[{"orgOrder":0,"company":"Center for Breakthrough Medicines","sponsor":"Achilles Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"UNITED KINGDOM","productType":"Cell & Gene Therapy","year":"2022","type":"Partnership","leadProduct":"ATL001","moa":"T-cell receptor","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Center for Breakthrough Medicines","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Center for Breakthrough Medicines \/ Center for Breakthrough Medicines","highestDevelopmentStatusID":"7","companyTruncated":"Center for Breakthrough Medicines \/ Center for Breakthrough Medicines"},{"orgOrder":0,"company":"Center for Breakthrough Medicines","sponsor":"jCyte","pharmaFlowCategory":"D","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Cell & Gene Therapy","year":"2022","type":"Partnership","leadProduct":"Allogeneic Human Retinal Progenitor Cell","moa":"Undisclosed","graph1":"Genetic Disease","graph2":"Phase II","graph3":"Center for Breakthrough Medicines","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Injection","sponsorNew":"Center for Breakthrough Medicines \/ Center for Breakthrough Medicines","highestDevelopmentStatusID":"8","companyTruncated":"Center for Breakthrough Medicines \/ Center for Breakthrough Medicines"},{"orgOrder":0,"company":"Center for Breakthrough Medicines","sponsor":"Virion Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Vaccine","year":"2023","type":"Collaboration","leadProduct":"Undisclosed","moa":"||Undisclosed","graph1":"Infections and Infectious Diseases","graph2":"IND Enabling","graph3":"Center for Breakthrough Medicines","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Injection","sponsorNew":"Center for Breakthrough Medicines \/ Virion Therapeutics","highestDevelopmentStatusID":"5","companyTruncated":"Center for Breakthrough Medicines \/ Virion Therapeutics"}]

Find Clinical Drug Pipeline Developments & Deals by Center for Breakthrough Medicines

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                          Top Deals by Deal Size (USD bn)

                          01

                          AAPS
                          Not Confirmed
                          AAPS
                          Not Confirmed

                          Details : Under the terms of the collaboration, CBM will manufacture and partner with Virion on their checkpoint modifier clinical development programs, including the First-in-Human VRON-0200 immunotherapy for patients with chronic Hepatitis B Virus (HBV) infectio...

                          Product Name : Undisclosed

                          Product Type : Vaccine

                          Upfront Cash : Undisclosed

                          February 22, 2023

                          Lead Product(s) : VRON-0200,Undisclosed

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : IND Enabling

                          Sponsor : Virion Therapeutics

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          02

                          AAPS
                          Not Confirmed
                          AAPS
                          Not Confirmed

                          Lead Product(s) : Human Retinal Progenitor Cell,Allogeneic Human Retinal Progenitor Cell

                          Therapeutic Area : Genetic Disease

                          Study Phase : Phase II

                          Recipient : jCyte

                          Deal Size : Undisclosed

                          Deal Type : Partnership

                          Details : Under the terms of the agreement, CBM will provide Phase 3 clinical trial supplies and commercial drug product following Biologics License Application (BLA) approval of jCyte’s proprietary jCell platform technology working on human retinal progenitor c...

                          Product Name : jCell

                          Product Type : Cell & Gene Therapy

                          Upfront Cash : Undisclosed

                          September 20, 2022

                          Lead Product(s) : Human Retinal Progenitor Cell,Allogeneic Human Retinal Progenitor Cell

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase II

                          Recipient : jCyte

                          Deal Size : Undisclosed

                          Deal Type : Partnership

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                          03

                          AAPS
                          Not Confirmed
                          AAPS
                          Not Confirmed

                          Details : The second GMP manufacturing site will initially support Achilles’ proprietary VELOS™ manufacturing process with an annual capacity of 200 cNeT (Clonal NeoantigenT-cells) doses at peak production. The Company’s first US GMP manufacturing facility t...

                          Product Name : Undisclosed

                          Product Type : Cell & Gene Therapy

                          Upfront Cash : Undisclosed

                          April 12, 2022

                          Lead Product(s) : ATL001

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Recipient : Achilles Therapeutics

                          Deal Size : Undisclosed

                          Deal Type : Partnership

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