[{"orgOrder":0,"company":"Hamad Medical Corporation","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Rare Diseases and Disorders","country":"QATAR","productType":"Amino Acid","year":"2024","type":"Inapplicable","leadProduct":"L-Cysteine","moa":"Glutamate--cysteine ligase regulatory subunit; Glutamate--cysteine ligase catalytic subunit; Aspartate aminotransferase, cytoplasmic; Aspartate aminotransferase, mitochondrial; Cystathionine gamma-lyase; Cystathionine beta-synthase; Cysteine--tRNA ligase, cytoplasmic; Methylated-DNA--protein-cysteine methyltransferase; Glutathione synthetase; Probable cysteine--tRNA ligase, mitochondrial; Cysteine sulfinic acid decarboxylase; Cysteine desulfurase; Cysteine dioxygenase type 1","graph1":"Rare Diseases and Disorders","graph2":"Undisclosed","graph3":"Hamad Medical Corporation","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Rare Diseases","amount2New":0,"dosageForm":"Powder","sponsorNew":"Hamad Medical Corporation \/ Undisclosed","highestDevelopmentStatusID":"1","companyTruncated":"Hamad Medical Corporation \/ Undisclosed"},{"orgOrder":0,"company":"Biohit","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Psychiatry\/Psychology","country":"FINLAND","productType":"Amino Acid","year":"2016","type":"Inapplicable","leadProduct":"L-Cysteine","moa":"Glutamate--cysteine ligase regulatory subunit; Glutamate--cysteine ligase catalytic subunit; Aspartate aminotransferase, cytoplasmic; Aspartate aminotransferase, mitochondrial; Cystathionine gamma-lyase; Cystathionine beta-synthase; Cysteine--tRNA ligase, cytoplasmic; Methylated-DNA--protein-cysteine methyltransferase; Glutathione synthetase; Probable cysteine--tRNA ligase, mitochondrial; Cysteine sulfinic acid decarboxylase; Cysteine desulfurase; Cysteine dioxygenase type 1","graph1":"Psychiatry\/Psychology","graph2":"Undisclosed","graph3":"Biohit","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Psychiatry","amount2New":0,"dosageForm":"Troche\/Lozenge","sponsorNew":"Biohit \/ Undisclosed","highestDevelopmentStatusID":"1","companyTruncated":"Biohit \/ Undisclosed"},{"orgOrder":0,"company":"Centre for Addiction and Mental Health","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Undisclosed","country":"CANADA","productType":"Amino Acid","year":"2015","type":"Inapplicable","leadProduct":"L-Cysteine","moa":"Glutamate--cysteine ligase regulatory subunit; Glutamate--cysteine ligase catalytic subunit; Aspartate aminotransferase, cytoplasmic; Aspartate aminotransferase, mitochondrial; Cystathionine gamma-lyase; Cystathionine beta-synthase; Cysteine--tRNA ligase, cytoplasmic; Methylated-DNA--protein-cysteine methyltransferase; Glutathione synthetase; Probable cysteine--tRNA ligase, mitochondrial; Cysteine sulfinic acid decarboxylase; Cysteine desulfurase; Cysteine dioxygenase type 1","graph1":"Undisclosed","graph2":"Phase I","graph3":"Centre for Addiction and Mental Health","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Centre for Addiction and Mental Health \/ Undisclosed","highestDevelopmentStatusID":"6","companyTruncated":"Centre for Addiction and Mental Health \/ Undisclosed"},{"orgOrder":0,"company":"Per Hellstr\u00f6m","sponsor":"Biohit | University of Helsinki | \u00c5bo Akademi University | CTC Clinical Trial Consultants","pharmaFlowCategory":"DU","therapeuticArea":"Gastroenterology","country":"","productType":"Amino Acid","year":"2015","type":"Inapplicable","leadProduct":"L-Cysteine","moa":"Glutamate--cysteine ligase regulatory subunit; Glutamate--cysteine ligase catalytic subunit; Aspartate aminotransferase, cytoplasmic; Aspartate aminotransferase, mitochondrial; Cystathionine gamma-lyase; Cystathionine beta-synthase; Cysteine--tRNA ligase, cytoplasmic; Methylated-DNA--protein-cysteine methyltransferase; Glutathione synthetase; Probable cysteine--tRNA ligase, mitochondrial; Cysteine sulfinic acid decarboxylase; Cysteine desulfurase; Cysteine dioxygenase type 1","graph1":"Gastroenterology","graph2":"Phase II","graph3":"Per Hellstr\u00f6m","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Gastroenterology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Per Hellstr\u00f6m \/ Biohit | University of Helsinki | \u00c5bo Akademi University | CTC Clinical Trial Consultants","highestDevelopmentStatusID":"8","companyTruncated":"Per Hellstr\u00f6m \/ Biohit | University of Helsinki | \u00c5bo Akademi University | CTC Clinical Trial Consultants"},{"orgOrder":0,"company":"Liliana Berenice Ram\u00edrez Dom\u00ednguez","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Obstetrics\/Gynecology (Women\u2019s Health)","country":"","productType":"Peptide, Unconjugated","year":"2023","type":"Inapplicable","leadProduct":"L-Cysteine","moa":"Glutathione","graph1":"Obstetrics\/Gynecology (Women\u2019s Health)","graph2":"Undisclosed","graph3":"Liliana Berenice Ram\u00edrez Dom\u00ednguez","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Gynecology\/Obstetrics","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Liliana Berenice Ram\u00edrez Dom\u00ednguez \/ Undisclosed","highestDevelopmentStatusID":"1","companyTruncated":"Liliana Berenice Ram\u00edrez Dom\u00ednguez \/ Undisclosed"}]

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                          Top Deals by Deal Size (USD bn)

                          01

                          Hamad Medical Corporation

                          Country arrow
                          OTS 2025
                          Not Confirmed

                          Hamad Medical Corporation

                          Country arrow
                          OTS 2025
                          Not Confirmed

                          Details : Cysteine is a Other Small Molecule drug candidate, which is currently being evaluated in clinical studies for the treatment of Homocystinuria.

                          Product Name : Undisclosed

                          Product Type : Amino Acid

                          Upfront Cash : Inapplicable

                          October 02, 2024

                          Lead Product(s) : L-Cysteine

                          Therapeutic Area : Rare Diseases and Disorders

                          Highest Development Status : Undisclosed

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          Liliana Berenice Ramírez Domínguez

                          Country arrow
                          OTS 2025
                          Not Confirmed

                          Liliana Berenice Ramírez Domínguez

                          Country arrow
                          OTS 2025
                          Not Confirmed

                          Details : Cystein is a Peptide drug candidate, which is currently being evaluated in clinical studies for the treatment of Infertility, Female.

                          Product Name : Undisclosed

                          Product Type : Peptide, Unconjugated

                          Upfront Cash : Inapplicable

                          June 26, 2023

                          Lead Product(s) : L-Cysteine

                          Therapeutic Area : Obstetrics/Gynecology (Women’s Health)

                          Highest Development Status : Undisclosed

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          Biohit

                          Country arrow
                          OTS 2025
                          Not Confirmed

                          Biohit

                          Country arrow
                          OTS 2025
                          Not Confirmed

                          Details : L-Cysteine is a Other Small Molecule drug candidate, which is currently being evaluated in clinical studies for the treatment of Smoking Cessation.

                          Product Name : Undisclosed

                          Product Type : Amino Acid

                          Upfront Cash : Inapplicable

                          May 02, 2016

                          Lead Product(s) : L-Cysteine

                          Therapeutic Area : Psychiatry/Psychology

                          Highest Development Status : Undisclosed

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          Per Hellström

                          Country arrow
                          OTS 2025
                          Not Confirmed

                          Per Hellström

                          Country arrow
                          OTS 2025
                          Not Confirmed

                          Lead Product(s) : L-Cysteine

                          Therapeutic Area : Gastroenterology

                          Study Phase : Phase II

                          Sponsor : Biohit | University of Helsinki | Åbo Akademi University | CTC Clinical Trial Consultants

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : L-Cysteine is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Gastritis, Atrophic.

                          Product Name : Undisclosed

                          Product Type : Amino Acid

                          Upfront Cash : Inapplicable

                          August 14, 2015

                          Lead Product(s) : L-Cysteine

                          Therapeutic Area : Gastroenterology

                          Highest Development Status : Phase II

                          Sponsor : Biohit | University of Helsinki | Åbo Akademi University | CTC Clinical Trial Consultants

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          Centre for Addiction and Mental Health

                          Country arrow
                          OTS 2025
                          Not Confirmed

                          Centre for Addiction and Mental Health

                          Country arrow
                          OTS 2025
                          Not Confirmed

                          Details : L-Cysteine is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of undefined medical condition.

                          Product Name : Undisclosed

                          Product Type : Amino Acid

                          Upfront Cash : Inapplicable

                          June 04, 2015

                          Lead Product(s) : L-Cysteine

                          Therapeutic Area : Undisclosed

                          Highest Development Status : Phase I

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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