Product(s): Cabozantinib,Nivolumab

Therapeutic Area: Oncology Brand Name: Undisclosed

Study Phase: Phase IProduct Type: Miscellaneous

Recipient: MD Anderson Cancer Center

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable September 23, 2025

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Exelixis

U.S.A
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BioProcess International US West
Not Confirmed

Exelixis

U.S.A
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BioProcess International US West
Not Confirmed

Details : Cabozantinib is a Small Molecule drug candidate drug candidate, which is currently being evaluated in Phase I clinical studies for the treatment of Carcinoma, Renal Cell.

Product Name : Undisclosed

Product Type : Miscellaneous

Upfront Cash : Inapplicable

September 23, 2025

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Details:

Encoberminogene Rezmadenovec is a Cell & Gene Therapy drug candidate, which is currently being evaluated in Phase II clinical studies for the treatment of Carcinoma, Transitional Cell.


Lead Product(s): Encoberminogene Rezmadenovec

Therapeutic Area: Oncology Brand Name: Undisclosed

Study Phase: Phase IIProduct Type: Cell & Gene Therapy

Sponsor: Advent Health

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable September 22, 2025

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Exelixis

U.S.A
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BioProcess International US West
Not Confirmed

Exelixis

U.S.A
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BioProcess International US West
Not Confirmed

Details : Encoberminogene Rezmadenovec is a Cell & Gene Therapy drug candidate, which is currently being evaluated in Phase II clinical studies for the treatment of Carcinoma, Transitional Cell.

Product Name : Undisclosed

Product Type : Cell & Gene Therapy

Upfront Cash : Inapplicable

September 22, 2025

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Details:

Exelixis will utilize Adagene’s SAFEbody technology platform to generate a masked monoclonal antibody from the company’s pipeline for the development of an ADC.


Lead Product(s): Undisclosed

Therapeutic Area: Oncology Brand Name: Undisclosed

Study Phase: DiscoveryProduct Type: Antibody-drug Conjugate

Recipient: Adagene Suzhou Limited

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Expanded Collaboration September 16, 2025

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Exelixis

U.S.A
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BioProcess International US West
Not Confirmed

Exelixis

U.S.A
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BioProcess International US West
Not Confirmed

Details : Exelixis will utilize Adagene’s SAFEbody technology platform to generate a masked monoclonal antibody from the company’s pipeline for the development of an ADC.

Product Name : Undisclosed

Product Type : Antibody-drug Conjugate

Upfront Cash : Undisclosed

September 16, 2025

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FDF Dossiers

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Brand Name : COMETRIQ

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Brand Name : COMETRIQ

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Exelixis

Dosage Form : CAPSULE;ORAL

Brand Name : COMETRIQ

Dosage Strength : EQ 20MG BASE

Packaging :

Approval Date : 2012-11-29

Application Number : 203756

Regulatory Info : RX

Registration Country : USA

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Brand Name : COMETRIQ

BioProcess International US West
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Brand Name : COMETRIQ

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Exelixis

Dosage Form : CAPSULE;ORAL

Brand Name : COMETRIQ

Dosage Strength : EQ 80MG BASE

Packaging :

Approval Date : 2012-11-29

Application Number : 203756

Regulatory Info : RX

Registration Country : USA

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Brand Name : CABOMETYX

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Brand Name : CABOMETYX

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Exelixis

Dosage Form : TABLET;ORAL

Brand Name : CABOMETYX

Dosage Strength : EQ 20MG BASE

Packaging :

Approval Date : 2016-04-25

Application Number : 208692

Regulatory Info : RX

Registration Country : USA

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Brand Name : CABOMETYX

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Brand Name : CABOMETYX

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Exelixis

Dosage Form : TABLET;ORAL

Brand Name : CABOMETYX

Dosage Strength : EQ 40MG BASE

Packaging :

Approval Date : 2016-04-25

Application Number : 208692

Regulatory Info : RX

Registration Country : USA

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Brand Name : CABOMETYX

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Brand Name : CABOMETYX

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Exelixis

Dosage Form : TABLET;ORAL

Brand Name : CABOMETYX

Dosage Strength : EQ 60MG BASE

Packaging :

Approval Date : 2016-04-25

Application Number : 208692

Regulatory Info : RX

Registration Country : USA

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