

Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : Dotinurad,Allopurinol
Therapeutic Area : Rheumatology
Study Phase : Phase I/ Phase II
Sponsor : Novo Holdings
Deal Size : $205.0 million
Deal Type : Series A Financing
Novo-Backed Crystalys Debuts With $205M to Tackle Gout
Details : The financing round will support the advancement of Phase 3 evaluating, FYU-981 (dotinurad), a next-generation, once daily oral, URAT1 inhibitor for the treatment of gout.
Product Name : FYU-981
Product Type : Miscellaneous
Upfront Cash : Undisclosed
September 30, 2025
Lead Product(s) : Dotinurad,Allopurinol
Therapeutic Area : Rheumatology
Highest Development Status : Phase I/ Phase II
Sponsor : Novo Holdings
Deal Size : $205.0 million
Deal Type : Series A Financing

Lead Product(s) : Dotinurad
Therapeutic Area : Rheumatology
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
A Study of Dotinurad Versus Allopurinol in Participants with Gout
Details : Dotinurad is a Other Small Molecule drug candidate, which is currently being evaluated in Phase III clinical studies for the treatment of Gout.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
July 28, 2025
Lead Product(s) : Dotinurad
Therapeutic Area : Rheumatology
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

Lead Product(s) : Dotinurad
Therapeutic Area : Rheumatology
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
A Study of Dotinurad Versus Allopurinol in Tophaceous Gout
Details : Dotinurad is a Other Small Molecule drug candidate, which is currently being evaluated in Phase III clinical studies for the treatment of Gout.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
July 28, 2025
Lead Product(s) : Dotinurad
Therapeutic Area : Rheumatology
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Dotinurad
Therapeutic Area : Rheumatology
Study Phase : Approved FDF
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Thailand Approves New Therapeutic Medicine for Gout and Hyperuricemia
Details : Dotinurad, a novel urate transporter (URAT1) inhibitor for gout with potential to address other conditions associated with hyperuricemia such as chronic kidney disease.
Product Name : Urece
Product Type : Miscellaneous
Upfront Cash : Inapplicable
October 08, 2024
Lead Product(s) : Dotinurad
Therapeutic Area : Rheumatology
Highest Development Status : Approved FDF
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Dotinurad
Therapeutic Area : Rheumatology
Study Phase : Phase I
Sponsor : Fortress Biotech
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Dotinurad, a novel urate transporter (URAT1) inhibitor for gout with potential to address other conditions associated with hyperuricemia such as chronic kidney disease.
Product Name : Urece
Product Type : Miscellaneous
Upfront Cash : Inapplicable
June 29, 2023
Lead Product(s) : Dotinurad
Therapeutic Area : Rheumatology
Highest Development Status : Phase I
Sponsor : Fortress Biotech
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Dotinurad
Therapeutic Area : Rheumatology
Study Phase : Approved FDF
Sponsor : Urica Therapeutics
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Details : Urece (dotinurad) is a potential best-in-class urate transporter inhibitor that is currently in Phase 1 clinical trial and being developed for the treatment of gout. It can lower blood uric acid levels by selectively inhibiting URAT1 and uric acid reabso...
Product Name : Urece
Product Type : Miscellaneous
Upfront Cash : Undisclosed
December 14, 2022
Lead Product(s) : Dotinurad
Therapeutic Area : Rheumatology
Highest Development Status : Approved FDF
Sponsor : Urica Therapeutics
Deal Size : Undisclosed
Deal Type : Licensing Agreement

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Lead Product(s) : Dotinurad
Therapeutic Area : Rheumatology
Study Phase : Approved FDF
Sponsor : Fuji Yakuhin
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Dotinurad (URECE® tablet) was approved in Japan in 2020 as a once-daily oral therapy for gout and hyperuricemia. Dotinurad was efficacious and well-tolerated in more than 500 Japanese patients treated for up to 58 weeks in Phase 3 clinical trials.
Product Name : Urece
Product Type : Miscellaneous
Upfront Cash : Inapplicable
May 31, 2022
Lead Product(s) : Dotinurad
Therapeutic Area : Rheumatology
Highest Development Status : Approved FDF
Sponsor : Fuji Yakuhin
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Dotinurad
Therapeutic Area : Undisclosed
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
A Single and Multiple Dose Study of Dotinurad in Chinese Healthy Participants
Details : Dotinurad is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of undefined medical condition.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
March 14, 2022
Lead Product(s) : Dotinurad
Therapeutic Area : Undisclosed
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Dotinurad
Therapeutic Area : Rheumatology
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
A Study to Evaluate Efficacy of Dotinurad and Febuxostat for the Treatment of Participants With Gout
Details : Dotinurad is a Other Small Molecule drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Gout.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
August 16, 2021
Lead Product(s) : Dotinurad
Therapeutic Area : Rheumatology
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Dotinurad
Therapeutic Area : Rheumatology
Study Phase : Approved FDF
Sponsor : Fortress Biotech
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Details : Dotinurad is a potential best-in-class urate transporter (URAT1) inhibitor that was approved for the treatment of gout and hyperuricemia in Japan in 2020.
Product Name : Urece
Product Type : Miscellaneous
Upfront Cash : Undisclosed
May 10, 2021
Lead Product(s) : Dotinurad
Therapeutic Area : Rheumatology
Highest Development Status : Approved FDF
Sponsor : Fortress Biotech
Deal Size : Undisclosed
Deal Type : Licensing Agreement
