Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Alkyon Therapeutics
Deal Size : Undisclosed
Deal Type : Collaboration
Debiopharm and Alkyon Announce Research Collaboration to Advance Radioligand Therapies
Details : The collaboration aims to evaluate the feasibility of developing targeted radioligand therapies using Debiopharm’s proprietary AbYlink™ conjugation technology for Alkyon’s modular antibody platform.
Product Name : Undisclosed
Product Type : Radiolabelled Compounds
Upfront Cash : Undisclosed
June 12, 2025
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Alkyon Therapeutics
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Oncodesign
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Debiopharm and Oncodesign Launch Strategic Collaboration for Radiopharmaceuticals
Details : Under the licensing agreement, Oncodesign will holds the rights of AbYlink technology aiming for drug discovery and preclinical services.
Product Name : Undisclosed
Product Type : Radiolabelled Compounds
Upfront Cash : Undisclosed
April 24, 2025
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Oncodesign
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : Debio 0123,Sacituzumab Govitecan
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : MEDSIR
Deal Size : Inapplicable
Deal Type : Inapplicable
MEDSIR & Debiopharm Begin WIN-B Trial in Breast Cancer
Details : Debio 0123 is an oral, potent, highly selective, and brain-penetrant WEE1 inhibitor is being evaluated with trodelvy for HR-positive/HER2-negative triple negative breast neoplasms.
Product Name : Debio 0123
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
February 25, 2025
Lead Product(s) : Debio 0123,Sacituzumab Govitecan
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : MEDSIR
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : 177-Lu DPI-4452,68-Ga DPI-4452
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Isotope Technologies Munich
Deal Size : $330.8 million
Deal Type : Licensing Agreement
ITM Licenses CA IX-Targeted Radiopharmaceutical Programs from Debiopharm
Details : ITM gains the exclusive global license for the clinical and commercial development of the peptide-based, theranostic pair ITM-91/ITM-94D, targeting the Carbonic Anhydrase IX (CA IX) surface protein.
Product Name : ITM-91
Product Type : Peptide
Upfront Cash : Undisclosed
December 09, 2024
Lead Product(s) : 177-Lu DPI-4452,68-Ga DPI-4452
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Isotope Technologies Munich
Deal Size : $330.8 million
Deal Type : Licensing Agreement
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Study Phase : Discovery Platform
Sponsor : Whitelab Genomics
Deal Size : Undisclosed
Deal Type : Partnership
Debiopharm and WhiteLab Partner On Oncology Drug Target Design
Details : Debiopharm strategic partnership to leverage WhiteLab’s proprietary AI platform for identifying agents that provide targeting properties to non-viral vectors in oncology.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
September 16, 2024
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Discovery Platform
Sponsor : Whitelab Genomics
Deal Size : Undisclosed
Deal Type : Partnership
Lead Product(s) : SRB19
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : SunRock Biopharma
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Debiopharm Extends Partnership with SunRock for HER3 Targeted Antibody
Details : SunRock will develop SRB19, a HER3-EGFR bispecific antibody-drug conjugate for head and neck cancer, using Debiopharm's Multilink technology.
Product Name : SRB19
Product Type : Other Large Molecule
Upfront Cash : Undisclosed
August 01, 2024
Lead Product(s) : SRB19
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : SunRock Biopharma
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : Debio 0123
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Debiopharm Expands WEE1 Inhibitor Research in Gynecological and Biomarker-Driven Tumors
Details : Debio 0123, an oral, potent, highly selective, and brain-penetrant WEE1 inhibitor is being evaluated in Phase I clinical trial studies for patients with advanced solid tumors.
Product Name : Debio 0123
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
July 03, 2024
Lead Product(s) : Debio 0123
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Debio 0123,Carboplatin,Etoposide
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Debio 0123 is a brain-penetrant, highly selective WEE1 kinase inhibitor combines with standard-of-care therapy to short-circuit DNA damage repair (DDR) in adults with recurrent or progressive small cell lung cancer (SCLC).
Product Name : Debio 0123
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
May 30, 2023
Lead Product(s) : Debio 0123,Carboplatin,Etoposide
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Debio 0123,Temozolomide
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Debio 0123 is a brain-penetrant and highly selective WEE1 inhibitor, it is being investigated in combination with temozolomide (TMZ) in patients with recurrent or progressive glioblastoma and in combination with TMZ/RT (SOC) in newly diagnosed patients.
Product Name : Debio 0123
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
May 17, 2023
Lead Product(s) : Debio 0123,Temozolomide
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : 68-Ga DPI-4452,177-Lu DPI-4452
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Debio 0328 ([68Ga]Ga-DPI-4452) and Debio 0228 ([177Lu]Lu-DPI-4452) are the only peptide-based theranostic pair targeting CAIX in clinical development, with pan-tumor potential, and developed first for patients with advanced cancers such as renal, pancrea...
Product Name : Debio 0328
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
March 22, 2023
Lead Product(s) : 68-Ga DPI-4452,177-Lu DPI-4452
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable